Whole Genome Sequencing

Most FutureLearn courses run multiple times. Every run of a course has a set start date but you can join it and work through it after it starts. Find out more The course has been designed for healthcare professionals and science/medical students who have limited or no understanding of the who genome sequencing process and its many varied uses. Non-specialists who want to learn more about sequencing and genomic medicine are also very welcome. You don’t need an in-depth knowledge of genetics, as this course will provide a recap on the basics. The course is designed in such a way that you can move as quickly or slowly as you wish; so, while some scientific knowledge will be beneficial, the course is open to anyone who wants to learn about whole genome sequencing and its impact in healthcare. If you’re a healthcare professional, you may find it useful to upgrade this course to support your continuing professional development (CPD). By upgrading, you’ll be able to take this course at your own pace and revisit the material at any time in future. Once you complete the course, you’ll receive a Certificate of Achievement as evidence of your CPD. This includes details of what you learnt and the number of learning hours required. You can use the hashtag #FLwgs to talk about this course on social media.

Topics Covered

The composition, structure and function of a genome.
The process and the importance of DNA replication.
Genomic variation and its connections with health and disease.
The evolution of genome sequencing.
The advent and the possibilities of next generation sequencing.
The preparation and processing of DNA samples in whole genome sequencing.
The interpretation of genomic information for clinicians and patients.
The limitations and challenges faced by current sequencing technologies.
Additional, incidental and secondary findings from whole genome sequencing.
The ownership, storing and sharing of genomic data.
The impact of whole genome sequencing on healthcare in the future.

Reviews summary

Foundational whole genome sequencing overview

According to learners, this course offers a solid foundation in Whole Genome Sequencing, from its basics to its clinical applications and future implications. Many praise its clear explanations, accessible content, and flexible pace, making complex topics understandable. Students particularly value the modules on data interpretation, ethical considerations, and the impact on healthcare. However, some advanced learners found it too introductory, while a few true beginners felt it assumed prior knowledge despite promising a recap of basics. Overall, it's a highly relevant course, especially for healthcare professionals and students, providing a comprehensive, though sometimes less interactive, learning experience.

Highly valued for its focus on healthcare applications and ethics.

"I found this course incredibly insightful for understanding the clinical applications of WGS."

"The topics on future impact and data sharing were particularly thought-provoking."

"I particularly valued the emphasis on ethical considerations and the future of genomic medicine."

Provides a strong and accessible understanding of WGS.

"This course provided a very solid foundation in whole genome sequencing."

"Excellent overview! I'm a student with a basic genetics background, and this course really filled in the gaps regarding WGS."

"Fantastic! This course provided an excellent overview of WGS from its fundamentals to its implications for healthcare."

Could benefit from more practical exercises and active discussions.

"I sometimes wished for more interactive elements or practical exercises beyond the quizzes to deepen understanding."

"Some of the video quality was a little inconsistent, and the forum discussions weren't always very active, which limited the peer-to-peer learning aspect."

"I felt that some modules, especially those on interpretation for clinicians, could have benefited from more real-world examples or interactive problem-solving."

Some true beginners found it assumed too much prior knowledge.

"I struggled a bit with this course. While it claims to recap basics, I felt it assumed more prior knowledge than advertised..."

"The pace felt uneven, and some explanations were too brief for a complete novice."

"I had to look up a lot of terms externally. Disappointed that it wasn't as beginner-friendly as I hoped."

Great for novices but lacks depth for advanced learners.

"Decent course, but a bit too introductory for my taste. I have a Ph.D. in molecular biology..."

"It's great if you're a beginner, but for someone with prior knowledge, it felt a bit slow and superficial in parts."

"It's a foundational course, so don't expect deep dives into advanced bioinformatics, but it sets a strong stage."

Career center

Learners who complete Whole Genome Sequencing: Decoding the Language of Life and Health will develop knowledge and skills that may be useful to these careers: