Stereochemistry III : Conformational Isomerism in 3D. from Udemy

This course is unique in itself. The instructor has used his total knowledge, teaching skills, teaching experience , animation and technology to make the couse live. This course is sellf explanatory. Anyone with a basic knowlege of chemistry can go through the couse and master in the conformational Isomerism.

Generous use of 3D animation to illustrate the concepts of 1. Newman & Fisher Projection, 2. Vanderwall and Torsional Strain, 3. Intramolecular Hbond in Gauche form, 4. Conformation of butane and brancehed hydrocarbons 5. Conformation of cyclohexane and substituted cyclohexanes have been made and nmake the course live.

The course is very very interesting and progress gradually in a synchronised manner. This course is for one , who are suffering from Organophobia. If you are unable to visualize the concept , then this course is for you.

Any Student , who is joning the course will learn

1. Conformational Isomerism

2. Eclipsing Strain

3. Vander wall Strain

4. Ring Strain

5. Newman Projection Methods

6. Sawhorse Projection Methods

8. Conformations of Ethane , Butane , 2-Methylbutane, 2,2-Dimethylbutane, 2,2- Dimethylbutane, 2,3-Dimethylpentane

9. Conformations of Cyclohexane, Methyl cyclohexane, Dimethylcyclohexane

10. Conformation of 1,3-Butadiene, Propene, Acetaldehyde

11. Conformation of Compounds with H Bonding.

12 . Problem Solving & Molecular Properties.

In this course the Instructor has also provided an exercise for self practice of the student.

What's inside

Learning objectives

1. conformational isomerism
2. eclipsing strain
3. vander wall strain
4. ring strain
5. newman projection methods
6. sawhorse projection methods
7. conformations of ethane , butane , 2-methylbutane, 2,2-dimethylbutane, 2,2- dimethylbutane, 2,3-dimethylpentane

8. conformations of cyclohexane, methyl cyclohexane, dimethylcyclohexane
9. conformation of 1,3-butadiene,propene,acetaldehyde
10. conformation of compounds with h bonding.
11. problem solving & molecular properties.
12. problem set with answer.
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1. conformational isomerism
2. eclipsing strain
3. vander wall strain
4. ring strain
5. newman projection methods
6. sawhorse projection methods
7. conformations of ethane , butane , 2-methylbutane, 2,2-dimethylbutane, 2,2- dimethylbutane, 2,3-dimethylpentane
8. conformations of cyclohexane, methyl cyclohexane, dimethylcyclohexane
9. conformation of 1,3-butadiene,propene,acetaldehyde
10. conformation of compounds with h bonding.
11. problem solving & molecular properties.
12. problem set with answer.
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Syllabus

Introduction

Introduction to the Course

Introduction to Conformational Isomerism

Introduction to Isomerism ( structural and Stereo )

Traffic lights

Read about what's good

what should give you pause

and possible dealbreakers

Uses 3D animation to illustrate concepts like Newman and Fisher projections, which can greatly aid in visualizing and understanding conformational isomerism

Progresses gradually in a synchronized manner, making it suitable for those with a foundational understanding of chemistry to master conformational isomerism

Includes problem sets and discussions based on properties, offering opportunities to practice and apply knowledge of conformational isomerism

Aims to help those suffering from 'Organophobia' by improving their ability to visualize and understand complex concepts in organic chemistry

Covers a wide range of topics, including conformations of various alkanes, cycloalkanes, and compounds with hydrogen bonding, providing a comprehensive overview

Focuses on problem solving and molecular properties, which are essential for understanding and applying the principles of conformational isomerism

Reviews summary

Mastering conformational isomerism with 3d visuals

According to learners, this course is highly effective for understanding conformational isomerism, especially through its exceptional 3D animations. Students say these visuals are invaluable for visualizing molecules and make concepts crystal clear. The instructor's explanations are described as clear and step-by-step, helping learners master the topic. While the course requires basic chemistry, many found it a lifesaver for studies. Overall sentiment is overwhelmingly positive.

Minor disagreement on explanation speed.

"The instructor breaks down everything beautifully."

"Explanations are lucid."

"...some of the explanations a bit too fast or assumed prior knowledge I didn't have."

"Step-by-step approach is fantastic."

Not suitable for absolute beginners.

"It does assume a solid base in general and organic chemistry, so it's not for absolute beginners."

"Requires familiarity with basic organic chemistry concepts and nomenclature."

"...assumed prior knowledge I didn't have. Maybe I needed a stronger chemistry background..."

Highly effective for understanding isomerism.

"This course finally made conformational isomerism click for me."

"Perfect course for mastering conformational analysis."

"Helped me immensely with my university course."

"This course was a lifesaver."

Concepts are broken down effectively.

"The step-by-step approach to Newman and Sawhorse projections is fantastic."

"Explanations are lucid."

"The instructor breaks down everything beautifully."

"The instructor's approach finally made it intuitive."

Helps visualize complex molecular structures.

"Outstanding visualization tools for conformational analysis. The 3D animations make concepts crystal clear."

"Simply the best course for understanding 3D structures in organic chemistry."

"The interactive nature of the 3D models is unparalleled."

"If you have trouble visualizing molecules, this is your solution."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Stereochemistry III : Conformational Isomerism in 3D. with these activities:

Review Newman Projections

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Reinforce your understanding of Newman projections, a fundamental tool for visualizing and analyzing conformational isomers.

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Review the definition and purpose of Newman projections.
Practice converting between different representations of molecules.
Work through examples of identifying staggered and eclipsed conformations.

Read 'Organic Chemistry' by Vollhardt and Schore

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Expand your understanding of conformational isomerism with a comprehensive organic chemistry textbook.

View Organic Chemistry on Amazon

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Obtain a copy of 'Organic Chemistry' by Vollhardt and Schore.
Read the chapters on stereochemistry and conformational analysis.
Work through the example problems and exercises.

Conformational Analysis Practice

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Solidify your understanding of conformational analysis by working through practice problems involving different molecules.

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Find practice problems on conformational analysis online or in textbooks.
Draw Newman projections for various conformations of molecules.
Calculate the relative energies of different conformations.
Identify the most stable conformation of each molecule.

Four other activities

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Create a 3D Model of Cyclohexane Conformations

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Visualize cyclohexane conformations by building a 3D model to better understand ring flipping and substituent effects.

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Gather materials for building a 3D model (e.g., modeling kit, online software).
Construct models of chair, boat, and twist-boat conformations of cyclohexane.
Illustrate ring flipping and the interconversion of conformations.
Add substituents to the cyclohexane ring and analyze their effects on stability.

Presentation on Cyclohexane Conformations

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Create a presentation summarizing the different conformations of cyclohexane and their relative energies.

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Research the different conformations of cyclohexane (chair, boat, twist-boat).
Create slides with diagrams and explanations of each conformation.
Discuss the factors that affect the stability of each conformation.
Present your findings to a group of classmates or colleagues.

Read 'Stereochemistry of Organic Compounds' by Ernest L. Eliel and Samuel H. Wilen

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Deepen your knowledge of stereochemistry with a comprehensive graduate-level textbook.

View Stereochemistry of Organic Compounds on Amazon

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Obtain a copy of 'Stereochemistry of Organic Compounds' by Eliel and Wilen.
Read the chapters on conformational analysis and related topics.
Focus on the theoretical aspects and advanced concepts.

Tutor Students in Conformational Isomerism

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Reinforce your understanding by explaining conformational isomerism concepts to other students.

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Offer to tutor classmates or students in introductory organic chemistry courses.
Prepare explanations and examples of key concepts.
Answer questions and provide feedback on practice problems.

Career center

Learners who complete Stereochemistry III : Conformational Isomerism in 3D. will develop knowledge and skills that may be useful to these careers:

Molecular Modeler

The work of a Molecular Modeler involves utilizing computational tools and software to create accurate three dimensional models of molecules. This course helps build a foundation in understanding conformational isomerism, which is crucial for accurately representing molecules in silico. The course's emphasis on Newman and Sawhorse projection methods, along with the conformations of various alkanes and cycloalkanes, provides the necessary skills for building and interpreting molecular models, which should be particularly helpful for those working on drug design or materials science and seek an understanding of 3D molecular structures.

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Medicinal Chemist

Medicinal Chemists design and synthesize new pharmaceutical drugs. This course can be useful to medicinal chemists by deepening their understanding of conformational analysis, which is critical for understanding drug-receptor interactions. The course's focus on the conformations of various compounds, including those with hydrogen bonding, coupled with problem-solving exercises, helps build the skills needed to design molecules with specific three-dimensional shapes for optimal binding and efficacy. Those interested in rational drug design might find the course particularly relevant.

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Organic Chemist

An Organic Chemist studies the structure, properties, composition, reactions, and preparation of carbon-containing compounds. This course can provide a strong foundation in conformational isomerism, a fundamental concept in organic chemistry. The course's coverage of Newman and Sawhorse projections, torsional and Van der Waals strain, and the conformations of various alkanes and cycloalkanes directly contributes to a deeper understanding of molecular behavior and reactivity. The course may be of interest to organic chemists looking to refine their grasp of stereochemical principles and their applications.

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Polymer Chemist

Polymer Chemists specialize in the synthesis, characterization, and properties of polymers, which are large molecules made up of repeating subunits. This course helps build a foundation in the conformational analysis of molecules, which is relevant to understanding the properties of polymers. The knowledge gained about Van der Waals strain, torsional strain, and the conformations of various alkanes and cycloalkanes can provide insights into polymer chain flexibility and interactions. Polymer Chemists seeking a deeper understanding of how molecular conformations influence polymer behavior should find the course valuable.

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Science Teacher

Science Teachers educate students on scientific principles, fostering critical thinking and problem-solving skills. This course provides a deeper understanding of conformational isomerism, enhancing the teacher's ability to explain complex concepts clearly. The course's use of 3D animation to illustrate Newman and Fisher projections helps visualize abstract ideas, making them more accessible. Science teachers seeking to improve their instruction in organic chemistry may find this course invaluable.

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Research Scientist

A Research Scientist designs and conducts experiments to investigate scientific phenomena, often working in academic or industrial settings. This course may be useful to research scientists who work with molecules, providing them with a deeper understanding of conformational isomerism. The course's focus on visualizing molecular structures in three dimensions, understanding strain factors, and analyzing the conformations of various compounds might be especially useful for generating hypotheses and interpreting experimental data. Those pursuing research in organic chemistry, medicinal chemistry, or materials science may find the course particularly relevant.

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Materials Scientist

Materials Scientists research and develop new materials, often with specific properties tailored for various applications. A course such as this one can provide a key understanding of how molecular conformations affect the properties of materials. The course's detailed exploration of ring strain, Van der Waals strain, and the conformations of various cyclic and branched hydrocarbons can contribute to understanding the structure-property relationships in polymeric and other advanced materials. Materials Scientists seeking to design materials with specific properties should find the course particularly helpful.

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Computational Chemist

A Computational Chemist uses computer simulations to study chemical problems. This course may be useful by providing the understanding of conformational analysis and molecular properties required to develop or use appropriate computational models. Topics such as Van der Waals strain, intramolecular hydrogen bonding, and the conformations of various cyclic and acyclic compounds directly apply to building accurate computational models. Learners interested in this role should find the course's focus on visualizing and understanding molecular conformations especially helpful.

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Formulation Scientist

Formulation Scientists develop and optimize the composition of pharmaceutical, cosmetic, or food products to ensure stability, efficacy, and desired properties. This course provides insights into molecular conformations and interactions, which can be relevant to understanding the stability and behavior of formulations. The study of intramolecular hydrogen bonding and Van der Waals strain can help predict how different components in a formulation will interact with each other. Formulation scientists seeking to optimize product formulations might find this course beneficial.

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Chemical Engineer

Chemical Engineers apply the principles of chemistry, biology, physics, and mathematics to solve problems involving the production or use of chemicals, fuel, drugs, food, and many other products. The understanding of molecular conformations and their impact on physical properties, as taught in this course, may be useful in designing and optimizing chemical processes. Concepts such as Van der Waals strain and intramolecular hydrogen bonding can affect reaction rates and equilibrium. Chemical Engineers involved in process design or optimization may find this course helpful.

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Structural Biologist

Structural Biologists study the three-dimensional structure of biological macromolecules, such as proteins and nucleic acids, to understand their function. While this course focuses on smaller molecules, it may be useful by providing a foundational understanding of conformational analysis and molecular visualization. The course's teachings on Newman and Sawhorse projections, along with various conformations of organic molecules, can help structural biologists better appreciate the complexities of macromolecular structures and interactions. Those interested in learning about the building blocks of larger biological systems might find the course helpful.

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Patent Attorney

Patent Attorneys work with inventors to protect their intellectual property, including new chemical compounds or processes. While not directly related to legal practice, a course like this could aid in understanding the technical aspects of inventions involving molecular structures and conformations. The course's topics, such as stereoisomerism and molecular properties, can help understand the novelty and non-obviousness of a chemical invention. Patent attorneys specializing in chemical or pharmaceutical patents could find the course helpful.

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Regulatory Affairs Specialist

Regulatory Affairs Specialists ensure that products meet the requirements of regulatory agencies, such as the FDA, before they are released to market. This course may be useful if the regulatory affairs specialist is working with products that have a strong reliance on molecule conformations. The course emphasis on visualizing molecular structures in three dimensions and understanding strain factors would be transferable to methods of validating products for market. Those working with medical products may find the course helpful.

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Science Writer

Science Writers communicate complex scientific information to the public through articles, blog posts, or other media. This course may be useful by providing a more solid understanding of the underlying chemistry concepts related to molecular structure and properties. The course's explorations of conformational isomerism and three-dimensional visualization could help a science writer explain concepts more clearly and accurately. Science writers who cover topics in chemistry, biology, or medicine might find the course helpful.

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Data Scientist

Data Scientists analyze large datasets to extract meaningful insights and inform decision-making. This course may be useful if the data scientist is working in a field related to chemistry or materials science. The course's emphasis on visualizing molecular structures in three dimensions and understanding strain factors would be transferable to methods for visualizing data in other contexts. Those working with chemical or biological data may find the course helpful.

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Reading list

We've selected two books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Stereochemistry III : Conformational Isomerism in 3D..

Stereochemistry of Organic Compounds

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Classic and comprehensive resource on stereochemistry, including detailed discussions of conformational analysis. It is often used as a graduate-level textbook and is considered a definitive reference in the field. It provides in-depth coverage of the theoretical and experimental aspects of stereochemistry. This book is more valuable as additional reading for those seeking a deeper understanding of the subject.

Stereochemistry of Organic Compounds

Hardcover

$$$$

Organic Chemistry

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Provides a comprehensive overview of organic chemistry principles, including stereochemistry and conformational analysis. It widely used textbook in undergraduate organic chemistry courses. Reading relevant chapters will provide a solid foundation for understanding the concepts covered in this course. It is particularly helpful for students who need a more in-depth explanation of the underlying principles.