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Optical Coherence Tomography Angiography of the Eye

David Huang, Bruno Lumbroso, and Yali Jia

Optical coherence tomography angiography (OCTA) has undergone tremendous growth since its first commercial introduction in 2014. Because it provides injection-free, capillary-resolution, 3-dimensional angiography of the retina and choroid, OCTA is likely to overtake fluorescein as the most important angiographic imaging technique in the eye. Nearly all manufacturers of ophthalmic OCT now offer OCTA products. A PubMed search now yields over 5700 articles on OCTA and related terms.Clinical investigators have already found a use for OCTA in almost every category of retinal and optic nerve diseases. This book is meant to bring together all this information so clinicians can have one authoritative text to turn to as we begin to use this new imaging modality that was never taught when we were in formal training. Table of contents IntroductionDedicationAbout the EditorsContributors1. Optical coherence tomography systems for angiography2. Optical coherence tomographic angiography algorithms3. Vascular anatomy of the normal retina and choroid4. OCTA of the normal anterior eye circulations5. Artifacts6. Quantification7. Artificial intelligence in optical coherence tomographic angiography8. a new standard9. AngioVue SSADA OCTA on the Optovue SOLIX Spectral-Domain OCT10. Optical microangiography with AngioPlex® and PLEX® Elite systems11. Optical coherence tomography angiography imaging on the Topcon Triton and Maestro2 systems12. NIDEK Mirante OCT angiography13. OCTA on the Heidelberg spectralis spectral-domain OCT14. OCTA on the Optopol REVO NX spectral-domain OCT15. OCTA on the Canon OCT-HS100 and Xephilio OCT-A1 Spectral-Domain OCT16. Exudative neovascular age-related macular degeneration—Type 1, 2 and 3 neovascularization17. Retinal angiomatous proliferation—type 3 choroidal neovascularization18. Short- and long-term follow-up of macular neovascularization response to antiangiogenic treatment19. Nonexudative neovascular age-related macular degeneration20. Non-neovascular age-related macular degeneration21. Polypoidal choroidal vasculopathy22. Macular telangiectasia23. Central serous chorioretinopathy25. Nonproliferative diabetic retinopathy26. Subclinical neovascular diabetic retinopathy27. Proliferative diabetic retinopathy28. Retinal venous occlusion29. Retinal arterial occlusion30. Plexus-specific occlusions in retinal vascular diseases31. Paracentral acute middle maculopathy32. Inherited retinal degenerations33. Pathologic myopia34. Multimodal imaging and the role of optical coherence tomography angiography in retinal vasculitis35. White spot syndromes36. Choroidal tumors37. Radiation retinopathy38. Open-angle glaucoma39. Primary angle-closure glaucoma40. Optic neuritis and multiple sclerosis41. Alzheimer’s disease42. Corneal neovascularization43. Ocular surface and iris tumors

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