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Immunology

The Immune System and its Failures

Malgorzata (Maggie) Trela and Sophie Rutschmann

Our online Immunology Specialisation has been developed to provide central concepts in human immunology as well as advanced topics from cutting-edge research relating to clinical disease of the immune system over five designated specialisations.

The initial two courses discuss the role of the innate and adaptive immune responses serving to protect the body from harmful pathogens, which if dysregulated can also lead to immune-mediated diseases such as immunodeficiencies, autoimmunity, allergy and chronic infection, evaluated in the remaining three courses.

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What's inside

Five courses

Immunology: Innate Immune System

Our immune system's innate arm provides our first, fast and inherited defence against infections. This course focuses on the mechanisms and cellular components involved in this swift response that occurs within minutes of exposure to a threat.

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Immunology: Adaptive Immune System

In this course, you will learn about the adaptive immune system, which provides specialized immunity against pathogens. We will focus on the lymphocyte subsets and mechanisms involved in this delayed finely tuned response occurring days to weeks after the initial exposure to microbial antigens.

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Immunology: Autoimmunity, Allergy, and Transplants

In this course, you will explore the mechanisms and immune responses involved in autoimmune diseases and hyper-responsive phenomena, such as asthma. You will examine the potential causes and factors behind an overactive immune system and the disorders that might ensue if the response is not adequately controlled.

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Immunology: Immune System and Infectious Diseases

The constant struggle between pathogens and the human immune system has been posing a significant threat to our health for thousands of years. Infectious diseases remain the leading cause of death worldwide. These are typically caused by bacteria, viruses, fungi, parasites, and prions. Under normal circumstances, the immune response orchestrates a robust protection against these pathogens using both molecular and cellular mechanisms.

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Immunology: Immune Failures and Cancer Immunology

Our immune system protects us from threats, including harmful substances and pathogenic agents, as well as cellular changes that could lead to diseases. When our natural defenses do not function properly, immune disorders can result.

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Learning objectives

You will learn central concepts in human immunology and advanced topics from cutting-edge research relating to clinical disease of the immune system.

You will link this knowledge to everyday relevant immunological manifestations (autoimmunity, defense against infectious diseases, tumor immunology).

You will learn central concepts in human immunology and advanced topics from cutting-edge research relating to clinical disease of the immune system.
You will link this knowledge to everyday relevant immunological manifestations (autoimmunity, defense against infectious diseases, tumor immunology).

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Time

26 hours

Level

Intermediate

Via

Coursera

Institution

Imperial College London

Instructors

Malgorzata (Maggie) Trela

Sophie Rutschmann

Level

Intermediate

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