Most FutureLearn courses run multiple times. Every run of a course has a set start date but you can join it and work through it after it starts. Find out more This course is designed for scientists and healthcare professionals with an interest in obtaining a postgraduate-level understanding of genomic sequencing technologies. If you are completing both Genomic Technologies in Clinical Diagnostics courses, we recommend that you complete Genomic Technologies in Clinical Diagnostics: Molecular Techniques first. And if you are new to the field, we recommend that before you start either course, you complete The Genomics Era: the Future of Genetics in Medicine – the first in the Genomics in Healthcare program from St George’s. You can use the hashtag #FLgentechNGS to talk about this course on social media.

Topics Covered

• The changing landscape of genomics: From Sanger sequencing to Next Generation Sequencing
• Overview of Next Generation Sequencing platforms and their methodology
• Targeted resequencing
• Alignment, variant calling and annotation
• Other applications of Next Generation Sequencing beyond DNA sequencing
• Next Generation Sequencing in gene discovery
• Gene discovery in the research and diagnostics
• Next Generation Sequencing in clinical diagnostics: Single gene, gene panel sequencing, exome and genome sequencing
• How to design a gene panel
• The 100 000 Genomes project
• The transforming NHS: Genomics in mainstream practice