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Neuroscience Reconstructed

Genetics and Development

Johannes Gräff, Gioele La Manno, Liliane Tenenbaum, Elsa Pellet, and Sean Hill

Modern neuroscience is multidisciplinary and collaborative. We need to integrate knowledge of experimental and theoretical approaches to neuroscience, and look at the brain and brain function from different perspectives: for example, genes can partially explain differences in reading ability, but there is no single gene that makes someone a good or a poor reader. And genes can be turned on and off by external factors such as someone’s diet or a virus infection. So to understand something as complex as reading ability, we need to stitch together knowledge about the role of genes, proteins, cells, and large networks of cells.

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Modern neuroscience is multidisciplinary and collaborative. We need to integrate knowledge of experimental and theoretical approaches to neuroscience, and look at the brain and brain function from different perspectives: for example, genes can partially explain differences in reading ability, but there is no single gene that makes someone a good or a poor reader. And genes can be turned on and off by external factors such as someone’s diet or a virus infection. So to understand something as complex as reading ability, we need to stitch together knowledge about the role of genes, proteins, cells, and large networks of cells.

In this course on Genetics and Brain Development, we will focus on the principles of neurogenetics and brain development and we will introduce you to the fields of genomics, transcriptomics, epigenomics and their applications.

What's inside

Learning objective

You will learn from top scientists, specialised in each field, and have access to research databases and learning resources such as brain atlases and brain modeling tools. we aim to show you how these new tools can help integrate the vast amounts of neuroscience data available to innovate medical technologies and therapies. and we will teach you how to use these tools for your own research and understanding.

Syllabus

week 1: Basics of gene expression
week 2: Genetic variation, gene networks and epigenetic
week 3: Genome, epigenome and transcriptome
week 4: Overview of embryonic development
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week 5: The birth of the nervous system
week 6: Methods and tools in genetics
week 7: Gene therapy in the nervous system
week 8: Introduction to big data
week 9: Introduction to modelling in neuroscience

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Taught by instructors from top institutions like EPFL and CNRS
Provides a strong foundation for those interested in the genetic and molecular basis of brain development
Incorporates hands-on tools and resources, such as brain atlases and modeling tools, to enhance learning
Covers up-to-date research in genetics, genomics, and brain development
Provides an overview of gene therapy in the nervous system and its potential applications
Recommended for students with a background in biology, genetics, or related fields

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Activities

Coming soon We're preparing activities for Neuroscience Reconstructed: Genetics and Development. These are activities you can do either before, during, or after a course.

Career center

Learners who complete Neuroscience Reconstructed: Genetics and Development will develop knowledge and skills that may be useful to these careers:
Neurosurgeon
A Neurosurgeon operates on the brain and spinal cord. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the anatomy and function of the nervous system, which is essential for performing surgery.
Neuroscientist
A Neuroscientist studies the nervous system. They investigate how the brain, spinal cord, and nerves work together to control thought, emotion, and behavior. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. It also introduces them to the fields of genomics, transcriptomics, epigenomics and their applications.
Neurologist
A Neurologist diagnoses and treats diseases of the nervous system. This includes the brain, spinal cord, and nerves. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the causes and treatments for neurological diseases.
Geneticist
A Geneticist studies genes and heredity. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the role of genes in brain development and function.
Genetic Counselor
A Genetic Counselor provides information and support to individuals and families affected by genetic disorders. This includes disorders of the nervous system. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the causes and treatments for genetic neurological disorders.
Medical Geneticist
A Medical Geneticist specializes in the diagnosis and management of genetic disorders. This includes disorders of the nervous system. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the causes and treatments for genetic neurological disorders.
Pharmacologist
A Pharmacologist studies the effects of drugs on the body. This includes drugs that are used to treat neurological disorders. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the mechanisms of action of drugs that are used to treat neurological disorders.
Toxicologist
A Toxicologist studies the effects of toxins on the body. This includes toxins that can damage the nervous system. This course helps someone in this role by providing a foundation in the principles of neurogenetics and brain development. This helps them to better understand the mechanisms of action of toxins that can damage the nervous system.
Epidemiologist
An Epidemiologist studies the distribution and determinants of health-related states or events (including disease), and the application of this study to the control of diseases and other health problems. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better understand the causes and risk factors for neurological disorders.
Biostatistician
A Biostatistician applies statistical methods to the design, analysis, and interpretation of biomedical research studies. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better design and analyze studies on the causes and treatments of neurological disorders.
Science Editor
A Science Editor edits scientific and technical writing. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better understand the content of scientific papers and to edit them for clarity and accuracy.
Science Writer
A Science Writer writes about science and technology for a general audience. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better understand and write about the latest advances in neuroscience.
Science Teacher
A Science Teacher teaches science to students at the elementary, secondary, or post-secondary level. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better teach their students about the nervous system and its functions.
Science Policy Analyst
A Science Policy Analyst analyzes and evaluates scientific and technical information to inform policy decisions. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better understand the scientific basis for policy decisions related to neuroscience.
Science Communicator
A Science Communicator communicates science to the public. This course may be useful to someone in this role by providing a foundation in the principles of neurogenetics and brain development. This could help them to better understand and communicate the latest advances in neuroscience to the public.

Reading list

We've selected ten books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Neuroscience Reconstructed: Genetics and Development.
This textbook provides a comprehensive overview of the molecular biology of the cell, covering topics such as gene expression, DNA replication, and cell signaling. It valuable resource for students and researchers in the field of neuroscience.
This textbook provides a comprehensive overview of the principles of neuroscience, covering topics such as the structure and function of the nervous system, neural development, and neural plasticity. It valuable resource for students and researchers in the field of neuroscience.
This comprehensive textbook provides an in-depth overview of molecular biology, including genetics, genomics, and epigenetics. It valuable resource for students and researchers in neuroscience and related fields.
Provides a comprehensive overview of the development of the nervous system, covering topics such as neural induction, neural tube closure, and the formation of the brain and spinal cord. It valuable resource for students and researchers in the field of neuroscience.
This textbook provides a comprehensive overview of the field of embryology, covering topics such as embryonic development, organogenesis, and developmental genetics. It valuable resource for students and researchers in the field of neuroscience.
Provides an in-depth overview of epigenetic mechanisms of gene regulation, including topics such as DNA methylation, histone modifications, and non-coding RNAs.
Provides a general overview of epigenetics, including topics such as the role of epigenetics in development, disease, and evolution.
Provides a comprehensive overview of the field of big data, covering topics such as data storage, data analysis, and the use of big data in various fields. It valuable resource for students and researchers in the field of neuroscience.
This textbook provides an overview of molecular neuropharmacology, the study of the molecular mechanisms of drugs that affect the nervous system.

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