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Dr. Amy Wesolowski, PhD, Emily Gurley, PhD, MPH, Allison Hill, and Shaun Truelove

Mathematical modeling is an increasingly widespread tool for understanding infectious disease transmission and informing public health decision making. This course provides an in depth overview of the practical uses of mathematical modeling for a range of diseases and scenarios. We cover the basic principles of infectious disease models, how models are adapted to be specific to the disease and question of interest, and important assumptions of different models. We will discuss how data informs models, how models can be used to interpret data, uncertainty in model results, and pros and cons of different modeling and analytic approaches. In each module we focus on a use case for models: evaluating potential control strategies, quantifying and comparing the transmission rate of infections, and for forecasting future disease burden.

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Mathematical modeling is an increasingly widespread tool for understanding infectious disease transmission and informing public health decision making. This course provides an in depth overview of the practical uses of mathematical modeling for a range of diseases and scenarios. We cover the basic principles of infectious disease models, how models are adapted to be specific to the disease and question of interest, and important assumptions of different models. We will discuss how data informs models, how models can be used to interpret data, uncertainty in model results, and pros and cons of different modeling and analytic approaches. In each module we focus on a use case for models: evaluating potential control strategies, quantifying and comparing the transmission rate of infections, and for forecasting future disease burden.

Learners will get the most out of this course if they are familiar with the basics of infectious disease epidemiology and some university level mathematics background. Those who are interested in a more basic overview of model uses in public health decision-making without the requirement for any mathematics background are recommended to view our companion course, Infectious Disease Transmission Models for Decision Makers. Learners who have a stronger quantitative background and are interested in learning to construct models themselves are suggested to consider the Infectious Disease Modeling Specialization developed by Imperial College London.

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What's inside

Syllabus

The Basics of Building Infectious Disease Transmission Models
Inferring Infectious Disease Transmission Rates from Outbreak Data
Prediction of Infectious Disease: Forecasting and Scenario Projection
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Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Teaches advanced students transferable skills used in industry
Suitable for students with intermediate epidemiology knowledge
Demonstrates broad industry applications of mathematical disease modeling
Requires learners to come in with introductory university-level math

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Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Infectious Disease Modeling in Practice with these activities:
Support Disease Surveillance and Response Efforts
Gain practical experience in disease surveillance and response activities.
Show steps
  • Contact local health agencies or non-profit organizations.
  • Inquire about volunteer opportunities related to disease surveillance or outbreak response.
  • Participate in data collection, outreach, or other support activities.
Mathematical Models in Epidemiology
Expand your understanding of the mathematical foundations of infectious disease modeling.
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  • Read chapters related to the topics covered in the course.
  • Work through the exercises and problems in the book.
Learn R for Infectious Disease Modeling
Gain proficiency in using R for analyzing infectious disease data and building models.
Browse courses on R Programming
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  • Find online tutorials or courses on using R for infectious disease modeling.
  • Follow the tutorials and complete the exercises.
  • Apply R to analyze real-world infectious disease data.
Four other activities
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Discuss Model Assumptions and Limitations
Participate in discussions to critically evaluate the assumptions and limitations of infectious disease models.
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  • Join online forums or discussion groups.
  • Read and respond to posts related to model assumptions and limitations.
  • Share your own insights and experiences.
Attend Workshop on Advanced Infectious Disease Modeling Techniques
Enhance your knowledge and skills through a workshop focused on advanced infectious disease modeling techniques.
Show steps
  • Research and identify relevant workshops.
  • Register and participate in the workshop.
  • Apply the techniques learned to your own research or projects.
Model COVID-19 Vaccination Effectiveness
Build a mathematical model to simulate the spread of COVID-19 and evaluate different vaccination strategies.
Browse courses on COVID-19
Show steps
  • Gather data on COVID-19 transmission rates and vaccination rates.
  • Build a mathematical model that incorporates transmission rates, vaccination rates, and other relevant factors.
  • Run simulations to evaluate the effectiveness of different vaccination strategies.
  • Analyze the results and make recommendations based on the model's predictions.
Develop a Forecasting Model for Your Local Community
Apply your knowledge of infectious disease modeling to create a model that can forecast disease outbreaks in your local community.
Browse courses on Infectious Disease
Show steps
  • Gather data on infectious disease cases in your community.
  • Build a mathematical model to forecast future outbreaks.
  • Validate your model using historical data.
  • Present your findings to local health officials.

Career center

Learners who complete Infectious Disease Modeling in Practice will develop knowledge and skills that may be useful to these careers:
Infectious Disease Modeler
As an Infectious Disease Modeler, you will use mathematical models to understand the transmission of infectious diseases. This course will provide you with the skills and knowledge you need to be successful in this role. You will learn about the basic principles of infectious disease models, how models are adapted to be specific to the disease and question of interest, and important assumptions of different models.
Public Health Analyst
Public Health Analysts use data to improve the health of populations. This course can help you develop skills in infectious disease modeling, which is an important tool for understanding the spread of disease and developing effective public health interventions. The knowledge you gain from this course will be valuable in your role as a Public Health Analyst.
Public Health Advocate
Public Health Advocates work to improve the health of communities by promoting healthy behaviors and policies. Infectious disease modeling is a useful tool for understanding the spread of disease and developing effective public health interventions. This course can help you build a foundation in the principles of infectious disease modeling, which will be helpful in your career as a Public Health Advocate. The knowledge you gain from this course will help you to be a more effective advocate for policies that promote public health.
Public Health Policy Analyst
Public Health Policy Analysts develop and evaluate public health policies. Infectious disease modeling is a useful tool for understanding the impact of public health policies. This course will help you develop a solid understanding of the principles of infectious disease modeling, which will be helpful in your career as a Public Health Policy Analyst.
Health Communications Specialist
Health Communications Specialists develop and implement communication campaigns to promote public health. Infectious disease modeling is a useful tool for understanding the spread of disease and developing effective public health interventions. This course can help you build a foundation in the principles of infectious disease modeling, which will be helpful in your career as a Health Communications Specialist. The knowledge you gain from this course will help you to develop more effective communication campaigns that promote public health.
Disease Ecologist
Disease Ecologists study the relationships between infectious diseases and the environment. This course can help you build a foundation in infectious disease modeling, which is a useful tool for understanding the spread of disease in different environments. The models you'll learn about in this course can be applied to a variety of disease ecology topics, such as the spread of vector-borne diseases and the impact of climate change on disease transmission.
Epidemiologist
Working as an Epidemiologist, you will investigate and track the spread of infectious diseases. This course can help you build a foundation in infectious disease modeling, which is a crucial skill for understanding the dynamics of disease transmission. The models you'll learn about in this course can be applied to a variety of epidemiological investigations, such as outbreak investigations and disease surveillance.
Data Scientist
Data Scientists use data to solve problems and make predictions. Infectious disease modeling is one area where Data Scientists can use their skills to improve public health. The models you'll learn about in this course will help you develop a strong foundation in the principles of infectious disease modeling, which will be helpful in your career as a Data Scientist.
Biostatistician
As a Biostatistician, you will use statistical methods to solve problems in the biomedical sciences. Infectious disease modeling is one area where biostatisticians can use their skills to improve public health. This course provides a solid foundation in the principles of infectious disease modeling, which will be helpful for your career as a Biostatistician.
Science Educator
Science Educators develop and deliver educational programs that teach students about science. This course can help you build a foundation in infectious disease modeling, which is a complex and rapidly evolving field. The knowledge you gain from this course will help you to develop engaging and informative educational programs that teach students about infectious diseases and their impact on public health.
Health Economist
Health Economists use economic principles to improve the efficiency and effectiveness of health care systems. This course can help you build a foundation in infectious disease modeling, which will be helpful in your career as a Health Economist. The models you'll learn about in this course can be applied to a variety of health economics topics, such as cost-effectiveness analysis and resource allocation.
Clinical Research Scientist
Clinical Research Scientists design and conduct clinical trials to test new drugs and treatments for infectious diseases. This course can help you build a foundation in infectious disease modeling, which is a useful tool for understanding the design and analysis of clinical trials. The models you'll learn about in this course can be applied to a variety of clinical research topics, such as the development of new vaccines and the evaluation of new treatments.
Science Writer
Science Writers communicate complex scientific information to a general audience. Infectious disease modeling is a complex and rapidly evolving field. This course can help you build a foundation in the principles of infectious disease modeling, which will help you to communicate this information to a general audience clearly and accurately. The knowledge you gain from this course will be valuable in your career as a Science Writer.
Pharmaceutical Sales Representative
Pharmaceutical Sales Representatives sell drugs and medical devices to healthcare providers. This course can help you build a foundation in infectious disease modeling, which can be useful in understanding the clinical and economic benefits of different drugs and devices. The knowledge you gain from this course will help you better communicate the value of your products to healthcare providers.
Health Scientist
As a Health Scientist, you will have a hand in improving public health by designing, implementing, and evaluating programs and policies. This course may be useful in helping you better understand the transmission of infectious diseases, which is a major public health concern. The ability to use mathematical modeling to inform your decisions will give you an advantage in this role.

Reading list

We've selected 12 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Infectious Disease Modeling in Practice.
Provides a comprehensive overview of mathematical epidemiology of infectious diseases. It is helpful for understanding the mathematical principles of infectious disease modeling and how to build, analyze, and interpret mathematical models of infectious diseases.
Provides a comprehensive overview of the social determinants of health. It valuable resource for students and researchers who are interested in understanding the role of social factors in health and disease.
Provides a comprehensive overview of the principles of global health. It valuable resource for students and researchers who are interested in understanding the health challenges faced by people around the world.
Provides a gentle introduction to the mathematical models used to study the transmission of infectious diseases. It valuable resource for students and researchers who are new to the field of infectious disease modeling.
Provides a comprehensive overview of Bayesian data analysis. It is helpful for understanding how to use Bayesian methods to analyze data from infectious disease studies.
Provides a practical guide to using Bayesian methods for modeling real-world data. It is helpful for understanding how to use Bayesian models to analyze data from infectious disease studies.
Provides a practical guide to using the R programming language for data science. It is helpful for understanding how to use R to analyze data from infectious disease studies.
Provides a general overview of mathematical modeling in biology. It is helpful for understanding the basic principles of mathematical modeling, which can be applied to infectious disease modeling.
Provides a comprehensive overview of the statistical methods used in epidemiology, including the design and conduct of epidemiologic studies, the analysis and interpretation of data, and the application of statistical methods to public health practice.
While not specifically focused on infectious disease modeling, this textbook provides a solid foundation in population ecology, including topics such as population growth, competition, and predator-prey interactions. These concepts are essential for understanding the dynamics of infectious diseases.
While not specifically focused on infectious disease modeling, this textbook provides a comprehensive overview of cellular and molecular immunology, which is essential for understanding the immune response to infectious diseases.

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