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饶毅

《生物学概念与途径》课程由饶毅2008年在北京大学设立和主持,面向所有大学生和研究生,目的是让年轻的学生了解生物学历史上,一些重要的概念是如何提出的,一些重要的途径和方法是如何用来解决重要且有深刻意义的生物学问题的。

大部分内容由饶毅讲授,带着大家一起解读1866年孟德尔的遗传学论文,解读1910年摩尔根的果蝇论文,解读1944年Avery、McLeod、McCarty如何提出DNA是遗传物质的论文。这些经典性的工作,让我们从思想上理解科学研究是怎么做的。

北京大学物理系的汤超教授、哈佛大学的谢晓亮教授、北京生命科学研究所的王晓东教授、北京大学化学院何川教授、清华大学的施一公教授、北京大学的植物生物学的邓兴旺教授和顾红雅教授,分别从物理的定量、化学与生物的交叉、生物化学的经典实验、化学角度的生物大分子、结构生物学、现代农业生物技术与种业发展、驱动演化的“力”等多学科,多角度讲授重要的概念和途径。

本课程重思想,重交叉,重培养学生的科学能力;培养科学研究的价值观(比如判断什么是好的科学),力求为未来科学探索树立参照系;老师提供一个起点,能看的多深,发展多远,取决于同学们的天赋和努力。

希望大家通过我们的慕课有所收获。

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What's inside

Syllabus

导言-饶毅
本节课程对《生物学概念和途径》的内容、目的、要求进行了理念性的介绍。这门课由饶毅、王晓东、施一公、谢晓亮、邓兴旺、汤超、何川、鲁白、顾红雅教授主讲。课程要求学生读原始文献,让学生了解生物学概念的产生,理解实验设计,分析和思考。
孤独的天才—孟德尔 -饶毅
他孤立于当时的科学界,做出奠基性突破却终生未被学界承认;他的工作几十年后尚不为同一学科第二重要的科学家、诺贝尔奖得主所理解;他发现的貌似简单的理论,即使在今天多数学过的人,都没意识到其智力高度;他不是为利益做研究的纯粹科学家,身后却被疑造假,再遭遇不公。这位孤独的天才,就是自称为“实验物理学教师”的遗传学之父:孟德尔。饶毅教授作为全世界了解孟德尔最多的活着的人,故事性地介绍了孟德尔的生前身后的故事、发表的论文,重点介绍了孟德尔做的研究工作,包括其如何选择试验材料,研究的分工安排,解决途径和思维方法等。
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Traffic lights

Read about what's good
what should give you pause
and possible dealbreakers
该课程由饶毅教授授课,饶毅教授是北京大学教授,中国科学院院士,长期从事生物学研究,在神经生物学、发育生物学、免疫学等领域取得了突出成就。
本课程重在培养学生的科学思维能力、实验设计能力、分析问题能力和解决问题能力。
本课程内容丰富,涉及生物学多个领域,能够帮助学生拓宽知识面,加深对生物学的理解。
本课程邀请了多位知名专家学者授课,他们的专业知识和教学经验能够为学生提供高质量的学习体验。
本课程提供在线学习平台,学生可以随时随地学习,不受时间和空间限制。
本课程免费提供,为学生提供了低成本的学习机会。

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Reviews summary

生物学经典概念与研究方法

根据学生反馈,这门北京大学教授主讲生物学概念与途径课程,因其深入探讨生物学经典概念的起源科学研究的思维方法而受到部分学员高度赞扬。课程通过阅读原始文献,提供了独特的历史视角,帮助理解重要科学发现的过程。然而,也有学生反映课程内容偏向理论和历史,对于现代生物技术覆盖不足,且原始文献的阅读挑战较大对初学者不太友好。总的来说,课程更适合对科学史和研究方法感兴趣、有一定基础的学术导向型学习者。
学习方法独特但有挑战
"尤其是阅读经典文献的部分,非常有启发性。"
"原始文献很难读懂..."
"阅读原始文献的挑战比较大,但完成后确实有收获。"
讲课内容有深度且启发性
"各位教授的讲解充满智慧。"
"各位老师都是领域的大家,讲课内容很有深度。"
对生物学基础概念挖掘深
"这门课对生物学的历史概念和研究方法讲得很深入,非常有启发性。"
"课程的视角非常独特,让我对生物学研究产生了浓厚的兴趣。"
对初学者或需背景知识
"感觉更适合有一定基础且志在学术研究的人,对普通学生...不太友好。"
"课程节奏比较快,有些地方需要自己花很多时间去查资料。"
"原始文献的阅读挑战较大..."
对现代技术覆盖相对较少
"课程内容太偏重历史和理论,对现代生物技术的介绍不够。"
"课程内容太老了,还在讲孟德尔和摩尔根。现在生物学发展这么快..."
"感觉不太实用..."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in 生物学概念与途径 with these activities:
Find a mentor in the field of genetics
Gain personalized guidance and insights by connecting with an experienced professional in genetics.
Browse courses on Genetics
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  • Identify potential mentors through professional organizations, universities, or research institutions.
  • Reach out to your potential mentors and express your interest in their mentorship.
Review basic algebra and trigonometry
Brush up on your algebra and trigonometry skills to enhance your understanding of the quantitative aspects of genetics.
Browse courses on Algebra
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  • Review your notes or a textbook on algebra and trigonometry.
  • Solve practice problems to reinforce your understanding.
Read Mendel's 1866 paper on inheritance
Reinforce your understanding of the concepts of inheritance by reading the seminal work in the field.
Show steps
  • Read the original paper in its entirety.
  • Summarize the key findings of the paper in your own words.
  • Discuss the implications of Mendel's work for our understanding of genetics.
Five other activities
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Show all eight activities
Read Morgan's 1910 paper on the genetics of the fruit fly
Deepen your understanding of the role of chromosomes in heredity by reviewing this groundbreaking work.
Show steps
  • Read the original paper in its entirety.
  • Summarize the key findings of the paper in your own words.
  • Discuss the implications of Morgan's work for our understanding of genetics.
Create a diagram of the structure of DNA
Solidify your understanding of the structure of DNA by creating a visual representation.
Browse courses on DNA
Show steps
  • Research the structure of DNA using credible sources.
  • Choose a diagram format that clearly represents the key features of DNA.
  • Create your diagram, labeling the different components of DNA.
Practice solving genetics problems
Sharpen your problem-solving skills by practicing genetics problems.
Browse courses on Genetics
Show steps
  • Find a collection of genetics problems of varying difficulty levels.
  • Solve the problems, showing your work and explaining your reasoning.
  • Check your answers and identify areas where you need improvement.
Write a paper on the history of genetics
Expand your knowledge of genetics by researching and writing about its historical development.
Browse courses on Genetics
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  • Research the history of genetics, focusing on key discoveries and milestones.
  • Organize your research into a coherent outline.
  • Write a paper that presents your findings in a clear and concise manner.
Volunteer at a genetics research lab
Gain hands-on experience and contribute to the field of genetics by volunteering in a research lab.
Browse courses on Genetics
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  • Research genetics research labs in your area and identify potential volunteer opportunities.
  • Contact the labs and inquire about volunteer positions.
  • Attend the volunteer orientation and training.

Career center

Learners who complete 生物学概念与途径 will develop knowledge and skills that may be useful to these careers:
Molecular Biologist
A Molecular Biologist studies the structure and function of biological molecules. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Molecular Biologist. The course's coverage of topics such as molecular biology, genetics, and biochemistry would also be particularly relevant to this role.
Geneticist
A Geneticist studies genes and their role in inheritance and disease. The course's focus on genetics and its role in biology would provide a strong foundation for a Geneticist. The course's coverage of topics such as molecular biology, genetics, and genomics would also be particularly relevant to this role.
Clinical Geneticist
A Clinical Geneticist uses genetic information to diagnose and treat diseases. The course's focus on genetics and its role in biology would provide a strong foundation for a Clinical Geneticist. The course's coverage of topics such as molecular biology, genetics, and genomics would also be particularly relevant to this role.
Biostatistician
A Biostatistician applies statistical methods to a wide range of biological problems. Their work helps build a foundation for scientific discovery by extracting meaningful insights from complex data. The course's focus on biological concepts and pathways would be particularly relevant to a Biostatistician, providing a strong understanding of the biological context in which they work.
Microbiologist
A Microbiologist studies microorganisms and their role in the environment and human health. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Microbiologist. The course's coverage of topics such as microbiology, immunology, and molecular biology would also be particularly relevant to this role.
Biomedical Engineer
A Biomedical Engineer designs and builds devices and systems to solve problems in biology and medicine. The course's emphasis on understanding biological concepts and pathways would provide a solid foundation for a Biomedical Engineer. The course's focus on the history and development of scientific discovery would also be helpful for understanding the context of their work.
Epidemiologist
An Epidemiologist investigates the causes and distribution of diseases. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for an Epidemiologist. The course's coverage of topics such as epidemiology, biostatistics, and public health would also be particularly relevant to this role.
Cell Biologist
A Cell Biologist studies the structure and function of cells. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Cell Biologist. The course's coverage of topics such as cell structure, cell division, and cell signaling would also be particularly relevant to this role.
Computational Biologist
A Computational Biologist develops and uses computational tools to solve problems in biology. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Computational Biologist. The course's coverage of topics such as bioinformatics, genomics, and systems biology would also be particularly relevant to this role.
Medical Physicist
A Medical Physicist applies the principles of physics to medicine. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Medical Physicist. The course's coverage of topics such as radiation therapy, medical imaging, and nuclear medicine would also be particularly relevant to this role.
Pharmacologist
A Pharmacologist studies the effects of drugs on the body. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Pharmacologist. The course's coverage of topics such as pharmacology, molecular biology, and physiology would also be particularly relevant to this role.
Developmental Biologist
A Developmental Biologist studies the development of organisms. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Developmental Biologist. The course's coverage of topics such as embryology, developmental genetics, and developmental biology would also be particularly relevant to this role.
Immunologist
An Immunologist studies the immune system and its role in fighting disease. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for an Immunologist. The course's coverage of topics such as immunology, molecular biology, and cell biology would also be particularly relevant to this role.
Biophysicist
A Biophysicist applies the principles of physics to biological systems. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Biophysicist. The course's coverage of topics such as molecular structure, protein folding, and bioenergetics would also be particularly relevant to this role.
Cancer Researcher
A Cancer Researcher studies the causes, development, and treatment of cancer. The course's emphasis on understanding biological concepts and pathways would provide a strong foundation for a Cancer Researcher. The course's coverage of topics such as molecular biology, genetics, and cell signaling would also be particularly relevant to this role.

Reading list

We've selected eight books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in 生物学概念与途径.
这本英文教科书提供发育生物学的全面概述,强调概念和机制,有助于理解胚胎发育和形态形成。
这本英文教科书提供生物学的全面概述,涵盖了从分子到生态系统的广泛主题。
这本英文教科书为生物学提供了更简明扼要的概述,涵盖了广泛的主题,重点关注概念理解。
这本英文教科书提供遗传学的全面概述,涵盖了经典概念和最新进展。

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