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Gregory Kowalczyk

This course covers most of the basics of a first semester Organic Chemistry course that one might take as a nursing student, science major or pre-med student.  Ideally, students should have taken a year of General Chemistry as a prerequisite, although just completing first semester of General Chemistry should be sufficient. 

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This course covers most of the basics of a first semester Organic Chemistry course that one might take as a nursing student, science major or pre-med student.  Ideally, students should have taken a year of General Chemistry as a prerequisite, although just completing first semester of General Chemistry should be sufficient. 

Students in this course have access to ample supplemental material, all of which will be found in the Resource Folders. In addition to the 18.5 hours of lectures, downloadable audio mp3 files of each lecture are included. For nearly all lectures, a Practice Assignment where you can test your understanding of the material can be found in the Resource Folder. Also included is an answer key for each Practice Assignment. Any graphs, figures or tables presented in the lectures are also available as downloadable files. The content of this course is as extensive as both of my General Chemistry courses that are also available on Udemy.

This course assumes that you have completed General Chemistry I and ideally General Chemistry II college courses. While you will not need to be familiar with all topics covered in those courses, you should have a good understanding of atomic structure, electron configuration, covalent bonding, electronegativity, Lewis Dot Structures, molecular geometry and hybridization. Being familiar with acid-base chemistry and equilibrium as it applies to acids and bases is a plus. Section 2 of this course gives a review of key General Chemistry topics needed for Organic Chemistry.  Since this course covers only the basics of Organic Chemistry, spectroscopic techniques such as Infrared Spectroscopy, Chromatography and Nuclear Magnetic Resonance are not covered. Anyone who is interested in learning about various aspects of Organic Chemistry may find this course beneficial, especially if you had no prior exposure to Organic Chemistry in your studies.

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What's inside

Learning objectives

  • The basic topics of organic chemistry are covered in this course.
  • Each topic is covered in detail with examples and practice assignments for each lecture.
  • Introduction to organic chemistry
  • A review of chemical bonding, atomic structure, electron configurations, lewis dot structures, molecular geometry and hybridization.
  • The alkanes: nomenclature, structural isomerism, cyclic alkanes and their stability, conformational isomerism, physical and chemical properties.
  • The alkenes and alkynes: nomenclature including cis-trans and e-z naming systems, determining units of unsaturation, polymers, physical and chemical properties.
  • Aromatic compounds: benzene derivatives, nomenclature, chemical properties and orientation of substitution.
  • Chirality: stereoisomerism with one, more than one and similar chiral carbon atoms , enantiomer, measurement of optical activity, r and s designations.
  • Alcohols, phenols, ethers and thiols: their nomenclature, physical and chemical properties, polyhydric and unsaturated alcohols.
  • Amines: their structure and nomenclature, physical properties, their basicity and heterocyclic amines.
  • Aldehydes and ketones: structure, nomenclature, physical properties. oxidation and reduction reactions, keto-enol tautomerism.
  • Carboxylic acids: structure and nomenclature, physical properties, acidity, properties and nomenclature of carboxylic acid salts.
  • Carboxylic acid derivatives: nomenclature, physical properties, preparation and reactions of esters, acid halides, anhydrides and amides.
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Syllabus

Aromatic Compounds
Introduction

In this lecture we define Organic Chemistry and show what makes it different from other areas of Chemistry.  We also look at the Carbon cycle in the environment.

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The atomic number is defined and electron orbitals are discussed with respect to their energy levels and shapes.

The relationship between the electron configuration of the atoms and the Periodic Table is explained.  The Octet Rule is introduced.

The two types of chemical bonding, ionic and covalent, are defined with examples given.

The method of representing valence electrons using dot structures is presented.  Simple molecules are used as examples.  The HONC rule is given and explained.

This lecture instructs you on how to draw Lewis Dot Structures for compounds with double or triple bonds.

In this lecture hybridization and bond angles are described for carbon, and to a lesser extent, nitrogen and oxygen.  Sigma and pi bonds are defined.  A summary sheet is given and discussed.

Hydrocarbons are defined and the four families that make up hydrocarbons, alkanes, alkenes, alkynes and aromatics are presented.  Distinction is made between saturated and unsaturated compounds.

The three types of alkanes are listed and the first ten straight-chain alkanes are discussed with respect to their names, structural formulas and line-angle formulas

Structural isomerism is defined and several examples are given.  The importance of structural formulas over molecular formulas for organic compounds is discussed.

Cyclic alkanes are introduced, named and it was shown how isomers of these compounds are made.

In this lecture the names of the straight-chain and branched alkyl groups are given.

The rules are given for naming branched alkanes.  Several examples are given.

Nomenclature rules for naming alkanes when halogens are substituents are explained with several examples given.

Rules for naming cyclic alkanes with substituents present on the ring are given along with several examples.

Stereoisomerism is introduced and defined as it relates to di-substituted cyclic alkanes.

Conformational isomerism is explained, ethane and 1,2 dibromoethane are used as an examples.

The stability of cyclic alkanes is assessed based on ring strain of the structure.  For larger cyclic alkanes, it is shown how the more stable conformational isomer can be determined.

The physical properties of melting point, boiling point, density and solubility of alkanes is discussed.  The process of fractional distillation of crude oil to isolate different groups of alkanes is briefly described.

The two types of chemical reactions for alkanes, combustion and substitution are presented.

Alkenes and alkynes are defined as unsaturated hydrocarbons and units of unsaturation with respect to alkanes, alkenes and alkynes is discussed.

The rules for naming alkenes and alkynes are explained.

Cis-trans isomerism is discussed with its application to alkenes.  Rules for nomenclature are explained.

The E-Z System of naming geometric isomers when cis-trans doesn't work is explained.

Units of unsaturation is discussed as it relates to isomerism.

The physical properties of alkenes and alkynes are presented.

Some of the basic types of reactions of alkenes is discussed.  The Markovnikov rule is introduced.

This lecture shows how alkenes can react to form polymers and copolymers.  Reaction mechanisms are shown for two types of polymerization reactions.

The chemical reactions of alkynes are discussed.

This lecture focuses on the structure of benzene with respect to the degree of unsaturation.

Several benzene derivatives were named, polycyclic aromatic hydrocarbons were introduced as well as several aryl groups.

Nomenclature rules for naming mono-di- and multi-substituted benzene derivatives are given with examples.

The four basic types of reactions with aromatic compounds are discussed and explained: halogenation, nitration, sulfonation and alkylation.

The position of electrophiles substituted onto benzene derivatives is explained.  Activating and deactivating groups are defined and shown how they determine the orientation of the product. 

In this lecture we discuss what is required of a molecule for it to have a non-superimposable mirror image.

Properties on enantiomers are discussed in this lecture.

In this lecture we show how to represent stereoisomers in 3 dimensions using wedges and dashes for bonds.  Fisher projections are also introduced.

Two methods of determining whether two configurations are enantiomers or identical molecules are explained.

In this lecture we explain how the optical activity of a compound is detected and measured and the term specific rotation is defined.

Stereoisomerism of compounds with two chiral carbon atoms is discussed.

Stereoisomers of molecules with two similar carbon atoms give rise to meso compounds.  Under what conditions this occurs is explained in this lecture.

In this lecture we see that chiral cyclic compounds can have enantiomers, diastereomers and can also exist as meso compounds, depending on their structure.

The procedure for assigning R and S configurations to chiral molecules is given.

In this lecture some chemical reactions are presented that show under what conditions stereoisomers can form from chemical reactions.

Some of the common functional groups are introduced.

The classifications for alcohols are explained and rules for naming alcohols are presented.

In this lecture we discuss alcohols with more than one hydroxyl group including nomenclature.

The physical properties of solubility and boiling point of alcohols are discussed.

Four different chemical reactions are shown for the preparation of alcohols.

A review of acid-base chemistry, pKa defined, Lewis acids and bases defined and acidity of alcohols assessed.

The dehydration and oxidation reactions of alcohols are explained.

Nomenclature rules are given for naming phenols.  Some phenols that occur in nature are presented.

Solubility, boiling points and acidity of phenols are discussed.

Structure and rules for naming ethers are presented.

Solubility and boiling point trends for ethers are discussed as well as comparisons with alcohols and alkanes.

The nomenclature and chemistry of thiols and sulfides (thioethers) are presented.

The structure of primary, secondary and tertiary amines is presented. 

Rules for naming amines are given.

The solubility and boiling points of amines are examined.

The base strength of amines is explained in terms of electron withdrawing and electron releasing groups.

Heterocyclic amines are introduced and their basicity is discussed.

The structures of families with the carbonyl group are introduced.

The nomenclature rules for aldehydes and ketones are explained.

Trends in boiling points and solubility are discussed within these groups and compared with alkanes and alcohols.

A few important aldehydes and ketones used in industry are presented.

Oxidation of aldehydes and ketones is discussed as well as the Tollen's Test and the Benedict's test used to verify the presence of an aldehyde.

Several addition reactions of aldehydes and ketones are shown.

The keto and enol forms of aldehydes and ketones are explained.

The structure of carboxylic acids is given and the common names of some common acids.

Rules for naming carboxylic acids are explained.

Boiling Points and Solubility of Carboxylic Acids are examined.

Carboxylic acids are discussed with respect to resonance and strengths determined by electron withdrawing and electron releasing groups.

The rules for naming salts of carboxylic acids are discussed and solubility issues of acids are addressed.

The structures and nomenclature rules for four carboxylic acid derivatives are given.

Boiling points and solubility of the four carboxylic acid derivatives and discussed and comparisons between the families are made.

This lecture summarizes the preparation reactions of these acid derivatives as well as common reaction that these derivatives undergo.

Traffic lights

Read about what's good
what should give you pause
and possible dealbreakers
Reviews chemical bonding, atomic structure, and molecular geometry, which are foundational concepts for students pursuing careers in healthcare and the sciences
Includes practice assignments and answer keys, which allows learners to assess their understanding and reinforce key concepts in organic chemistry
Requires prior completion of General Chemistry I and ideally General Chemistry II, which may pose a barrier to entry for some learners
Does not cover spectroscopic techniques, such as Infrared Spectroscopy and Nuclear Magnetic Resonance, which are important tools in organic chemistry
Provides downloadable audio mp3 files of each lecture, which caters to auditory learners and allows for convenient review of the material
Covers topics such as nomenclature, structural isomerism, and chemical properties of alkanes, alkenes, alkynes, and aromatic compounds, which are core concepts in organic chemistry

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Reviews summary

Clear introductory organic chemistry basics

According to learners, this course offers a solid foundation in introductory organic chemistry, essential for students pursuing science, pre-med, or nursing. Many find Dr. K's explanations to be exceptionally clear and easy to follow, making complex topics digestible. The included practice problems are highlighted as crucial for reinforcing understanding. While the course covers the core concepts well for a first semester, some reviewers note that a strong prior background in general chemistry is necessary. It's seen as excellent preparation for university courses or exams like the MCAT, though it does not cover advanced topics like spectroscopy.
Covers intro basics, but not advanced topics.
"This is strictly an introductory course. It doesn't go into detail on things like spectroscopy (NMR, IR)."
"Excellent for first-semester O-Chem basics, but you'll need other resources for advanced topics."
"As advertised, it covers the fundamentals well, but don't expect labs or deep dives into analysis techniques."
"Sufficient for an initial overview, but a university course will cover more depth and practical applications."
"Great for understanding the 'what' and 'why' of basic reactions but stops before instrumental methods."
Requires solid prior Gen Chem knowledge.
"Make sure your general chemistry is strong before taking this. It really builds on those basics."
"I struggled a bit because my Gen Chem II wasn't recent. A good review beforehand is crucial."
"The course assumes you are comfortable with topics like bonding, Lewis structures, and hybridization."
"Having a solid background in General Chemistry is definitely a prerequisite for success."
"Came in with weak Gen Chem, and it made parts of this course challenging initially."
Provides a good base for future study.
"This course gave me a fantastic foundation for my university organic chemistry class."
"Excellent intro to the subject. It covers all the basic topics needed for a first semester."
"I feel much more prepared for OChem now thanks to this course's thorough introduction."
"It's a great starting point for anyone new to organic chemistry."
"Provided a solid understanding of the fundamental principles."
Assignments reinforce learning effectively.
"The practice assignments are essential! Doing them helped me solidify my understanding of each lecture."
"I highly recommend doing all the practice problems. They were directly applicable to understanding the material."
"The exercises after each lecture were key for me to test my knowledge and learn."
"Without the practice problems, I wouldn't have retained nearly as much information."
"The practice assignments really helped reinforce the concepts taught in the videos."
Lectures are clear and easy to understand.
"Dr. K does an amazing job explaining the concepts. Everything was very clear and easy to understand, building block by block."
"The lectures are very clear and concise. Dr. K breaks down complicated ideas into manageable parts."
"I found Dr. K's teaching style to be excellent. He simplifies complex topics so well."
"The way Dr. K explains mechanisms makes them finally click for me."
"Everything was explained very clearly and I could follow along easily."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Dr. K's Introductory Organic Chemistry with these activities:
Review General Chemistry Concepts
Reinforce your understanding of fundamental chemistry principles. This will provide a solid foundation for grasping organic chemistry concepts.
Browse courses on General Chemistry
Show steps
  • Review your notes and textbook from General Chemistry.
  • Work through practice problems on chemical bonding and structure.
  • Focus on topics like Lewis structures and VSEPR theory.
Build a Molecular Model Kit
Visualize organic molecules in three dimensions. This will improve your understanding of stereochemistry and conformational analysis.
Show steps
  • Purchase a molecular model kit or gather materials to build your own.
  • Build models of various organic molecules covered in the course.
  • Use the models to explore stereoisomerism and conformational isomerism.
Read "Organic Chemistry" by Paula Yurkanis Bruice
Supplement the course material with a widely respected organic chemistry textbook. This will provide additional explanations and examples.
View Melania on Amazon
Show steps
  • Obtain a copy of "Organic Chemistry" by Paula Yurkanis Bruice.
  • Read the chapters corresponding to the course syllabus.
  • Work through the example problems and end-of-chapter exercises.
Four other activities
Expand to see all activities and additional details
Show all seven activities
Nomenclature Practice
Solidify your understanding of organic nomenclature. This will enable you to correctly name and identify organic compounds.
Show steps
  • Find online resources or textbooks with nomenclature practice problems.
  • Work through a set of problems, focusing on alkanes, alkenes, and alkynes.
  • Check your answers and review the nomenclature rules for any mistakes.
Create Flashcards for Reactions
Memorize key organic reactions and reagents. This will help you predict reaction products and understand reaction mechanisms.
Show steps
  • Identify the most important reactions covered in the course.
  • Create flashcards with the reaction name on one side and the reactants, reagents, and products on the other.
  • Review the flashcards regularly to reinforce your memory.
Refer to "Organic Chemistry as a Second Language" by David R. Klein
Gain a different perspective on challenging topics. This book offers a simplified approach to organic chemistry concepts.
Show steps
  • Obtain a copy of "Organic Chemistry as a Second Language" by David R. Klein.
  • Read the chapters corresponding to the course syllabus.
  • Work through the example problems and quizzes.
Tutor a Classmate
Reinforce your understanding by explaining concepts to others. Teaching is a great way to solidify your knowledge.
Show steps
  • Offer to tutor a classmate who is struggling with the material.
  • Prepare explanations and examples for the topics they find difficult.
  • Answer their questions and provide feedback on their work.

Career center

Learners who complete Dr. K's Introductory Organic Chemistry will develop knowledge and skills that may be useful to these careers:
Research Scientist
A research scientist in the field of chemistry often designs and conducts experiments, analyzes data, and develops new materials or processes. This course helps build a foundation in organic chemistry, equipping a research scientist with a solid understanding of molecular structures, reactions, and properties which are fundamental to the design and interpretation of experiments. For a research scientist, this course will be particularly useful in interpreting research results that deal with organic molecules and reactions. The course’s coverage of topics, including bonding, nomenclature, and functional groups, may be of immense value to one who wishes to enter this field.
Medicinal Chemist
Medicinal chemists are responsible for designing and synthesizing new pharmaceutical compounds by leveraging their knowledge of organic chemistry. This course may be useful in providing a thorough introduction to organic chemistry, which is essential for understanding the structure, reactivity, and properties of drug molecules. A medicinal chemist uses their understanding of functional groups, stereochemistry, and chemical reactions, all of which are covered in this course, to create molecules that will ultimately become therapeutic. This course’s deep dive into organic nomenclature, bonding, and reaction mechanisms may be particularly relevant to a medicinal chemist.
Pharmacologist
Pharmacologists study how drugs interact with biological systems and are largely involved in the discovery and development of new therapeutics. This course introduces organic chemistry, which is vital for understanding the structures and properties of drug molecules. A pharmacologist applies their understanding of organic compounds to the study of drug action and metabolism. This course, with its detailed coverage of nomenclature, functional groups, and major types of organic reactions, may be especially useful for one who wishes to become a pharmacologist.
Chemical Engineer
Chemical engineers use chemistry, mathematics, and engineering principles to design and develop chemical processes in a variety of industries. This course helps build a foundation in organic chemistry, which is useful to a chemical engineer for understanding the molecular aspects of chemical reactions and material properties. A chemical engineer may use their knowledge of organic chemistry, as taught in this course, to perform tasks such as designing reactors and separation processes. This course's focus on nomenclature, functional groups, and chemical reactions may be especially useful for a chemical engineer.
Biochemist
A biochemist studies the chemical processes that occur in living organisms. This course introduces many fundamental concepts in organic chemistry that form the basis of biochemistry, such as the structure and function of organic molecules, reactions, and major functional groups. A biochemist should be familiar with the organic compounds that comprise life as this course covers. The course’s in-depth discussion of bonding, stereochemistry, and nomenclature may be particularly useful for someone working as a biochemist.
Materials Scientist
Materials scientists investigate the properties and structures of materials and develop new materials with specific characteristics. This course introduces core ideas in organic chemistry that are useful to understanding the structure and behavior of organic materials such as polymers. Many material scientists work with substances like plastics and composites, so this course may be useful in understanding their properties on a molecular level. This course's detailed review of bonding, isomerism, and nomenclature could be especially relevant to a materials scientist.
Toxicologist
Toxicologists study the adverse effects of chemicals on living organisms and investigate the mechanisms of toxicity. This course may be useful as it provides foundational knowledge of organic chemistry, which is essential for understanding the structure and reactivity of toxic compounds. A toxicologist needs to understand how organic molecules interact with biological systems. This course will help build a foundation in organic chemistry, with topics such as chemical bonding, functional groups, and nomenclature. A toxicologist may find the study of structure and reactivity of organic compounds particularly important.
Environmental Chemist
Environmental chemists study the impact of chemicals on the environment, including the fate and transport of organic pollutants. This course may be useful in providing the foundational knowledge of organic chemistry needed to understand the structure and reactivity of organic pollutants. An environmental chemist uses their expertise in organic chemistry to assess and mitigate pollution risks. This course's coverage of major functional groups, bonding, and reactions may be particularly relevant to one working as an environmental chemist.
Science Educator
Science educators teach scientific concepts to students at various levels. This course may be useful for a science educator who teaches chemistry. It provides a thorough overview of organic chemistry principles, which are central to many chemistry courses. A science educator may also use the downloadable content provided by the course to help develop teaching materials. The course's coverage of many topics within organic chemistry could give a science educator the needed expertise to effectively teach and communicate the subject matter to students.
Cosmetic Chemist
Cosmetic chemists create and formulate personal care products using their expertise in organic chemistry. This course may be useful as a way to build a foundational understanding of the organic molecules used in cosmetics, including emollients, surfactants, and preservatives. A cosmetic chemist must understand the properties, reactivity, and interactions of these organic components. This course's overview of functional groups, nomenclature, and reactions of organic molecules may be particularly helpful to someone working in this field.
Patent Attorney
A patent attorney specializes in intellectual property law, particularly the legal aspects of scientific discoveries and inventions. This course may be useful for a patent attorney focusing on chemical or pharmaceutical inventions, giving them the fundamental knowledge of organic chemistry. A patent attorney may need a solid grasp of organic chemical structures and processes to assess the novelty and non-obviousness of a patent application. The course's focus on nomenclature, structure, and properties of organic compounds may be particularly useful to a patent attorney.
Food Scientist
Food scientists study the chemical, physical, and biological properties of food. This course may be useful in giving a strong foundation in the organic compounds that make up food, such as carbohydrates, lipids, and proteins. A food scientist uses organic chemistry knowledge for things like sensory analysis, food processing, and preservation. The course's detailed content on nomenclature, functional groups, and structural isomerism could help a food scientist understand how different processing conditions will affect a food's chemical components.
Laboratory Technician
Laboratory technicians work in research, testing, and quality control. This course may be useful as it provides the fundamental knowledge of organic chemistry needed to work in a chemical lab. A laboratory technician often performs experiments, prepares samples, and analyzes data, often using the techniques discussed in this course. While the course does not discuss spectroscopic techniques, it does discuss the structures and properties of molecules, which could help in the work of a laboratory technician.
Science Writer
Science writers communicate complex scientific findings to the public through various mediums. This course may be useful for a science writer who needs a baseline knowledge of organic chemistry to accurately report on scientific developments in that field. A science writer must understand the fundamentals of organic chemistry in order to convey information about the molecular world to a non-technical audience. This course, which covers nomenclature, bonding, and isomerism, may be useful in translating advanced concepts of organic chemistry to the public.
Physician Assistant
Physician assistants practice medicine under the supervision of a physician. This course may be useful for a physician assistant as it introduces them to the foundational principles of organic chemistry that are relevant to medicine, such as drug structures. A physician assistant must be familiar with the structure and properties of organic compounds, as many drugs are organic molecules. Topics covered by this course, such as bonding, nomenclature, and functional groups, may be particularly useful for a physician assistant.

Reading list

We've selected two books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Dr. K's Introductory Organic Chemistry.
Is designed to help students who struggle with organic chemistry. It presents the material in a clear, concise, and easy-to-understand manner. It focuses on the key concepts and skills needed to succeed in organic chemistry. This book is particularly helpful for students who need additional support and clarification.

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