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Anne M. Libby, PhD

This course is targeted to early career and novice researchers writing their first major competitive biomedical / health research grant proposals. After the course, you will be able to:

1) Identify and summarize key decisions in study design that align scope and complexity with budget and timeline;

2) Describe key variables and their relationships to each other; and

3) Interpret essential parts of a power analysis and summarize appropriate questions for an expert biostatistician.

Read more

This course is targeted to early career and novice researchers writing their first major competitive biomedical / health research grant proposals. After the course, you will be able to:

1) Identify and summarize key decisions in study design that align scope and complexity with budget and timeline;

2) Describe key variables and their relationships to each other; and

3) Interpret essential parts of a power analysis and summarize appropriate questions for an expert biostatistician.

We are faculty at a major research institution with proven experience training others to health sciences research career success. Study design and analysis planning are key skills for grant writing. This course is part of a larger Specialization called Grant Writing for Health Researchers. Please consider taking the other two courses on (1) Grant proposal plans, sections, and resubmission, and (2) Scientific writing. Together, these have been a recipe for success for researchers at the University of Colorado and beyond. Upon completion, you will earn an e-badge to display your new skills. Please join us!

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What's inside

Syllabus

Study Design & Scope
Learn how your choices on study design affect project scope, especially data collection, intervention type, and timeline.
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Traffic lights

Read about what's good
what should give you pause
and possible dealbreakers
Describes factors key to developing and planning a project
Emphasizes the need for a solid foundation in study design and analysis for grant writing success
Coursework is part of a specialization, offering a comprehensive approach to grant writing
Designed for novice researchers writing their first major grant proposals
Led by faculty with expertise in health sciences research

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Reviews summary

Biostatistics essentials for grant writing

According to learners, this course offers a practical and highly relevant guide to biostatistics for health research grant writing. Students consistently praise its ability to demystify complex topics like power analysis and study design, making them accessible even for novice researchers. The lectures are clear, and the focus on engaging statistical support is particularly valuable. While some express a desire for more hands-on calculation examples, the course excels at preparing you to effectively frame research questions and understand statistical needs for successful grant proposals, especially as part of its specialization.
Course is a valuable part of a larger grant writing specialization.
"Highly recommend it as part of the specialization."
"I'm taking the other courses in the specialization next."
"This course fills a critical gap within the broader context of grant writing education."
Provides invaluable advice on working with biostatisticians.
"The section on engaging statistical support was invaluable, providing practical advice I hadn't found elsewhere."
"The information on power analysis and knowing when to consult experts is crucial."
"It prepares me well for talking to biostatisticians."
"I learned strategies to find biostatistical mentoring."
Simplifies biostatistical concepts for non-statisticians.
"The instructor broke down complex topics like power analysis and sample size calculation into digestible modules."
"Excellent course! It demystifies the statistical component of grant writing."
"It clearly explains how to conceptualize study design and variables in a grant context."
"I found it prepared me well for talking to biostatisticians without getting bogged down in jargon."
Highly relevant for grant writing and researcher communication.
"This course was incredibly helpful for navigating the biostatistical aspects of my grant proposal."
"A solid introduction to biostatistics in the context of grant writing."
"It truly helps to align my research scope with statistical feasibility."
"I learned to use practical tools and strategies that I could apply immediately to my work in grant proposal writing."
Some learners wished for more hands-on calculation practice.
"I expected more hands-on examples for actual power calculations. It feels more conceptual than practical in some areas."
"I found it a bit too high-level... More examples or practical exercises would have been beneficial."
"While it's great for understanding the *why* of biostatistics in grants, I struggled with the *how*."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Biostatistics Study Design and Analysis for Grant Writing with these activities:
Read 'Statistical Methods for Psychology' by Dale Lehman.
This course builds upon several of the concepts from the primary text in this course. Completing this book before the class will provide a solid foundation for the course.
Show steps
  • Read Chapter 1: Introduction to Statistics.
  • Read Chapter 2: Linear Regression.
Review linear regression.
This course relies on learners already knowing how to compute a linear regression model and interpret the results. Review those concepts before beginning the course to enhance success.
Browse courses on Linear Regression
Show steps
  • Review the linear regression formula and key assumptions.
  • Identify use cases where linear regression is the appropriate modeling strategy.
  • Practice fitting and evaluating a linear regression model using a programming language you are comfortable with.
Complete the Coursera tutorial on ANOVA.
ANOVA is a key topic covered in this course. Following along with this tutorial will provide an introductory overview of the topic.
Show steps
  • Follow the Coursera tutorial on ANOVA.
  • Complete the practice exercises provided in the tutorial.
Six other activities
Expand to see all activities and additional details
Show all nine activities
Solve 20 practice problems on hypothesis testing.
Hypothesis testing plays a key role in statistical research. Solving a series of practice problems will help to solidify the key concepts.
Show steps
  • Find a set of 20 practice problems on hypothesis testing.
  • Solve the problems, showing all of your work.
  • Check your answers against the provided solutions.
Write a blog post explaining logistic regression.
Logistic regression will be covered in this course. Creating a blog post will help master the material by organizing and summarizing it to then be able to clearly explain it.
Show steps
  • Explain the concept of logistic regression.
  • Provide examples of how logistic regression is used in practice.
  • Walk through a simple logistic regression example using a programming language or statistical software.
Attend a workshop on statistical power analysis.
Statistical power analysis is an important topic covered in this course. Attending a workshop will provide an in-depth understanding of the topic.
Show steps
  • Identify a workshop on statistical power analysis that fits your schedule and interests.
  • Register for the workshop.
  • Attend the workshop and actively participate in the activities.
Join a study group and meet weekly to discuss the course material.
Collaborative learning can greatly improve learning outcomes. This activity provides learners with an opportunity to work with peers to solidify their knowledge and understanding.
Show steps
  • Identify 2-3 other learners who are interested in forming a study group.
  • Meet weekly to discuss the course material.
  • Review the lecture notes and assigned readings before each meeting.
  • Take turns leading the discussion and presenting your understanding of the material.
Create a collection of resources on statistical methods.
This course covers a wide range of statistical methods. Creating a collection of resources will help to organize and summarize the materials for easier reference.
Show steps
  • Identify and gather resources on statistical methods, such as articles, tutorials, and videos.
  • Organize the resources into a coherent structure.
  • Share the collection with other learners.
Conduct a small-scale statistical analysis project.
This course aims to prepare students to conduct statistical analysis. Completing a small-scale project is a great way to apply the knowledge and skills gained from the course.
Show steps
  • Identify a research question that you are interested in exploring.
  • Collect data relevant to your research question.
  • Analyze the data using statistical methods.
  • Write a report summarizing your findings.

Career center

Learners who complete Biostatistics Study Design and Analysis for Grant Writing will develop knowledge and skills that may be useful to these careers:

Reading list

We've selected 50 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Biostatistics Study Design and Analysis for Grant Writing.
The third edition of the essential guide to data wrangling with pandas, NumPy, and Jupyter in Python. Updated for newer versions of the libraries, this book remains a core resource for anyone performing data analysis in Python. It widely used textbook and reference for its clear explanations and practical examples.
Considered a foundational text in modern epidemiology, this book provides an in-depth treatment of epidemiological principles and methods. It is essential for those seeking to deepen their understanding of this core health research discipline. It classic and widely referenced book in the field.
Addressing the crucial ethical considerations in health research, this book delves into the principles, practice, and policies governing ethical conduct. It is essential reading for all levels of researchers to ensure responsible research practices. It provides a framework for analyzing ethical aspects of studies.
Provides a foundational understanding of the fundamental principles of data science and the data-analytic thinking necessary for extracting value from data in a business context. It is highly relevant for undergraduate business analytics programs and working professionals. It serves as a useful reference for understanding the business applications of data analysis and is commonly used as a textbook.
This comprehensive guide provides a step-by-step approach to study design and statistical analysis, covering topics such as hypothesis testing, sample size determination, and data analysis techniques. It valuable resource for clinicians and researchers who need to design and analyze clinical studies.
This classic textbook provides a comprehensive overview of clinical research design, with a focus on epidemiologic methods. It covers topics such as study design, data collection, analysis, and interpretation. It valuable resource for clinicians and researchers who want to design and conduct clinical studies.
Provides a comprehensive overview of sampling methods used in survey research. It covers both probability and non-probability sampling methods, and discusses the strengths and weaknesses of each method.
Classic in the field of Bayesian statistics and provides a detailed treatment of the concept of power. This book valuable resource for researchers who want to learn more about the theoretical foundations of power analysis.
Classic in the field of power analysis and provides a detailed treatment of the topic. This book valuable resource for researchers who want to learn more about the theoretical foundations of power analysis.
This integrated text covers the key areas of epidemiology, biostatistics, and preventive medicine, providing a strong foundation for understanding public health research. It is often used as a textbook and is valuable for students and practitioners in public health and related fields.
Delivering an exploration of statistics in applied health science and biostatistics, this book focuses on the correct use and interpretation of statistics. It covers various statistical concepts and methods relevant to health research. It is suitable for upper undergraduate and graduate levels and serves as a reference for practitioners.
Focuses on the crucial skill of communicating insights from data effectively through compelling visualizations. is highly relevant for all levels, emphasizing the importance of clear and impactful data presentation. It is valuable additional reading that complements technical data analysis skills.
Bridges the gap between statistical theory and its practical application in data science using R and Python. It focuses on the statistical concepts most relevant to data scientists and provides code examples. It's a useful reference and learning resource for those applying statistics in their work.
Provides a comprehensive introduction to biostatistics as used in the health sciences. It covers fundamental concepts and techniques, essential for understanding the quantitative aspects of health research. It is suitable for both undergraduate and graduate students and can serve as a professional reference.
Offers a practical introduction to epidemiology, biostatistics, and research methodology with an emphasis on quantitative methods. It covers a range of contemporary methods and helps develop critical skills for data analysis and interpretation. It's suitable for health professionals and students.
Offers a new way of thinking about data science and ethics informed by intersectional feminist thought. It challenges existing power structures within data and explores how data can be used to work towards justice. It's highly relevant for contemporary discussions around fairness and bias in data analysis.
This textbook provides a comprehensive overview of power analysis, with a particular focus on applications in the social and behavioral sciences. It covers topics such as effect size estimation, hypothesis testing, and sample size determination. valuable resource for researchers who need to understand and apply power analysis in their work.
Focuses on the application of statistical methods to medical research. It covers topics such as clinical trials, epidemiology, and public health. It is an excellent resource for researchers who need to design and analyze medical studies.
Core text for understanding and practicing evidence-based medicine, a critical approach in contemporary health research. It provides guidance on incorporating the best evidence into clinical decision-making. It widely recognized resource in the field.
Introduces core qualitative methods for data collection and analysis in healthcare research. The latest edition includes newer methods and explores the role of theory and digital data. It's a valuable resource for understanding qualitative approaches in depth and is used in academic courses.
Focuses on applying epidemiological principles to clinical practice research. It's valuable for researchers and clinicians interested in conducting studies in healthcare settings. It well-regarded resource in evidence-based medicine and clinical research.
Aims to make epidemiology accessible, covering both classic and modern concepts. It's a good resource for gaining a broad understanding of epidemiological principles without getting bogged down in complex details. It's suitable for beginners and provides a solid introduction.
Comprehensive overview of power analysis and effect size analysis for research. It provides detailed instructions on how to conduct power analyses and interpret the results. This book valuable resource for researchers who need to apply power analysis in their work.
Provides a guide to creating effective and aesthetically pleasing data visualizations. It delves into the principles behind good visualization design, helping readers make informed choices about how to represent their data. It valuable reference for anyone creating visualizations, from students to professionals.
Is an excellent starting point for anyone new to data analysis or statistics. It demystifies core statistical concepts without relying heavily on mathematical formulas, making it highly accessible for high school and undergraduate students. It provides a strong foundation in the intuition behind statistical analysis and helps readers understand how data can be used and misused. This is valuable background reading that builds prerequisite knowledge.
Teaches probability and statistics using a computational approach with Python. It's ideal for students and professionals with programming experience who want to understand statistical concepts by doing. It helps solidify understanding through hands-on application.
Focused on the practical skill of writing grant proposals for health research, this book is highly relevant for those seeking funding. It provides a step-by-step guide and tips for crafting competitive proposals. This is particularly useful for graduate students and working professionals.
Provides a comprehensive overview of cohort studies, including chapters on study design, data collection, analysis, and interpretation. It valuable resource for researchers who want to design and conduct cohort studies.
This practical guide provides step-by-step instructions for writing successful grant proposals, including tips and templates.
Covers the fundamentals of biostatistics, including descriptive statistics, probability, inferential statistics, and regression analysis. It is written in a clear and concise style, making it an excellent choice for students and researchers who are new to the field.
Provides a comprehensive overview of causal inference in statistics. It covers topics such as graphical models, counterfactuals, and causal effects. It valuable resource for researchers who want to learn about causal inference methods.
A timeless classic that remains highly relevant today. exposes common ways statistics can be manipulated or misinterpreted, fostering a critical eye essential for anyone working with data. It's valuable for all levels, from high school to professional, as it highlights the importance of data integrity and ethical considerations. This serves as crucial additional reading to develop data literacy.
Provides a comprehensive overview of epidemiology, covering topics such as study design, data collection, data analysis, and interpretation of results. It is an excellent resource for students and researchers who need a strong foundation in epidemiology.
SQL fundamental skill for data analysis, and this book delves into advanced techniques for working with data in databases. It's essential for anyone who needs to retrieve and manipulate data stored in relational databases. It serves as a valuable reference for more complex data extraction and transformation tasks.
Explores the world of prediction and forecasting across various fields, demonstrating how data analysis and statistical modeling are used in practice. It's particularly engaging for undergraduate and graduate students interested in the application of data analysis in real-world scenarios. It adds breadth by showcasing diverse applications and the challenges involved in making accurate predictions.
Provides a high-level overview of the data science process, from asking questions to interpreting results. It focuses on the principles and concepts rather than specific tools, making it suitable for a broad audience. It helps in gaining a broad understanding of the data analysis workflow.
This workbook provides exercises and activities to help grant writers develop their skills and improve their proposals.
Provides a comprehensive overview of mixed methods research, with a focus on planning and conducting mixed methods studies. It covers topics such as research design, data collection, analysis, and interpretation. It valuable resource for researchers who want to design and conduct mixed methods studies.
Provides tables for determining the appropriate sample size for clinical studies. It covers a wide range of study designs and statistical tests, making it a useful resource for researchers in clinical research.
A pragmatic guide focusing on qualitative research methods in health, this book is valuable for those seeking to understand this specific approach. It covers the research process for qualitative studies, from design to analysis and reporting. is more valuable as additional reading for those interested in qualitative methods.
This undergraduate-level textbook introduces the principles and techniques of grant writing, providing a foundation for further study.
While more focused on the engineering aspects of data systems, this book provides a deep understanding of the underlying infrastructure for data analysis. It's particularly valuable for graduate students and professionals involved in building and maintaining data pipelines and databases. It adds significant depth to understanding the data landscape.
A seminal work on information design and data visualization. While not specific to data analysis techniques, its principles are fundamental for effectively presenting data. It's a classic that influences how we think about visual communication of quantitative information.

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