《基因论》是摩尔根染色体遗传理论的代表之作,包括遗传学的基本原理、遗传粒子理论、染色体与基因、突变性状的起源、染色体畸变等。此书总结了作者及其团队以果蝇为主要实验材料的遗传研究成果,以及自孟德尔遗传定律在1900年被重新发现之后的遗传学研究成果,有助于读者理解遗传学划时代思想的产生和发展过程 。
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