April 11, 2024
4 minute read
Structural Biology is the study of the structure of biomolecules, such as proteins and nucleic acids, and the relationships between their structure and function. Structural biologists use techniques such as X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy to determine the atomic structures of biomolecules.
What does a Structural Biologist do?
Structural biologists play a vital role in understanding the molecular basis of life. Their work has contributed to the development of new drugs, vaccines, and treatments for diseases such as cancer and HIV/AIDS.
Here are some of the tasks that structural biologists may perform:
- Design and conduct experiments to determine the atomic structures of biomolecules
- Develop new methods for determining the structures of biomolecules
- Interpret the results of structural studies to understand the function of biomolecules
- Collaborate with other scientists to develop new drugs and treatments for diseases
- Publish their findings in scientific journals and present their work at conferences
How do you become a Structural Biologist?
To become a structural biologist, you will typically need a PhD in biochemistry, biophysics, or a related field. You will also need to have strong skills in mathematics, physics, and computer science.
Many structural biologists work in academic research institutions, while others work in government or industry. If you are interested in a career in structural biology, you should start by earning a bachelor's degree in a science field such as biology, chemistry, or physics.
What are the challenges of being a Structural Biologist?
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Find a path to becoming a Structural Biologist. Learn more at:
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Reading list
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Provides a comprehensive overview of proteins, including the structure, function, and bioinformatics. It can be used as a textbook for advanced undergraduates and graduates.
Presents a rigorous and comprehensive treatment of protein structure, with a focus on the principles that govern protein folding and stability. It is suitable for advanced undergraduate and graduate students.
This classic textbook provides a comprehensive overview of protein structure, covering topics such as protein folding, dynamics, and interactions. It is written in a clear and accessible style, making it suitable for both undergraduate and graduate students.
Provides a comprehensive overview of protein structure and molecular properties. It is written for advanced undergraduates, graduates, and researchers in biochemistry, biophysics, and chemistry.
This textbook is suitable for advanced undergraduates, graduates, and researchers in biochemistry. It provides comprehensive coverage of the structure and function of proteins.
Provides a comprehensive overview of molecular modeling, including the use of protein structures in drug design and discovery. It is written for advanced undergraduates, graduates, and researchers in biochemistry, biophysics, and chemistry.
Covers a broad range of topics in physical biochemistry, including the structure and function of proteins. It is written for advanced undergraduates, graduates, and researchers in biochemistry, biophysics, and chemistry.
Provides a comprehensive overview of drug design, including the role of protein structures in drug discovery. It is written for advanced undergraduates, graduates, and researchers in biochemistry, pharmacology, and chemistry.
Provides a comprehensive overview of protein NMR spectroscopy, with a focus on the theoretical and practical aspects of the technique. It is suitable for advanced undergraduate and graduate students.
Provides a comprehensive overview of electron microscopy, with a focus on the theoretical and practical aspects of the technique. It is suitable for advanced undergraduate and graduate students.
This textbook concise and well-written introduction to the structure, function, and evolution of proteins. It is written with a clear and engaging style, making it an excellent choice for students in biochemistry, biophysics, and related disciplines.
Provides a comprehensive overview of bioinformatics, with a focus on the practical aspects of the field. It is suitable for advanced undergraduate and graduate students.
For more information about how these books relate to this course, visit:
OpenCourser.com/career/souzun/structural