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Biostatistics Study Design and Analysis for Grant Writing

Anne M. Libby, PhD

This course is targeted to early career and novice researchers writing their first major competitive biomedical / health research grant proposals. After the course, you will be able to:

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This course is targeted to early career and novice researchers writing their first major competitive biomedical / health research grant proposals. After the course, you will be able to:

1) Identify and summarize key decisions in study design that align scope and complexity with budget and timeline;

2) Describe key variables and their relationships to each other; and

3) Interpret essential parts of a power analysis and summarize appropriate questions for an expert biostatistician.

We are faculty at a major research institution with proven experience training others to health sciences research career success. Study design and analysis planning are key skills for grant writing. This course is part of a larger Specialization called Grant Writing for Health Researchers. Please consider taking the other two courses on (1) Grant proposal plans, sections, and resubmission, and (2) Scientific writing. Together, these have been a recipe for success for researchers at the University of Colorado and beyond. Upon completion, you will earn an e-badge to display your new skills. Please join us!

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What's inside

Syllabus

Study Design & Scope
Learn how your choices on study design affect project scope, especially data collection, intervention type, and timeline.
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Study Variables
Learn to characterize key variables by the roles they play in your research questions.
Data Analysis Plan
Learn how to prepare the component parts of an analysis plan.
Power Analysis & Sample Size
Learn key parts of power analyses in grant proposals and how to isolate unknown values.
Engaging Statistical Support, Training, & Mentoring
Learn differences in statistical support and strategies to find biostatistical mentoring.

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Describes factors key to developing and planning a project
Emphasizes the need for a solid foundation in study design and analysis for grant writing success
Coursework is part of a specialization, offering a comprehensive approach to grant writing
Designed for novice researchers writing their first major grant proposals
Led by faculty with expertise in health sciences research

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Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Biostatistics Study Design and Analysis for Grant Writing with these activities:
Read 'Statistical Methods for Psychology' by Dale Lehman.
This course builds upon several of the concepts from the primary text in this course. Completing this book before the class will provide a solid foundation for the course.
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  • Read Chapter 1: Introduction to Statistics.
  • Read Chapter 2: Linear Regression.
Review linear regression.
This course relies on learners already knowing how to compute a linear regression model and interpret the results. Review those concepts before beginning the course to enhance success.
Browse courses on Linear Regression
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  • Review the linear regression formula and key assumptions.
  • Identify use cases where linear regression is the appropriate modeling strategy.
  • Practice fitting and evaluating a linear regression model using a programming language you are comfortable with.
Complete the Coursera tutorial on ANOVA.
ANOVA is a key topic covered in this course. Following along with this tutorial will provide an introductory overview of the topic.
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  • Follow the Coursera tutorial on ANOVA.
  • Complete the practice exercises provided in the tutorial.
Six other activities
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Solve 20 practice problems on hypothesis testing.
Hypothesis testing plays a key role in statistical research. Solving a series of practice problems will help to solidify the key concepts.
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  • Find a set of 20 practice problems on hypothesis testing.
  • Solve the problems, showing all of your work.
  • Check your answers against the provided solutions.
Write a blog post explaining logistic regression.
Logistic regression will be covered in this course. Creating a blog post will help master the material by organizing and summarizing it to then be able to clearly explain it.
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  • Explain the concept of logistic regression.
  • Provide examples of how logistic regression is used in practice.
  • Walk through a simple logistic regression example using a programming language or statistical software.
Attend a workshop on statistical power analysis.
Statistical power analysis is an important topic covered in this course. Attending a workshop will provide an in-depth understanding of the topic.
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  • Identify a workshop on statistical power analysis that fits your schedule and interests.
  • Register for the workshop.
  • Attend the workshop and actively participate in the activities.
Join a study group and meet weekly to discuss the course material.
Collaborative learning can greatly improve learning outcomes. This activity provides learners with an opportunity to work with peers to solidify their knowledge and understanding.
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  • Identify 2-3 other learners who are interested in forming a study group.
  • Meet weekly to discuss the course material.
  • Review the lecture notes and assigned readings before each meeting.
  • Take turns leading the discussion and presenting your understanding of the material.
Create a collection of resources on statistical methods.
This course covers a wide range of statistical methods. Creating a collection of resources will help to organize and summarize the materials for easier reference.
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  • Identify and gather resources on statistical methods, such as articles, tutorials, and videos.
  • Organize the resources into a coherent structure.
  • Share the collection with other learners.
Conduct a small-scale statistical analysis project.
This course aims to prepare students to conduct statistical analysis. Completing a small-scale project is a great way to apply the knowledge and skills gained from the course.
Show steps
  • Identify a research question that you are interested in exploring.
  • Collect data relevant to your research question.
  • Analyze the data using statistical methods.
  • Write a report summarizing your findings.

Career center

Learners who complete Biostatistics Study Design and Analysis for Grant Writing will develop knowledge and skills that may be useful to these careers:

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