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Introduction to Systems Biology

Systems Biology and Biotechnology,

This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses.

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Rating 3.8 based on 90 ratings
Length 11 weeks
Effort 6-8 hours/week
Starts Dec 7 (6 weeks ago)
Cost $49
From Icahn School of Medicine at Mount Sinai via Coursera
Instructor Ravi Iyengar, PhD
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Biology Basic Science

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What people are saying

field of systems biology

This course tries to give an overview about the thrilling field of Systems Biology and simultaneously it tries to introduce you to the state of the art.

Professor The instructor, Ravi Iyengar, is clearly a distinguished researcher and current pioneer in the emerging field of systems biology.

The course is sort of a bird's eye view of the field of systems biology such that a beginner would not understand much of anything and an experienced researcher would also not really benefit from it either.

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ravi iyengar

Although I am thankful to the Icahn School of Medicine at Mount Sinai, Ravi Iyengar & colleagues and especially Coursera for providing the such courses online, I have to say after taking this course that I did not find this helpful and would not really recommend it to anyone.

Thanks to Dr Ravi Iyengar for the talks and his team for the course.

Professor Ravi Iyengar is very clear and has a broad knowledge of Systems Biology.

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system biology

It's really a nice introduction of system biology.

I think the difficulty arose from the fact that Dr. Iyer would teach a concept, all the while peppering some targeted comments about some cellular entity here and there, which in the normal course of conversations, I would forget because I was looking for the general models of system biology.

The course is basically for advanced students who do scientific research in this system biology field.

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so much

Thanks so much!

It's a great overview, but somehow i didn't feel like it stuck even though i did put in effort to read the articles assigned starting halfway through the course.Maybe it's because there's so much material that will be covered in a hands on part in the 3rd and 4th parts of this specialization... Would definitely recommend it to everyone interested in biotechnology and systems biology.

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Careers

An overview of related careers and their average salaries in the US. Bars indicate income percentile.

Cellular Phone Technician $57k

Cellular Biologist $65k

Division Chair, Cellular and Molecular Pathogenesis $70k

Cellular Neuroscientist (BS or MS) $71k

Cellular Sales Rep Manager $76k

Senior Cellular Installation and Testing $78k

Molecular and Cellular Biology Program Manager $90k

Cellular Networks Support Engineer $93k

Cellular Field Engineer Manager $103k

Molecular Scientist - Target Biology and Cellular Profiling $106k

Cellular Test Software Engineer $118k

Associate Adjunct Professor Biochemistry and Molecular & Cellular Biology $119k

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Rating 3.8 based on 90 ratings
Length 11 weeks
Effort 6-8 hours/week
Starts Dec 7 (6 weeks ago)
Cost $49
From Icahn School of Medicine at Mount Sinai via Coursera
Instructor Ravi Iyengar, PhD
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Biology Basic Science

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