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تحليل المجموعات الهرمية باستخدام المسافات الإقليدية

Usama A. F. Khalil

بنهاية هذا المشروع ، ستنشئ برنامج Python باستخدام واجهة jupyter لتحليل مجموعة من الفيروسات وترسم مخططًا شجرياً أو دندوجرام بناءً على أوجه التشابه فيما بينها. سيعتمد الدندوجرام الذي ستقوم بإنشائه على ملف تعريف الانحراف التراكمي، والذي يعتمد بدوره على تركيبة النوكليوتيدات. ستستخدم تسلسل الجينوم الكامل للعديد من الفيروسات بما في ذلك، كورونا، وفيروس السارس، وفيروس نقص المناعة البشرية، وزيكا، وحمى الضنك، والفيروس المعوي، وفيروسات غرب النيل.

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بنهاية هذا المشروع ، ستنشئ برنامج Python باستخدام واجهة jupyter لتحليل مجموعة من الفيروسات وترسم مخططًا شجرياً أو دندوجرام بناءً على أوجه التشابه فيما بينها. سيعتمد الدندوجرام الذي ستقوم بإنشائه على ملف تعريف الانحراف التراكمي، والذي يعتمد بدوره على تركيبة النوكليوتيدات. ستستخدم تسلسل الجينوم الكامل للعديد من الفيروسات بما في ذلك، كورونا، وفيروس السارس، وفيروس نقص المناعة البشرية، وزيكا، وحمى الضنك، والفيروس المعوي، وفيروسات غرب النيل.

ملاحظة: تعمل هذه الدورة التدريبية بشكل أفضل للمتعلمين المقيمين في منطقة أمريكا الشمالية. نعمل حاليًا على توفير نفس التجربة في مناطق أخرى.

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Syllabus

تحليل المجموعات الهرمية باستخدام المسافات الإقليدية
للبدء، أوصي بأخذ بضع دقائق لاستكشاف موقع الدورة التدريبية. راجع المواد التي سنغطيها أثناء المشروع، وعاين المهام التي ستحتاج لإكمالها لاجتياز الدورة التدريبية. انقر فوق المناقشات لرؤية المنتديات حيث يمكنك مناقشة مواد الدورة التدريبية مع زملائك الطلاب الذين يحضرون الفصل. بنهاية هذا المشروع، ستنشئ برنامج Python باستخدام واجهة jupyter لتحليل مجموعة من الفيروسات وترسم مخططًا شجرياً dendrogram بناءً على أوجه التشابه فيما بينها. سيعتمد المخطط الذي ستقوم بإنشائه على ملف تعريف الانحراف التراكمي، والذي يعتمد بدوره على تركيب الجينوم من النوكليوتيدات. ستستخدم تسلسل الجينوم الكامل للعديد من الفيروسات بما في ذلك، كورونا ، وفيروس السارس، وفيروس نقص المناعة البشرية، وزيكا، وحمى الضنك، والفيروس المعوي، وفيروسات غرب النيل. إذا كانت لديك أسئلة حول محتوى الدورة التدريبية، فيرجى نشرها في المنتديات للحصول على المساعدة من الآخرين في مجتمع الدورة التدريبية. بالنسبة للمشكلات الفنية المتعلقة بمنصة كورسيرا، قم بزيارة مركز مساعدة المتعلم. حظًا سعيدًا عند البدء وأتمنى أن تستمتع بالدورة!

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Fortifies existing skills for enthusiasts or students who use Python to explore the natural world around them
Involves Python, which is established in biology
Covers dendrograms, which are relevant in genetics and bioinformatics
Exploration of cumulative deviation profiles, which are indispensable in genome sequencing
Presents hands-on labs and interactive materials, catering to various learning styles
Taught by Usama A. F. Khalil, who has authored publications in the field of computational biology

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Career center

Learners who complete تحليل المجموعات الهرمية باستخدام المسافات الإقليدية will develop knowledge and skills that may be useful to these careers:
Bioinformatician
Bioinformaticians use computational tools to analyze biological data. The course will provide you with a foundation in bioinformatics, data analysis, and programming, which are essential skills for bioinformaticians. The knowledge and skills gained in the course will be directly applicable to your role as you work to develop new methods for analyzing biological data.
Virologist
Virologists study viruses, including their structure, function, and evolution. The course will help you develop a foundation in bioinformatics and data analysis, which are essential skills for virologists. The knowledge and skills gained in the course will be directly applicable to your role as you work to study viruses and develop new treatments for viral diseases.
Computational Biologist
Computational biologists use computational tools to study biological systems. The course will provide you with a foundation in bioinformatics, data analysis, and programming, which are essential skills for computational biologists. The knowledge and skills gained in the course will be directly applicable to your role as you work to develop new models and simulations of biological systems.
Microbiologist
Microbiologists study microorganisms, such as bacteria, viruses, and fungi. The course will help you develop a foundation in bioinformatics and data analysis, which are essential skills for microbiologists. The knowledge and skills gained in the course will be directly applicable to your role as you work to identify and characterize microorganisms, and develop new treatments for infectious diseases.
Biostatistician
Biostatisticians use statistical methods to solve problems in biology and medicine. The course will help you develop a strong foundation in statistics and bioinformatics, which are essential skills for biostatisticians. The knowledge and skills gained in the course will be directly applicable to your role as you work with scientists and researchers to design and analyze studies.
Data Analyst
Data Analysts use their knowledge of statistics and programming to analyze data for a variety of purposes. The course will help build a foundation in Python, data analysis methods, and bioinformatics, which are all essential skills for data analysts. The knowledge gained in the course can help you succeed in this role, particularly if you are interested in working with healthcare data.
Epidemiologist
Epidemiologists study the causes and patterns of disease in populations. The course will provide you with a foundation in bioinformatics and data analysis, which are essential skills for epidemiologists. These skills will be directly applicable to your role as you work to investigate outbreaks, identify risk factors for disease, and develop prevention and control strategies.
Research Scientist
Research scientists conduct research in a variety of fields, including biology, chemistry, and physics. The course will provide you with a foundation in bioinformatics, data analysis, and programming, which are essential skills for research scientists. The knowledge and skills gained in the course will be directly applicable to your role as you work to design and conduct research studies.
Public Health Consultant
Public health consultants provide advice to public health organizations on a variety of topics, including program planning, evaluation, and policy development. The course will help you develop your skills in data analysis and problem-solving, which are essential for public health consultants. The knowledge and skills gained in the course will be directly applicable to your role as you work to help public health organizations improve the health of their communities.
Healthcare Consultant
Healthcare consultants provide advice to healthcare organizations on a variety of topics, including strategy, operations, and finance. The course will help you develop your skills in data analysis and problem-solving, which are essential for healthcare consultants. The knowledge and skills gained in the course will be directly applicable to your role as you work to help healthcare organizations improve their performance.
Clinical Research Associate
As a Clinical Research Associate, you will need to be knowledgeable in the science behind diseases, new and emerging treatments, and how clinical trials are run. The course will help build a foundation in bioinformatics and provide a deeper understanding of how viruses work. This knowledge will be applicable in your role as you work with clinical investigators to design and conduct clinical trials.
Science Educator
Science educators teach science to students of all ages. The course will help you develop your skills in teaching and communicating about science, which are essential for science educators. The knowledge and skills gained in the course will be directly applicable to your role as you work to develop and deliver science lessons.
Science Writer
Science writers communicate complex scientific information to a variety of audiences. The course will help you develop your skills in writing and communicating about science, which are essential for science writers. The knowledge and skills gained in the course will be directly applicable to your role as you work to write articles, blog posts, and other materials about science.
Medical Writer
Medical writers create written materials about medical topics for a variety of audiences, including patients, doctors, and researchers. The course will help you develop your skills in writing and communicating about science, which are essential for medical writers. The knowledge and skills gained in the course will be directly applicable to your role as you work to write articles, blog posts, and other materials about medical topics.
Patent Attorney
Patent attorneys help clients obtain and protect patents for their inventions. The course will help you develop your understanding of the patent process and the legal principles that govern patents. The knowledge and skills gained in the course will be directly applicable to your role as you work to help clients protect their intellectual property.

Reading list

We've selected nine books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in تحليل المجموعات الهرمية باستخدام المسافات الإقليدية.
Provides a comprehensive overview of algorithms for bioinformatics, including sequence alignment, phylogenetic analysis, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of bioinformatics and phylogenetics, including sequence analysis, phylogenetic analysis, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of bioinformatics and functional genomics, including sequence analysis, protein structure prediction, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of computational molecular biology, including sequence analysis, protein structure prediction, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of statistical methods in bioinformatics, including sequence analysis, phylogenetic analysis, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of machine learning in bioinformatics, including sequence analysis, protein structure prediction, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of bioinformatics, including sequence analysis, protein structure prediction, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of bioinformatics, including sequence analysis, protein structure prediction, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.
Provides a comprehensive overview of bioinformatics, including sequence analysis, protein structure prediction, and gene expression analysis. It would be a valuable reference for students and researchers in the field of bioinformatics.

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