Bacterial Genomes
Comparative Genomics using Artemis Comparison Tool (ACT)
Week 1 Week 2 Week 3 Most FutureLearn courses run multiple times. Every run of a course has a set start date but you can join it and work through it after it starts. Find out more This course would benefit those interested in learning how to use tools to investigate and research bacterial genomes, and acquire bioinformatics skills to evaluate the role of microbial genes in disease. Learners will gain experience in comparative genomics, using the Artemis Comparison Tool to probe, visualise and compare genomes, and analyse the results. This course will be of interest to anyone interested in microbiology, including undergraduates, post-graduates, biomedical researchers, microbiologists, bioinformaticians, teachers, and healthcare professionals. The opportunity to gain experience in using the Artemis Comparison Tool, a computational tool designed for comparative genomics, will also be of interest to all those who have studied our pre-requisite courses: those with an interest in genomics and disease outbreaks, teachers and their 16-18-year-old science and computing students. Ideally, you will have completed Bacterial Genomes: From DNA to Protein Function Using Bioinformatics and Bacterial Genomes: Accessing and Analysing Microbial Genome Data before joining the course. You can use the hashtag #FLartemis2act to talk about this course on social media.
Topics Covered- Introduction to comparative genomics
- Introduction to ACT
- Analyse available data
- Generate your own comparison files
- Make your own comparisons in ACT
- Identify pseudogenes in
- using ACT
- Peer review project: Comparative genomics on two clinically relevant plasmids from
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