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Jeff Gore, Paul Blainey, Eric S. Lander, Ernest Fraenkel, Mary Ellen Wiltrout, and Nathaniel Schafheimer

Do you have an interest in biology and quantitative tools? Do you know computational methods but do not realize how they apply to biological problems? Do you know biology but do not understand how scientists really analyze complicated data? 7.QBWx: Quantitative Biology Workshop is designed to give learners exposure to the application of quantitative tools to analyze biological data at an introductory level. The Biology Department of MIT has run this workshop-style course as part of a one-week outreach program for students from other universities. With 7.QBWx, we can give more learners from around the world the chance to discover quantitative biology. We hope that this series of workshops encourages learners to explore new interests and take more biology and computational courses.

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Do you have an interest in biology and quantitative tools? Do you know computational methods but do not realize how they apply to biological problems? Do you know biology but do not understand how scientists really analyze complicated data? 7.QBWx: Quantitative Biology Workshop is designed to give learners exposure to the application of quantitative tools to analyze biological data at an introductory level. The Biology Department of MIT has run this workshop-style course as part of a one-week outreach program for students from other universities. With 7.QBWx, we can give more learners from around the world the chance to discover quantitative biology. We hope that this series of workshops encourages learners to explore new interests and take more biology and computational courses.

We expect that learners from 7.00x Introduction to Biology - The Secret of Life or an equivalent course can complete this workshop-based course without a background in programming. The course content will introduce programming languages but will not teach any one language in a comprehensive manner. The content of each week varies. We want learners to have an introduction to multiple languages and tools to find a topic that they would want to explore more. We recommend that learners try to complete each week to find what interests them the most.

This workshop includes activities on the following biological topics: population biology, biochemical equilibrium and kinetics, molecular modeling of enzymes, visual neuroscience, global and single-cell gene expression, development, and genomics. The tools and programming languages include MATLAB, PyMOL, Python, and R. This course does not require learners to download MATLAB. All MATLAB activities run and are graded within the edX platform. We do recommend that participants download a few other free tools for the activities so that they learn how to use the same tools and programs that scientists use.

Workshop Content Creators and Residential Leaders

Gregory Hale, Michael Goard, Ben Stinson, Kunle Demuren, Sara Gosline, Glenna Foight, Leyla Isik, Samir El-Boustani, Gerald Pho, and Rajeev Rikhye

Residential Outreach Workshop Organizer and Creator

Mandana Sassanfar

What's inside

Learning objectives

  • Apply quantitative methods to biological problems
  • Define computational vocabulary
  • Write python, matlab, and r code to analyze biological data
  • Examine any protein structure in pymol
  • Analyze how to answer a scientific question through a step-by-step thought process.

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Designed for those with biological interests who use quantitative tools in biology or vice-versa
Develops expertise in the use of tools and methods like MATLAB, PyMOL, Python, and R
Conducive for beginners with introductory level biology and no programming background
Covers a wide range of biological topics like population biology, global gene expression and genomics
Emphasizes problem-solving and critical thinking by introducing a step-by-step approach to answering scientific questions
Taught by a team of renowned instructors with expertise in biology, quantitative methods, and research

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Reviews summary

Excellent quantitative biology

According to students, this course titled "Quantitative Biology" is excellent! Students say it's challenging, covers lots of important topics, has great learning content, materials, and lectures, and features difficult but well-explained content and even exposure to tutorials from MathWorks. Overall, students say this course is a great value.
This course provides great learning materials, content, and lectures.
"Great lectures and terrific course materials."
This course covers a wide range of important and interesting topics in quantitative biology.
"Covers a very wide range of extremely interesting and important topics in quantitative biology."
The concepts covered may be difficult, but the explanations provided are clear.
"I found the learning content in this course challenging..."
"The way they explain is really good even if you don't know anything of programming or biology"

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Quantitative Biology Workshop with these activities:
Explore MATLAB Tutorials
Strengthen your foundational understanding of MATLAB to enhance your ability to apply it to biological problems.
Browse courses on MATLAB
Show steps
  • Find online tutorials for MATLAB basics
  • Complete the tutorials to gain proficiency in MATLAB syntax and commands
Revisit basic algebra and statistics
This will ensure you are ready to jump into the more challenging aspects of the course
Show steps
  • Review your notes from high school algebra
  • Take a practice statistics quiz online
Brush up on your programming skills
Brushing up on your programming skills will help you to succeed in the course, which requires you to be able to write code to analyze biological data.
Browse courses on Programming
Show steps
  • Take a programming course or tutorial.
  • Work on programming projects.
  • Contribute to open source projects.
12 other activities
Expand to see all activities and additional details
Show all 15 activities
Practice using a programming language
You will need to be able to write code to complete the assignments in this course
Browse courses on Python
Show steps
  • Complete a coding tutorial in the language of your choice
  • Solve a few coding challenges online
Follow a series of online tutorials on quantitative biology
Following online tutorials can help you to learn the basics of quantitative biology and to get started with using programming tools.
Show steps
  • Find a series of online tutorials that cover the topics you are interested in.
  • Set aside regular time to watch the tutorials.
  • Take notes on the material.
  • Complete the exercises and assignments.
Form a study group with other students in the course
Studying with other students can help you to learn the material and to prepare for exams.
Show steps
  • Find other students in the course who are interested in forming a study group.
  • Set up a regular meeting time.
  • Discuss the course material.
  • Work on problem sets together.
  • Quiz each other on the material.
Join a study group with other students in the course
This will provide you with a support network and allow you to learn from others
Show steps
  • Find a study group that meets your schedule and learning style
  • Attend study group meetings regularly
  • Participate in discussions and ask questions
Practice coding problems in Python, MATLAB, and R
Working through coding problems will help to improve your programming skills and your ability to solve biological problems with computational approaches.
Show steps
  • Find a set of coding problems that cover the topics you are learning in the course.
  • Set aside regular time to work on the problems.
  • Don't give up if you get stuck. Seek help from the course forums or from a tutor.
  • Keep a notebook to track your progress and the solutions to the problems you have solved.
Quantitative Biology Practice Exercises
Reinforce your understanding of quantitative biology concepts by solving practical exercises.
Show steps
  • Identify online platforms or textbooks with quantitative biology exercises
  • Solve the exercises, focusing on applying the concepts to real-world biological problems
Follow tutorials on using PyMOL
PyMOL is a powerful tool for visualizing and analyzing molecular structures
Browse courses on PyMOL
Show steps
  • Watch a tutorial on the basics of PyMOL
  • Complete a few practice exercises in PyMOL
Create a collection of resources on quantitative biology
Creating a collection of resources can help you to learn about the field and to find the information you need.
Show steps
  • Start by brainstorming a list of topics that you are interested in.
  • Use a search engine to find resources on those topics.
  • Organize the resources into a collection.
  • Share the collection with others.
Complete practice problems on population biology
Population biology is a fundamental concept in biology
Show steps
  • Solve practice problems on population growth and decline
  • Analyze data on population dynamics
Build a computational model of a biological system
Building a computational model will help you to understand the behavior of the system and to make predictions about its behavior under different conditions.
Show steps
  • Choose a biological system that you are interested in.
  • Identify the key components of the system and the interactions between them.
  • Develop a mathematical model of the system.
  • Implement the model in a programming language.
  • Test the model and make sure that it accurately reproduces the behavior of the system.
Write a blog post on a topic related to quantitative biology
This will help you to solidify your understanding of the material and to communicate your knowledge to others
Show steps
  • Choose a topic that you are interested in
  • Research the topic and gather information
  • Write a blog post that explains the topic clearly and concisely
Create a tutorial on a quantitative biology topic
Creating a tutorial will help you to solidify your understanding of the topic and to share your knowledge with others.
Show steps
  • Choose a topic that you are comfortable with.
  • Develop a plan for your tutorial.
  • Create the content for your tutorial.
  • Share your tutorial with others.

Career center

Learners who complete Quantitative Biology Workshop will develop knowledge and skills that may be useful to these careers:
Computational Biologist
Computational Biologists use computer science and numerical analysis to address problems in biology, often in collaboration with biologists who study those problems from a more qualitative point of view. In a career as a Computational Biologist, you can expect to use your expertise in two distinct areas: mathematics, computer science, and life sciences. This course provides an opportunity to build foundational knowledge in computational approaches and apply them in the context of biological problems, preparing you for success in this field.
Biostatistician
Biostatisticians apply statistical methods to biological data, helping to design experiments, analyze data, and interpret results. In your career as a Biostatistician, you can expect to use statistical models to analyze data and draw conclusions about biological processes. This course will help you build foundational knowledge in data analysis and programming, preparing you for success in this field.
Data Scientist
Data Scientists use scientific methods, processes, algorithms, and systems to extract knowledge and insights from data. This course will help you build a foundation in data analysis and visualization, preparing you for success in this field.
Biomedical Engineer
Biomedical Engineers apply engineering principles to solve problems in medicine and biology. In this career field, you can expect to design and develop medical devices and treatments. This course provides an opportunity to apply computational methods to biological problems, which is a valuable skill for Biomedical Engineers.
Software Engineer
Software Engineers design, develop, and maintain software applications. This course will help you build a foundation in programming and software development, preparing you for success in this field.
Quantitative Analyst
Quantitative Analysts use mathematical and statistical methods to analyze data and make predictions. In a career as a Quantitative Analyst, you can expect to use your expertise in math and programming to develop models and make predictions in areas such as finance and economics. This course provides an opportunity to build a foundation in programming and data analysis, which will be beneficial for a Quantitative Analyst.
Computational Geneticist
Computational Geneticists use computer science and mathematics to study the human genome. This course will help you build a foundation in programming and data analysis, which will be beneficial for a Computational Geneticist.
Bioinformatician
Bioinformaticians use computer science and mathematics to analyze biological data. This course will help you build a foundation in programming and data analysis, which is beneficial for a Bioinformatician.
Neuroscientist
Neuroscientists study the nervous system. In this career field, you can expect to study the structure and function of the brain and spinal cord. This course provides an opportunity to apply computational methods to the study of the nervous system, which is an emerging field of research.
Epidemiologist
Epidemiologists study the distribution and determinants of health-related states or events (including disease), and the application of this study to the control of diseases and other health problems. This course provides an introduction to data analysis and programming, which can be applied to the study of epidemiology.
Systems Biologist
Systems Biologists use mathematical and computational methods to model and analyze complex biological systems. In this career, you can expect to use your expertise in math and programming to develop models of biological systems and make predictions about their behavior. This course provides an introduction to computational methods for analyzing biological data, which is a valuable skill for Systems Biologists.
Science Writer
Science Writers communicate complex scientific information to a general audience. In this career, you can expect to write articles, blog posts, and other forms of content that explain scientific concepts in a clear and engaging way. This course will help you build your science communication skills by providing you with an opportunity to write about your own research findings.
Healthcare Data Analyst
Healthcare Data Analysts use data analysis techniques to improve the quality and efficiency of healthcare delivery. This course will help you build foundational knowledge in data analysis and programming, preparing you for success in this field.
Medical Physicist
Medical Physicists use their knowledge of physics to solve problems in medicine. This course provides an opportunity to apply computational methods to medical problems, which is a valuable skill for Medical Physicists.
Biomedical Imaging Scientist
Biomedical Imaging Scientists use medical imaging techniques to diagnose and treat diseases. This course will help you build foundational knowledge in programming and data analysis, preparing you for success in this field.

Reading list

We've selected 29 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Quantitative Biology Workshop.
An in-depth exploration of quantitative biology, this book broadly covers techniques used in the field and includes extensive case studies.
This textbook provides a comprehensive overview of bioinformatics, covering topics ranging from sequence analysis to gene expression analysis. It valuable resource for students and researchers interested in learning about the field of bioinformatics.
This textbook provides a comprehensive overview of sequence and genome analysis, covering topics ranging from sequence alignment to gene prediction. It valuable resource for students and researchers interested in learning about the field of bioinformatics.
Provides a comprehensive overview of computational biology, covering topics such as DNA sequencing, genome assembly, and protein structure prediction. It good resource for those who want to learn more about the foundations of computational biology.
Provides an algorithmic approach to computational molecular biology, covering topics such as sequence alignment, gene finding, and genome assembly. It good resource for those who want to learn more about the algorithmic techniques used in computational biology.
Provides a comprehensive overview of machine learning methods used in bioinformatics, covering topics such as supervised learning, unsupervised learning, and feature selection. It good resource for those who want to learn more about the machine learning methods used in computational biology.
Provides a comprehensive overview of bioinformatics and functional genomics, covering topics such as gene expression analysis, genome-wide association studies, and comparative genomics. It good resource for those who want to learn more about the bioinformatics methods used in genomics.
Provides a practical guide to programming in Python for bioinformatics, covering topics such as data structures, algorithms, and web scraping. It good resource for those who want to learn more about the programming skills used in computational biology.
Provides a comprehensive overview of bioinformatics, covering topics such as sequence analysis, gene expression analysis, and protein structure prediction. It good resource for those who want to learn more about the foundational concepts of bioinformatics.
This textbook provides a practical guide to statistical methods in bioinformatics. It valuable resource for students and researchers interested in learning how to use statistical methods to analyze biological data.
Provides a comprehensive introduction to the Python programming language. It good resource for students who want to learn how to use Python to analyze biological data.
Provides a comprehensive introduction to the R programming language. It good resource for students who want to learn how to use R to analyze biological data.
Provides a comprehensive overview of biochemical equilibrium and kinetics. It good resource for students who want to learn more about the mathematical and computational tools used to study biochemical reactions.
Provides a comprehensive overview of molecular modeling of enzymes. It good resource for students who want to learn more about the mathematical and computational tools used to study enzyme structure and function.
Provides a comprehensive overview of statistical learning. It good resource for students who want to learn more about the mathematical and computational tools used to analyze biological data.
Provides a comprehensive overview of Bayesian data analysis. It good resource for students who want to learn more about the mathematical and computational tools used to analyze biological data.
This textbook provides a concise overview of bioinformatics, covering topics ranging from sequence analysis to gene expression analysis. It valuable resource for students and researchers interested in learning the basics of bioinformatics.
Provides a good overview of the mathematical and computational tools used in quantitative biology. It comprehensive textbook that covers a wide range of topics, from population biology to gene expression.
Provides a comprehensive overview of data mining, including topics such as data preprocessing, feature selection, and model evaluation. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
Comprehensive guide to machine learning in Python, including topics such as supervised learning, unsupervised learning, and reinforcement learning. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
Comprehensive overview of deep learning, including topics such as convolutional neural networks, recurrent neural networks, and generative adversarial networks. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
Comprehensive overview of machine learning, including topics such as supervised learning, unsupervised learning, and reinforcement learning. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
Provides a comprehensive introduction to probabilistic graphical models, including topics such as Bayesian networks, Markov random fields, and conditional random fields. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
Provides a comprehensive overview of machine learning from a probabilistic perspective, including topics such as supervised learning, unsupervised learning, and reinforcement learning. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
Provides a comprehensive overview of deep learning, including topics such as convolutional neural networks, recurrent neural networks, and generative adversarial networks. It valuable resource for students and researchers interested in machine learning and artificial intelligence.
This textbook provides a gentle introduction to bioinformatics, covering topics ranging from sequence analysis to gene expression analysis. It valuable resource for students and researchers interested in learning about the field of bioinformatics.

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