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Michael Brandeis and Michal Ramot

This description might sound trivial it is however not at all. Before the appearance of sex, organisms reproduced solely by division. One cell divided into two cells, no partners, no fusion, just simple cell division. This simple cell division is still here. In fact, the trillions of cells that make up your body are all the descendants of a single cell that underwent several dozens of cell divisions. Surprisingly, most multicellular, as well as, many unicellular organisms reproduce by sex. We might take it thus for granted but this course will show you that it is a rather peculiar and enigmatic process.

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This description might sound trivial it is however not at all. Before the appearance of sex, organisms reproduced solely by division. One cell divided into two cells, no partners, no fusion, just simple cell division. This simple cell division is still here. In fact, the trillions of cells that make up your body are all the descendants of a single cell that underwent several dozens of cell divisions. Surprisingly, most multicellular, as well as, many unicellular organisms reproduce by sex. We might take it thus for granted but this course will show you that it is a rather peculiar and enigmatic process.

This course will provide you with the necessary tools to understand how sex works and to marvel at its mysteries. We will start by meeting the actors of this greatest drama in their native habitats, from ancient bacteria that live in thermal geysers in Yellowstone national park to the great mammals that roam the African savanna. We will also briefly discuss the history of life on earth and its contemporary state.

The second unit defines the rules of the game explaining the mechanisms of heredity and evolution.

The third unit focuses on meiosis, the fundamental and conserved molecular event that forms the basis of sex. And that might have led to the appearance of sex in the first place. We will also explain the fertility cycle and male and female germ cell development. The fourth unit describes the striking variability of sex determination throughout the animal kingdom. We will discuss the requirement for two genders and their considerable cost. Finally, we will dive in the gulf of Aqaba to meet organisms that are both male and female either at the same, or at different times.

Sex requires cooperation between two individuals – a male and a female – that are in a basic conflict of interest. Furthermore, males and females compete among themselves. This complex network of cooperation and conflict forms the fascinating plot we will tell in the fifth unit that will discuss the patterns of reproduction and social behavior of different animals – corals, insects, spiders, fish, birds, and mammals. We will be intrigued to discover that the same basic conflict is resolved by a huge range of approaches, from altruistic behavior all the way to open warfare and infanticide.

The sixth unit takes us to fertilization and beyond. Starting at an IVF clinic we follow embryonic development throughout the animal kingdom from insects to tadpoles and humans.

The seventh unit is dedicated to flowering plants that made our world colorful, sweet-smelling and tasty and that produce almost all animal food.

What's inside

Learning objectives

  • This course will provide tools, knowledge and case studies that will enable you to reflect upon and appreciate the mysteries and wonders of sexual reproduction. among other you will learn about:
  • The eukaryotic cell and the animal and plant kingdoms
  • The principles of heredity and evolution
  • The significance of meiosis and how germ cells are generated
  • Sex determination and why there are (usually) two sexes
  • The fundamental female-male conflict and how it shapes form and behavior
  • The basics of embryonal development
  • The influence of plant evolution on animal development and the environment

Syllabus

Week 1 – From the eukaryotic cell to biodiversity
This chapter will start in Yellowstone NP to introduce the compound eukaryotic cell, the basis of all multicellular organisms and of sex. We will visit the natural history museum in Tel Aviv to discuss classification and the concept of species and travel to Africa to witness biodiversity. Finally, we will briefly describe the history of life on earth and ask whether we are in the midst of mass extinction.
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Week 2 – Heredity and evolution
We will describe the three requirements for evolution – variability, selection, and heritability. We will prepare DNA, explain how it encodes information and learn how heredity works. We will meet peacocks and giraffes and discuss sexual selection.
Week 3 – Meiosis and gametogenesis
We will start by describing how cells divide and then learn about meiosis. This fundamental, ancient and conserved process is the basis of all sex as it is required for sex cell production. We will further learn about the fertility cycle and how male and female germ cells are produced.
Week 4 - Male and/or Female
In this chapter we learn about the diverse manner sex is determined and discuss the cost of sex. We will meet hermaphrodite organisms as well as organisms that change their sex during the course of their life. The basic difference between females and males is their sex cells - eggs and sperm. From this difference, many additional differences appeared in various groups leading to sexual dimorphism.
Weeks 5 - Sociality
This chapter will discuss the wide and fascinating range of patterns of reproduction in the animal kingdom. The basic narrative is the conflict between males and females as well as between males and between females. We will meet many different organisms in a variety of locations and discuss examples of external vs. internal fertilization. This is the longest chapter of the course and it will focus among others on social structures in birds, mammals, monkeys, elephants, and even humans.
Week 6 – Embryonal development
This chapter will examine how the fertilized egg develops into an organism in a variety of different animal groups. We will be surprised to observe how highly conserved embryonal development is among very diverse animal groups
Week 7 – Flowers
Flowering plants represent the grandest cooperation in the living world. We will start by learning about primitive plants and their reproduction. We will then learn about flowers and pollinators and how they completely transformed our world. We will conclude with the rather peculiar dual-mode of fertilization in flowers.

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Explores the fundamental and enigmatic process of sexual reproduction, from its origins to its mechanisms
Taught by Michael Brandeis and Michal Ramot, renowned experts in molecular biology and evolutionary genetics
Develops a strong foundation in heredity, evolution, meiosis, sex determination, and embryonal development
Provides tools and case studies for understanding the mysteries and wonders of sexual reproduction
Examines the fascinating range of patterns of reproduction in the animal kingdom, exploring the conflict between males and females
Advises students to take other courses in cell biology and genetics as prerequisites

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Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Sex from molecules to elephants with these activities:
Volunteer at a Science Museum
Apply your knowledge by sharing it with others and fostering a love of science.
Show steps
  • Find a museum to volunteer at
  • Apply for a volunteer position
  • Orientate with the museum staff
  • Develop a plan for your volunteer activities
Find a Mentor in the Field
Connect with an expert in the field for guidance and support throughout your learning journey.
Show steps
  • Identify potential mentors
  • Approach and introduce yourself
  • Build a relationship and seek guidance
Read 'The Greatest Show on Earth'
Deepen your understanding of evolution by reading this highly acclaimed book.
View Science in the Soul on Amazon
Show steps
  • Read the book
  • Take notes on key concepts
  • Discuss the book with others
Six other activities
Expand to see all activities and additional details
Show all nine activities
Explore the National Museum of Natural History
Review the principles of heredity by visiting the museum, which houses a vast collection of exhibits related to the topic.
Show steps
  • Visit the Hall of Human Origins to learn the basis of human evolution
  • Explore the Hall of Biodiversity to gain insight into the diversity of life on Earth
  • Visit the Hall of Mammals to understand the evolution of mammals
Attend a Study Group
Enhance your understanding and retention by discussing course concepts with peers.
Show steps
  • Form a study group with classmates.
  • Choose a topic to discuss
  • Take turns presenting and facilitating the discussion
Develop a Mind Map
Enhance your understanding by creating a visual representation of the course material.
Show steps
  • Start with a central topic
  • Add branches for main ideas
  • Add sub-branches for supporting ideas
Create a Glossary of Key Terms
Enhance your understanding by creating a comprehensive glossary of important terms.
Show steps
  • Start with a list of key terms
  • Define each term accurately
  • Organize the terms alphabetically
Attend a Workshop on Scientific Writing
Improve your ability to communicate scientific concepts effectively.
Show steps
  • Find a writing workshop
  • Prepare for the workshop
  • Attend the workshop
Solve Practice Problems
Strengthen your grasp of concepts by attempting practice problems regularly.
Show steps
  • Access practice problems online
  • Work through the problems
  • Check your answers

Career center

Learners who complete Sex from molecules to elephants will develop knowledge and skills that may be useful to these careers:
Plant Breeder
Plant breeders develop and improve new varieties of plants. They work with a variety of plants, including crops, flowers, and trees. This course will help you understand the fundamentals of plant breeding, which is essential for this field.
Horticulturist
Horticulturists grow and maintain plants for food, medicine, and other purposes. They also design and manage landscapes. This course will help you understand the fundamentals of horticulture, which is essential for this field.
Botanist
Botanists study plants, including their taxonomy, physiology, and ecology. They also study the relationship between plants and animals. This course will help you understand the fundamentals of botany, which is essential for this field.
Animal Nutritionist
Animal nutritionists develop and implement nutrition plans for animals. They work with a variety of animals, including livestock, pets, and laboratory animals. This course will help you understand the fundamentals of animal nutrition, which is essential for this field.
Laboratory Animal Technologist
Laboratory animal technologists care for and maintain animals used in research. They also assist with research procedures. This course will help you understand the fundamentals of laboratory animal care, which is essential for this field.
Animal Caretaker
Animal caretakers provide care for animals in a variety of settings, including zoos, animal shelters, and private homes. This course will help you understand the fundamentals of animal care, which is essential for this field.
Aquaculturist
Aquaculturists raise and harvest fish, shellfish, and other aquatic organisms. They also develop and implement aquaculture techniques. This course will help you understand the fundamentals of aquaculture, which is essential for this field.
Animal Breeder
Animal breeders select and mate animals to improve their traits. They work with a variety of animals, including livestock, pets, and laboratory animals. This course will help you understand the fundamentals of animal breeding, which is essential for this field.
Veterinarian
Veterinarians diagnose, treat, and prevent diseases in animals. They also perform surgeries and provide other medical care. This course will help you understand the fundamentals of animal biology, which is essential for this field.
Conservation Scientist
Conservation scientists study the conservation of wildlife and their habitats. They develop and implement conservation plans to protect endangered species and their ecosystems. This course will help you understand the fundamentals of conservation science, which is essential for this field.
Wildlife Biologist
Wildlife biologists study and manage wildlife populations. This includes studying the behavior, habitat, and conservation of animals. This course will help you understand the fundamentals of animal biology, which is essential for this field.
Wildlife Guide
Wildlife guides lead tours and educate people about wildlife. They also provide information about the environment and conservation. This course will help you understand the fundamentals of wildlife biology, which is essential for this field.
Animal Behaviorist
Animal behaviorists study the behavior of animals, including their social interactions, communication, and learning. This course provides a foundation in animal behavior, which is essential for this field.
Zoologist
Zoologists study animals, their behavior, and how they interact with their environment. They study molecular mechanisms, evolution, genetics, and behavior. Studying Sex from molecules to elephants will help build a foundation for this field of study. This course would also be helpful for individuals interested in careers in animal science, environmental science, and evolutionary biology.
Animal Trainer
Animal trainers train animals to perform specific tasks. They work with a variety of animals, including pets, service animals, and animals used in entertainment. This course will help you understand the fundamentals of animal training, which is essential for this field.

Reading list

We've selected 14 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Sex from molecules to elephants.
Is written by one of the course instructors and provides a comprehensive overview of the evolution of sex from a biological perspective.
Classic in evolutionary biology and explores the evolution of sex from a theoretical perspective, with implications for the understanding of the conflicts and cooperation between males and females.
This textbook provides core concepts in genetics. It recommended read for the unit on heredity and evolution, where the course dives into the principles of heredity and evolution, and the significance of meiosis.
Explores the history of mass extinctions and discusses the current threats to biodiversity.
Explores the evolutionary theory of sexual conflict, which posits that males and females have different reproductive interests that lead to conflict and competition.
This textbook provides a comprehensive overview of developmental biology, from the molecular level to the organismal level. The sixth unit of the course focuses on fertilization and beyond, and this textbook can provide in-depth knowledge about embryonal development in a variety of animal groups.
Explores the implications of evolutionary theory for human behavior, with a focus on sex and gender.
Explores the relationship between plants and humans, and how plants have shaped human culture and history.
Provides a comprehensive overview of the diversity of life on Earth and can serve as a great reference for the part of the curriculum that covers biodiversity.
This textbook provides introductory topics on: * The science of biology * What cells are, cell structure, cell processes * Genetics and evolution * Animal diversity * Plant diversity * Ecology and the biosphere * Human biology This textbook can provide background knowledge for the first unit of the course, covering the eukaryotic cell, the animal and plant kingdoms, and the history of life on earth.
Fascinating exploration of the world of flowers and their relationship with insects and other animals.
This textbook provides an introduction to evolutionary biology and can serve as a great reference for the part of the curriculum that covers the principles of heredity and evolution.

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