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Abel Bult-Ito

The study of neuroscience aims to understand the human brain, cognition, the nervous system, and much more. There are many branches of neuroscience, including medical neuroscience, computational neuroscience, and behavioral neuroscience. Studying the human brain can be difficult, so scientists often first use mice in research because of the similarities in neuroanatomy, neurophysiology, and neurobiology. By studying the brains of mice, we gain insight into how the human brain works. This behavioral neuroscience course on edx covers the fundamentals of research involving mice, mice behavior and how it can be used to understand human behavior, and more. Enroll now to:

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The study of neuroscience aims to understand the human brain, cognition, the nervous system, and much more. There are many branches of neuroscience, including medical neuroscience, computational neuroscience, and behavioral neuroscience. Studying the human brain can be difficult, so scientists often first use mice in research because of the similarities in neuroanatomy, neurophysiology, and neurobiology. By studying the brains of mice, we gain insight into how the human brain works. This behavioral neuroscience course on edx covers the fundamentals of research involving mice, mice behavior and how it can be used to understand human behavior, and more. Enroll now to:

  • Understand how to handle laboratory mice responsibly according to federal law by completing animals care and use training.

  • Understand how research on animals must be scientifically justified, humane and ethical, use appropriate research methods, and provide new knowledge.

  • Collect behavioral data from mouse videos from compulsive-like, non-compulsive-like, and randomly bred mouse strains; a mouse model of obsessive-compulsive disorder (OCD).

  • Obtain competency in using behavioral tests to measure repetitive behaviors in laboratory mice analogous to compulsions in humans.

  • Establish a foundation in using behavioral tests in laboratory mice to be able to confidently learn how to use new tests.

  • Develop an ability to analyze behavioral neuroscience data using mice and understand repetitive (compulsive-like) behaviors in animal models.

  • Develop an ability to interpret and discuss results in the context of human behavior, and especially psychiatric disorders, and the mouse model of OCD.

  • Obtain a competency in describing key characteristics of OCD in humans and human behavior as described in the diagnostic and statistical manual of mental disorders (DSM), including obsessive and intrusive thoughts, repetitive behaviors, and hoarding disorder.

  • Develop a capability to formulate original research hypotheses as used in the fields of behavioral sciences, neuropsychology, and behavioral neuroscience.

  • Obtain a competency in describing and discussing how basic research contributes to the animal model of OCD and how it may have the potential to improve human mental health conditions, quality of life and the biological basis of human behavior.

Learners who join this course should be free of objections to using mice in research.

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What's inside

Learning objectives

  • Learn responsible conduct of research.
  • Collect, analyze, and interpret behavioral data from mouse videos.
  • Establish a foundation in using behavioral tests in laboratory mice.
  • Understand obsessive-compulsive disorder in humans and compulsions in animals.
  • Understand the role of animal models in studying human psychiatry.

Syllabus

Module 1: Introduction, Animal Care and Use Training
Module 2: Ethics of Animal Research
Module 3: OCD in humans and compulsive like behavior in mice (nesting)
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Module 4: Compulsive-like behavior: Data collection and analysis of marble burying behavior
Module 5: Interpretation of results

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Covers the basics of research on mice, their behavior, and how it can be used to understand human behavior
Develops the foundational knowledge and skills to conduct research on animal models of psychiatric disorders
Recommended for individuals who are interested in conducting or understanding research on animal models of psychiatric disorders
Provides training in animal care and use, experimental design, and data analysis
Taught by instructors who are recognized for their work in behavioral neuroscience
Requires participants to be free of objections to using mice in research

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Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Behavioral Neuroscience: Foundations of Compulsive Behaviors with these activities:
Volunteer at an animal shelter or rescue organization
Gain practical experience in animal care and behavior by volunteering at an organization dedicated to animal well-being.
Browse courses on Animal Welfare
Show steps
  • Identify local animal shelters or rescue organizations.
  • Inquire about volunteer opportunities and requirements.
  • Attend training sessions and familiarize yourself with the organization's policies.
  • Engage in hands-on activities such as feeding, grooming, and socializing with animals.
Explore online tutorials on animal handling techniques
Enhance your understanding of ethical and responsible animal care practices by exploring online tutorials and resources.
Show steps
  • Visit the website of the National Institutes of Health (NIH) Office of Laboratory Animal Welfare.
  • Enroll in free online courses on animal handling offered by organizations like edX or Coursera.
  • Attend a workshop or seminar on best practices in animal research.
  • Review the guidelines set by the Institutional Animal Care and Use Committee (IACUC).
Review of physiology associated with key neurotransmitters
Review the functions and physiological effects of neurotransmitters to refresh your understanding of the core concepts covered in this course.
Browse courses on Neuroscience
Show steps
  • Revisit textbooks or lecture notes from previous neuroscience or biology courses.
  • Explore online resources such as Khan Academy or Coursera for refresher materials.
  • Attend a seminar or workshop on neurotransmitter physiology.
Three other activities
Expand to see all activities and additional details
Show all six activities
Review of 'Essentials of Behavioral Neuroscience' by Jon C. Horvitz
Supplement your understanding of behavioral neuroscience by reviewing a foundational textbook that provides a comprehensive overview of the field.
Show steps
  • Obtain a copy of the book.
  • Read through the chapters and take notes on key concepts.
  • Complete the end-of-chapter exercises.
Analyze simulated mouse behavior data
Develop your analytical skills by practicing the analysis of mouse behavior data, which is crucial for understanding the results presented in the course.
Browse courses on Behavioral Neuroscience
Show steps
  • Access online databases or software that provide simulated mouse behavior data.
  • Apply the behavioral analysis techniques covered in the course to interpret the data.
  • Compare your results with those provided by the instructor or other peers.
  • Attend a lab session or workshop on mouse behavior analysis.
Create a presentation on the ethical implications of animal research
Deepen your understanding of the ethical responsibilities involved in animal research by creating a presentation that explores the topic.
Show steps
  • Research ethical guidelines and regulations related to animal research.
  • Consider the perspectives of different stakeholders, including scientists, animal welfare advocates, and the general public.
  • Develop arguments and present your views on the ethical implications of animal research.
  • Share your presentation with classmates or a broader audience for feedback.

Career center

Learners who complete Behavioral Neuroscience: Foundations of Compulsive Behaviors will develop knowledge and skills that may be useful to these careers:
Neuroscientist
Neuroscientists study the nervous system. They may work in a variety of settings, including universities, research laboratories, and hospitals. This course may be useful for future Neuroscientists. It provides a strong foundation in behavioral neuroscience, which is essential for understanding the nervous system.
Behavioral Scientist
Behavioral Scientists study the behavior of humans and animals. They may work in a variety of settings, including research laboratories, universities, and government agencies. This course may be useful for those who want to become Behavioral Scientists. It helps build a foundation in behavioral neuroscience, including the study of obsessive-compulsive disorder in humans and compulsive-like behavior in mice. This knowledge is essential for someone who wants to work as a Behavioral Scientist.
Cognitive Scientist
Cognitive Scientists study the mind and how it works. They may work in a variety of settings, including universities, research laboratories, and private companies. This course may be useful for someone interested in becoming a Cognitive Scientist. It provides a strong foundation in behavioral neuroscience, which is essential for understanding the mind and how it works.
Psychologist
Psychologists study the mind and how it works. They may work in a variety of settings, including universities, research laboratories, and private practices. This course may be useful for future Psychologists. It provides a strong foundation in behavioral neuroscience, which is essential for understanding the mind and how it works.
Mental Health Counselor
Mental Health Counselors help people with mental health issues. They may work in a variety of settings, including schools, hospitals, and private practices. This course may be useful for Mental Health Counselors. It provides a strong foundation in behavioral neuroscience and the study of obsessive-compulsive disorder, which are essential for understanding and treating mental health issues.
Psychiatrist
Psychiatrists diagnose and treat mental health disorders. They may work in a variety of settings, including hospitals, clinics, and private practices. This course may be useful for future Psychiatrists. It provides a strong foundation in behavioral neuroscience and the study of obsessive-compulsive disorder, which are essential for understanding and treating mental health disorders.
Veterinarian
Veterinarians care for and treat animals. They may work in a variety of settings, including private practices, animal shelters, and zoos. This course may be useful for future Veterinarians. It provides a strong foundation in animal behavior and how to care for laboratory mice, which are essential for someone who wants to work with animals.
Animal Behaviorist
Animal Behaviorists study the behavior of non-human animals. They may work in a variety of settings, including zoos, wildlife sanctuaries, and research laboratories. This course may be useful to those interested in becoming an Animal Behaviorist. It provides a strong foundation in animal behavior and how to conduct research on animals.
Ethologist
Ethologists study the behavior of animals in their natural environment. They may work in a variety of settings, including universities, research laboratories, and wildlife sanctuaries. This course may be useful for those who want to become Ethologists. It provides a strong foundation in animal behavior and how to conduct research on animals.
Animal Care Technician
Animal Care Technicians work in a laboratory setting, providing care to and taking samples from animals. This course can help build a foundation for someone looking to become an Animal Care Technician. It teaches responsible conduct of research and care of laboratory mice, which are essential skills for this role.
Research Scientist
Research Scientists conduct research in a variety of fields. They may work in a variety of settings, including universities, research laboratories, and private companies. This course may be useful for future Research Scientists. It provides a strong foundation in conducting research involving mice, which is relevant to a variety of research fields.
Laboratory Animal Technician
Laboratory Animal Technicians care for and maintain laboratory animals. They may also assist with research projects. This course can help build a foundation for someone looking to become a Laboratory Animal Technician. It teaches responsible conduct of research and care of laboratory mice, which are essential skills for this role.
Pharmacologist
Pharmacologists study the effects of drugs on the body. They may work in a variety of settings, including universities, pharmaceutical companies, and hospitals. This course may be useful for future Pharmacologists. Although this course does not cover pharmacology, it does provide a strong foundation in behavioral neuroscience. This knowledge may be useful for someone who wants to pursue a career in Pharmacology.
Biostatistician
Biostatisticians apply statistical methods to biological data. They work in a variety of settings, including hospitals, universities, and pharmaceutical companies. This course may be useful for future Biostatisticians. Although this course does not focus on biostatistics, it does cover the collection and analysis of behavioral data from mice. This experience may be helpful for someone who wants to pursue a career in Biostatistics.
Academic Researcher
Researchers play a pivotal role in advancing our understanding of science and medicine. They dedicate themselves to expanding human knowledge by studying and collecting data. This course may be useful for someone interested in becoming an Academic Researcher. It provides a strong foundation in conducting research involving mice, which is highly relevant to those who may be interested in pursuing research in the field of Behavioral Neuroscience.

Reading list

We've selected six books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Behavioral Neuroscience: Foundations of Compulsive Behaviors.
Provides a comprehensive overview of compulsive behaviors, including their diagnosis, treatment, and neural underpinnings. It valuable resource for clinicians and researchers in the field of psychiatry.
This atlas provides detailed images of the mouse brain, which is essential for researchers who are conducting experiments on mice.
This textbook provides a comprehensive overview of the neurobiology of mental illness. It valuable resource for students and researchers in the field of psychiatry.
Provides a critical overview of the ethical issues surrounding the use of animals in research. It valuable resource for students and researchers who are interested in the ethical implications of animal research.
Provides a comprehensive overview of the current state of animal experimentation. It valuable resource for students and researchers who are interested in the ethical, social, and scientific implications of animal research.
Provides a comprehensive overview of the principles of animal welfare. It valuable resource for students and researchers who are interested in the ethical implications of animal research.

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