Stereochemistry of Organic Compounds

KEY * Subject treated from fundamental and developed to the latest developments.

* A large cross-section of organic reactions/mechanisms given with stereochemical implications.

* Relationship between conformation and reactivity specially highlighted.

* Instrumentation techniques relating to stereochemical investigation discussed in simple language. ABOUT THE During recent years, stereochemistry has undergone a phenomenal growth both in theory and practice, with a concomitant increase of interest among the organic chemists, biological chemists, medicinal chemists, and pharmacologists. The present text provides an up-to-date, coherent, and comprehensive account of the subject starting from the fundamentals and leading up to the latest developments as far as practicable. Emphasis has been placed on a symmetry-based approach to molecular chirality, stereochemical terminologies (modern stereochemistry is replete with them), topicity and prostereoisomerism, conformational analysis, dynamic stereochemistry, chiroptical properties, and assignment of absolute configuration to chiral molecules. Dynamic stereochemistry has been discussed with reference to conformation-reactivity correlation, stereoselective synthesis, and pericyclic reactions. A large cross-section of organic reactions with stereochemical implication has been incorporated. Attempts have been made to familiarise the readers with modern instrumental techniques, nuclear magnetic resonance in particular, used for stereochemical investigation. Each chapter is provided with a summary which highlights the main points of the text. * Molecular Geometry and Chemical Bonding

* Molecular Symmetry and Chirality

* Definitions and Classifications

* Stereoisomerism and Centre of Chirality

* Axial Chirality, Planar Chirality and Helicity

* Topicity and Prostereoisomerism

* Racemisation and Methods of Resolution

* Determination of Configuration

* Conformations of Acyclic Molecules

* Conformations of Cyclic Monocyclic Compounds

* Conformations of Cyclic Fused Ring and Bridged Ring Compounds

* Dynamic Stereochemistry Conformation and Reactivity

* Dynamic Stereochemistry Reactions

* Dynamic Stereochemistry Reactions

* Molecular Dissymmetry and Chiroptical Properties

* Molecular Chemical and Stereochemical Aspects * Graduate and postgraduate students of Chemistry courses

* University and college libraries

* Biochemists, Medical and Pharmacology students and other related professionals

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