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Rebecca Lamason, Mary Ellen Wiltrout, Darcy Gordon, Monika Avello, Iain Cheeseman, Caitlin Friend, and Mingyu Yang

This is the first cell biology course in a three-part series. Building upon the concepts from biochemistry, genetics, and molecular biology from our 7.00x Introductory Biology and 7.05x Biochemistry MOOCs, these cell biology courses transition to a comprehensive discussion of biology at an experimental level. How do we know what we know about cells at a molecular level and how can we use that knowledge to design experiments to test hypotheses in cell biology?

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This is the first cell biology course in a three-part series. Building upon the concepts from biochemistry, genetics, and molecular biology from our 7.00x Introductory Biology and 7.05x Biochemistry MOOCs, these cell biology courses transition to a comprehensive discussion of biology at an experimental level. How do we know what we know about cells at a molecular level and how can we use that knowledge to design experiments to test hypotheses in cell biology?

Professors Rebecca Lamason and Iain Cheeseman guide you through a learning experience where you will discover experiments that answered big questions and find out what is still on the horizon. You will embark on a lively journey through cellular transport and cellular signaling mechanisms and regulation and learn how to apply key concepts and themes of this dynamic experimental science to understand the fundamental workings of cells.

We developed the 7.06x Cell Biology series with an emphasis on:

  • Developing your scientific thinking skills including articulating hypotheses, performing thought experiments, interpreting data, and designing experiments.
  • Using data based on real scientific experiments and highlighting the scientific process in assessments.
  • Asserting that biology is an active field that changes daily through examples of research and relevance to medicine, not static information in a textbook.
  • Uniting themes and principles that inform how scientists conduct and interpret research.
  • Exploring foundational experiments that defined modern cell biology.
  • Implementing the science of learning in the course design.

What you'll learn

  1. How to apply biochemical and genetic approaches to address fundamental questions of transport and signaling in the cell.
  2. How to evaluate the conclusions and models that scientists develop about cell biology from experimental approaches and results.
  3. How to select specific empirical methods and techniques based on the different kinds of questions scientists ask.
  4. How to design experiments to answer cell biology experiments with proper controls.
  5. How to assess biological necessity and sufficiency from experimental results.
  6. How to compare and contrast protein transport and signaling pathways processes.
  7. How to identify recurring themes in protein transport and signal transduction.

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What's inside

Learning objectives

  • How to apply biochemical and genetic approaches to address fundamental questions of transport and signaling in the cell.
  • How to evaluate the conclusions and models that scientists develop about cell biology from experimental approaches and results.
  • How to select specific empirical methods and techniques based on the different kinds of questions scientists ask.
  • How to design experiments to answer cell biology experiments with proper controls.
  • How to assess biological necessity and sufficiency from experimental results.
  • How to compare and contrast protein transport and signaling pathways processes.
  • How to identify recurring themes in protein transport and signal transduction.

Syllabus

Membranes, Lipids, and Proteins
Intracellular Transport and Protein Secretion
Nuclear-Cytoplasmic Transport
Principles of Signal Transduction
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Signaling Pathways and Regulatory Paradigms

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Challenges learners to think critically and articulate hypotheses, interpret data, and design experiments
Features real scientific experiments, highlighting the scientific process and its significance
Emphasizes the dynamic nature of biology and its relevance to medicine
Integrates unifying themes and principles that guide scientific inquiry
Examines foundational experiments that have shaped modern cell biology
Incorporates the science of learning into the course design to enhance comprehension

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Reviews summary

Well-received cell transport and signaling course

Learners say this informative, engaging course on Cell Biology: Transport and Signaling is well-taught by experienced instructors. With clear explanations and real-life experiments, students recommend this course for bio-related fields and those interested in cell biology.
Course can be challenging, but rewarding.
"The description of transport in the cell is precise and easily understandable. The process is magical."
"This was an interesting course that kept my interest and provided a mild challenge."
"It went a little fast..."
Course is beneficial for those in bio-related fields.
"I strongly recommend this course to those interested in or working in any bio-related field."
"I encourage all young students in Biology to take this course."
"I really love the MITx courses because of the way they provide material."
Instructors are experienced and knowledgeable.
"Well structured course and accessible with experienced teachers practitioners, what else?"
"The course content is great and the professor is a great teacher!"
"Everything is explained very well with deep understanding and clarification of concepts."
Lectures are clear and interesting, using real-life experiments.
"Amazing course with lots of good information. This course really helps understand the content with many in depth diagrams, animations, and lectures."
"The instructors are always inviting us to think scientifically about the system under study."
"They show real experiments that have unraveled the mechanisms explained, and invite us to design new experiments."
Chapter end quizzes are difficult and require understanding of hypothetical experiments.
"But when it comes to the chapter end quizzes, a lot of questions are based on hypothetical experiments."
"I think I have a hard time trying to figure out what the different entities involved in the experiments are."
"It would help if it described the experiments in the quizzes in more detail, like having more picture illustrations."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Cell Biology: Transport and Signaling with these activities:
Experiment Design Practice
Build a solid foundation in experimental design principles, a crucial skill for understanding and conducting cell biology research.
Browse courses on Experimental Design
Show steps
  • Review principles of hypothesis testing, independent and dependent variables, and controls
  • Participate in online tutorials or workshops on designing scientific experiments
  • Practice designing experiments to test different research questions related to cell biology
Protein Transport and Signaling Exercises
Strengthen your understanding of protein transport and signaling mechanisms through targeted exercises.
Show steps
  • Solve practice problems on protein sorting, vesicle trafficking, and membrane transport mechanisms
  • Analyze experimental data on cell signaling pathways and identify key components and interactions
  • Participate in online quizzes and simulations to test your knowledge of protein transport and signaling
Cell Biology Techniques Explorations
Expand your knowledge of experimental techniques and methodologies used in cell biology research.
Show steps
  • Follow online tutorials on microscopy techniques, such as fluorescence microscopy and electron microscopy
  • Explore resources and documentation on molecular biology techniques, such as PCR, Western blotting, and gene editing
  • Attend workshops or webinars on flow cytometry and data analysis techniques
Two other activities
Expand to see all activities and additional details
Show all five activities
Science Communication Challenge
Develop your ability to effectively communicate complex scientific concepts in cell biology to a broad audience.
Browse courses on Science Communication
Show steps
  • Participate in science communication competitions or challenges
  • Create a short video or presentation that explains a cell biology concept in an engaging and accessible way
  • Write a blog post or article that summarizes current research findings in cell biology for a general audience
Cell Biology Research Proposal Outline
Develop a strong foundation for future research endeavors by outlining a research proposal in cell biology.
Browse courses on Research Proposal
Show steps
  • Identify a specific research question or hypothesis related to cell biology
  • Conduct a literature review to support your research question and identify relevant experimental approaches
  • Outline the experimental design, including methods, expected outcomes, and potential implications
  • Seek feedback from instructors or peers on your research proposal outline

Career center

Learners who complete Cell Biology: Transport and Signaling will develop knowledge and skills that may be useful to these careers:
Professor
A Professor teaches and conducts research at a college or university. This course provides a foundation in the key concepts and techniques used in cell biology. This knowledge can help Professors develop and deliver engaging and informative lectures and design and conduct research projects.
Research Scientist
A Research Scientist conducts research to advance the understanding of natural phenomena. This course provides a foundation in the approaches and techniques used in cell biology research. This knowledge can help Research Scientists design and conduct experiments, interpret data, and develop models to better understand cellular processes.
Cell Biologist
A Cell Biologist studies the structure and function of cells, the basic unit of life. This course provides a foundation in the key concepts and techniques used in cell biology, including protein transport, signaling pathways, and regulatory mechanisms. This knowledge can help Cell Biologists design and conduct experiments, interpret data, and develop models to better understand cellular processes.
Medical Scientist
A Medical Scientist conducts research to advance the understanding of human health and disease. This course provides a foundation in the approaches and techniques used in cell biology research. This knowledge can help Medical Scientists design and conduct experiments, interpret data, and develop models to better understand cellular processes and their role in human health and disease.
Molecular Biologist
A Molecular Biologist studies the molecular basis of life. This course provides a foundation in the molecular and genetic approaches used to address fundamental questions of transport and signaling in the cell. This knowledge can help Molecular Biologists design and conduct experiments, interpret data, and develop models to better understand cellular processes.
Biochemist
A Biochemist studies the chemical processes that occur within living organisms. This course provides a foundation in the biochemical and genetic approaches used to address fundamental questions of transport and signaling in the cell. This knowledge can help Biochemists design and conduct experiments, interpret data, and develop models to better understand cellular processes.
Computational Biologist
A Computational Biologist uses computational tools and techniques to study biological systems. This course provides a foundation in the approaches and techniques used to study cellular processes using computational models. This knowledge can help Computational Biologists develop and use models to better understand the dynamics and regulation of cellular processes.
Geneticist
A Geneticist studies the genes and heredity of organisms. This course provides a foundation in the genetic approaches used to address fundamental questions of transport and signaling in the cell. This knowledge can help Geneticists design and conduct experiments, interpret data, and develop models to better understand cellular processes.
Science Writer
A Science Writer communicates complex scientific information to a non-scientific audience. This course provides a foundation in the key concepts and techniques used in cell biology. This knowledge can help Science Writers accurately and effectively communicate the latest advances in cell biology research to the public.
Toxicologist
A Toxicologist studies the effects of toxic substances on living organisms. This course provides a foundation in the approaches and techniques used to study the transport and signaling of toxic substances in cells. This knowledge can help Toxicologists design and conduct experiments, interpret data, and develop models to better understand the effects of toxic substances on cellular processes.
Laboratory Technician
A Laboratory Technician conducts experiments and analyzes data in a laboratory setting. This course provides a foundation in the key concepts and techniques used in cell biology. This knowledge can help Laboratory Technicians perform experiments accurately and efficiently and interpret data correctly.
Pharmacologist
A Pharmacologist studies the effects of drugs on living organisms. This course provides a foundation in the approaches and techniques used to study drug transport and signaling in cells. This knowledge can help Pharmacologists design and conduct experiments, interpret data, and develop models to better understand the effects of drugs on cellular processes.
Biomedical Engineer
A Biomedical Engineer designs and develops medical devices and technologies. This course provides a foundation in the cellular and molecular basis of human health and disease. This knowledge can help Biomedical Engineers design and develop devices and technologies that are more effective and less invasive.
Physician
A Physician diagnoses and treats diseases in humans. This course provides a foundation in the cellular and molecular basis of human health and disease. This knowledge can help Physicians better understand the causes and mechanisms of diseases and develop more effective treatments.
Veterinarian
A Veterinarian diagnoses and treats diseases in animals. This course provides a foundation in the cellular and molecular basis of animal health and disease. This knowledge can help Veterinarians better understand the causes and mechanisms of diseases and develop more effective treatments.

Reading list

We've selected 14 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Cell Biology: Transport and Signaling.
A classic textbook that provides a comprehensive overview of cell biology, including topics covered in this course, such as membrane transport, intracellular transport, and signal transduction.
A textbook that focuses on the principles of cell signaling, including topics such as receptor-ligand interactions, signal transduction pathways, and the regulation of cell behavior.
A comprehensive textbook that covers a wide range of topics in cell and molecular biology, including cell structure and function, metabolism, genetics, and development.
A textbook that provides a comprehensive overview of biochemistry, including topics such as protein structure and function, metabolism, and molecular biology.
A classic textbook that provides a comprehensive overview of molecular biology, including topics such as gene expression, protein synthesis, and cell cycle regulation.
A concise textbook that provides an overview of cell biology, including topics such as cell structure and function, cell cycle regulation, and signal transduction.
A textbook that focuses on the biochemistry and molecular biology of plants, including topics such as photosynthesis, respiration, and plant development.
A textbook that focuses on the developmental biology of animals, including topics such as embryonic development, organogenesis, and regeneration.
A concise textbook that provides an overview of immunology, including topics such as the immune system, immune responses, and immune disorders.
A textbook that focuses on the molecular, cellular, and systems biology of the nervous system, including topics such as neuron structure and function, synaptic transmission, and neural development.
A textbook that focuses on the principles of virology, including topics such as virus structure, virus replication, and virus-host interactions.

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