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Antimicrobial resistance - theory and methods

The course will cover the topics related to antimicrobial resistance with basic definitions and overview on antimicrobials their use and the emergence and spread of resistance. The course will guide you through the concepts and the importance of resistance spread and dissemination and how that happens. It will show you how bacteria become resistant and which mechanisms they might use for this. And as part of the course you will also receive some training in methods for antimicrobial susceptibility testing (AST) and detection of specific resistance in the microbiological laboratories with the basic methods available and with focus on the obtention of good quality results which can be interpreted and used for different purposes. Additionally, it will show you how to use genomic analysis tools to analyze whole genome sequencing data to detect resistance genes (and or other genes of interest) in a simple and easy way using online tools freely available. In the new new version an additional module including detection of specific resistance mechanisms was added. After this course you should be able to: 1. Describe the most important families of antimicrobials and mode of action 2. Understand the basic concepts of antimicrobial resistance from several perspectives (clinical, research and microbiological) 3. Enumerate and describe how bacteria can become resistant and the mechanisms that may be involved in that process 4. Describe how antimicrobial resistance emerges and spreads around the world including concepts of antimicrobial resistance transfer, selection and dissemination 5. Enumerate the methods used for antimicrobial susceptibility testing (AST) 6. Compare dilution and diffusion methods and know the basic techniques of agar disk diffusion, broth dilution and agar dilution methods 7. Have detailed theoretical knowledge on how to perform the main methods in a laboratory 8. Know the basic concepts about analysis and interpretation of results of AST, including different breakpoints, cut-off setting and their applications. 9. Understand the importance and related concepts related to quality management and quality assurance method standardization, applied to AST 10. Relate the information obtained in this course with real cases of resistant bacteria spreading in patients, the community, animals or the environment 11. Relate the phenotypical results with results from genotyping using molecular techniques for detection of resistance mechanisms 12. Understand the concept and be able to apply genomic analysis tools used to detect resistance genes and other relevant genes from Whole Genome Sequencing (WGS) data (with demonstration of selected online tools) Disclaimer: Please note that the guidelines and methods referred or links included in these materials are updated when the videos lectures are produced and before the course is released, however these might become outdated with time.

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Rating 4.6 based on 165 ratings
Length 6 weeks
Effort 5 weeks of study, 1-2 hours/week
Starts Jul 3 (42 weeks ago)
Cost $49
From Technical University of Denmark (DTU) via Coursera
Instructors Lina Cavaco, Pimlapas Leekitcharoenphon, Rene S. Hendriksen, Valeria Bortolaia
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Medicine And Healthcare Animals And Veterinary Science Basic Science

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What people are saying

about antimicrobial resistance

i get perfect information about antimicrobial resistance ...thank you Great course, It gave me an overview of antibiotic resistance problems.

This course teach all things that useful and importance for preparing to everyone who want to know about antimicrobial resistance.

Thank You coursera I feal so amazed by all the information, is a complete course and i would like to learn more about antimicrobial resistance.

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lina cavaco

dr lina cavaco is awesome her illustrants and data show helps me greatly in understanding the subject , thanks dr cavaco A well structured course on Antimicrobial Resistance organized by experts in the field.

I want to thank DTU and its associates and Researchers like Lina Cavaco and Dr. Pimlapas is been a great guide and teacher to me.

I really enjoyed learning from Dr Lina Cavaco.

Thank you to DTU especially to Dr. Lina Cavaco for expanding my knowledge about drug resistance and antimicrobial susceptibility testing.

very useful Loved the lectures till Week 4 given by Lina Cavaco.

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so much

Thank you so much for your lectures.

Thank you so much once again and I am hopeful to see this course knowledge strengthening my resume for my future endeavours.

Thank you so much for the class.

Thank you so much for this information and this course Excellent!

Thank you so much for the opportunity.

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really enjoyed

:D I really enjoyed doing this course.

I really enjoyed the course, being a complete novice i found it challenging to understand some of the technical terms but learnt alot.

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learning experience

Muy instructivo It was good learning experience!!

Overall it was a great learning experience!!

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susceptibility testing

I received 2 weeks ago an email requesting my dates for the certification but I havent received it yet Excelente Great course focused on Antimicrobial Testing for microbiologic labs The course is very insightful and offers practical knowledge to antimicrobial susceptibility testing.

Overall, thank you for setting up this course Very important course that help to know several ways of anti microbial susceptibility testing.

know about

It was really a good lectures and please I want to know about my certificate in have already purchased this course and submitted allThe documents let me know when will I get my certificate .

I came to know about many things, all the basic so this course was actually helpful.

learn more

Really helpful if you have anything to do with testing antimicrobial resistance in the lab or if you just want to learn more about the topic.

Thanks to the team at DTU who produced this course and I look forward to taking any further courses in this extremely important area that you pro Excellent content with a rich subject giving us good basis to explore and learn more on the subject and apply the acquired knowledge into many different fields.

case study

For a student of bioinformatics like me, this course is an indepth case study of a single topic.

As such, it is a perfect case study for someone interested in bacterial genetics, Being a microbiology student this course is helping me too much in my field.

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drug resistance

Hoping for more lessons about drug resistance.

It improved my understanding of drug resistance Es un curso interesante, aunque le faltan lecciones que realmente expliquen el trabajo real del laboratorio.

Careers

An overview of related careers and their average salaries in the US. Bars indicate income percentile.

Resident Infectious Diseases Clinical Specialist and Antimicrobial Stewardship Program Manager $67k

Infectious Diseases/Antimicrobial Stewardship Clinical Pharmacist Specialist $201k

Infectious Diseases Clinical Specialist and Antimicrobial Stewardship Program Manager $229k

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Rating 4.6 based on 165 ratings
Length 6 weeks
Effort 5 weeks of study, 1-2 hours/week
Starts Jul 3 (42 weeks ago)
Cost $49
From Technical University of Denmark (DTU) via Coursera
Instructors Lina Cavaco, Pimlapas Leekitcharoenphon, Rene S. Hendriksen, Valeria Bortolaia
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Medicine And Healthcare Animals And Veterinary Science Basic Science

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