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Dr. Richard W. Neu and Dr. J. Carson Meredith

This course is an introduction to high-throughput experimental methods that accelerate the discovery and development of new materials.

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This course is an introduction to high-throughput experimental methods that accelerate the discovery and development of new materials.

It is well recognized that the discovery of new materials is the key to solving many technological problems faced by industry and society. These problems include energy production and utilization, carbon capture, tissue engineering, and sustainable materials production, among many others. This course will introduce the learner to a remarkable new approach to materials discovery and characterization: high-throughput materials development (HTMD).

Engineers and scientists working in industry, academic or government will benefit from this course by developing an understanding of how to apply one element of HTMD, high-throughput experimental methods, to real-world materials discovery and characterization problems. Internationally leading faculty experts will provide a historical perspective on HTMD, describe preparation of ‘library’ samples that cover hundreds or thousands of compositions, explain techniques for characterizing the library to determine the structure and various properties including optical, electronic, mechanical, chemical, thermal, and others. Case studies in energy, transportation, and biotechnology are provided to illustrate methodologies for metals, ceramics, polymers and composites.

The Georgia Tech Institute for Materials (IMat) developed this course in order to introduce a broad audience to the essential elements of the Materials Genome Initiative. Other courses will be offered by Georgia Tech through Coursera to concentrate on integrating (i) high-throughput experimentation with (ii) modeling and simulation and (iii) materials data sciences and informatics.

After completing this course, learners will be able to

• Identify key events in the development of High-Throughput Materials Development (HTMD)

• Communicate the benefits of HTMDwithin your organization.

• Explain what is meant by high throughput methods (both computational and experimental), and their merits for materials discovery/development.

• Summarize the principles and methods of high throughput creation/processing of material libraries (samples that contain 100s to 1000s of smaller samples).

• State the principles and methods for high-throughput characterization of structure.

• State the principles and methods for high throughput property measurements.

• Identify when high-throughput screening (HTS) will be valuable to a materials discovery effort.

• Select an appropriate HTS method for a property measurement of interest.

• Identify companies and organizations working in this field and use this knowledge to select appropriate partners for design and implementation of HTS efforts.

• Apply principles of experimental design, library synthesis and screening to solve a materials design challenge.

• Conceive complete high-throughput strategies to obtain processing-structure-property (PSP) relationships for materials design and discovery.

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What's inside

Syllabus

Welcome
What you should know before you start the course
Introduction
Frame the grand problem of materials design and how the Materials Genome Initiative approach, which encompasses high-throughput computational and experimental techniques as essential elements, will accelerate materials discovery and development. Provide a historical perspective and future outlook.
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Library Preparation
This module covers methods to experimentally generate discrete or gradient material libraries for interrogating the influence of composition or microstructure on properties; various process and synthesis methods for different classes of materials are considered
High-Throughput Characterization of Composition and Structure
This module covers techniques suitable for measuring the elemental composition and the structure in the material libraries; techniques for different classes of materials are considered.
High-Throughput Property Measurements
This module covers techniques to experimentally conduct property measurements suitable for high-throughput screening; optical, electronic, mechanical, chemical, and thermal properties are considered.
Applications
This module illustrates several applications of HTMD covering a range of material classes, properties, industrial sectors, and maturity levels.

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Engineers and scientists working in industry, academic or government will benefit from this course by developing an understanding of how to apply one element of HTMD, high-throughput experimental methods, to real-world materials discovery and characterization problems
Taught by Dr. Richard W. Neu and Dr. J. Carson Meredith, who are recognized within the field of materials science
Provides a historical perspective on High-Throughput Materials Development (HTMD)
Covers a range of material classes, properties, industrial sectors, and maturity levels
Helps learners identify when high-throughput screening (HTS) will be valuable to a materials discovery effort
Leads learners through selecting an appropriate HTS method for a property measurement of interest

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Reviews summary

Introductory materials development

According to students, Introduction to High-Throughput Materials Development offers a great amount of literature review and introductory explanation on HT. The course is well-received by learners.

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Introduction to High-Throughput Materials Development with these activities:
Review materials on experimental methods
Brush up on the fundamentals of experimental methods in materials science to prepare for this course.
Show steps
  • Review lecture notes or textbooks on experimental methods.
  • Solve practice problems or review examples of experimental design.
Review Calculus
Calculus is used in many places in materials science to model behavior, predict properties, and optimize design. Reviewing the basics of this topic will help solidify the learning foundational skills in this course.
Browse courses on Calculus
Show steps
  • Review basic derivatives and integrals
  • Apply simple calculus to modeling a materials problem
Complete the tutorials on the Georgia Tech High-Throughput Materials Development (HTMD) website
The HTMD website provides guided learning through different aspects of HTMD. These tutorials walk through real-world examples which will help apply the concepts of the course.
Show steps
  • Review the tutorials on the website
  • Select a tutorial to complete
  • Follow the tutorial steps
  • Complete any quizzes or exercises associated with the tutorial
Six other activities
Expand to see all activities and additional details
Show all nine activities
Practice high-throughput screening techniques
Develop proficiency in HTS techniques to enhance your understanding of this key aspect of the course.
Show steps
  • Simulate HTS experiments using software or online tools.
  • Analyze real-world HTS data to identify patterns and trends.
Participate in a study group focused on HTMD
This course is technical and understanding is enhanced through peer engagement. Participating in a dedicated group will amplify the learning outcomes and experience.
Show steps
  • Find a study group to join or start your own
  • Meet regularly with your study group
  • Discuss HTMD concepts and problems
  • Work together on HTMD projects
Practice HTS techniques
High-Throughput Screening is a fundamental technique for HTMD. Practice will help cement the understanding of this process and allow the student to expand their skillset and proficiency in a very sought after area.
Show steps
  • Identify a materials property of interest
  • Select an appropriate HTS method for the property measurement
  • Design and execute an HTS experiment
  • Analyze the HTS data and draw conclusions
Design and conduct a small-scale HTS experiment
Gain hands-on experience with HTS by designing and carrying out your own experiment.
Browse courses on Materials Design
Show steps
  • Define the research question and identify suitable materials.
  • Design and optimize the HTS experiment.
  • Collect and analyze data to draw conclusions.
Create a poster presenting the findings of an HTMD workflow
Developing a poster will demonstrate an understanding of all the steps required in the HTMD workflow. Then presenting the workflow will help the learning solidify and allow for peer engagement.
Show steps
  • Select a specific materials development or characterization problem to focus on
  • Design an HTMD workflow to address the problem
  • Execute the workflow and collect data
  • Analyze the data and draw conclusions
  • Create a poster that presents your findings
Contribute to an open-source HTMD project
Getting involved with an open-source community is a fantastic way to solidify the knowledge and skills required for HTMD. This will immerse the learner in the field.
Show steps
  • Find an open-source HTMD project to contribute to
  • Join the project community
  • Identify a way to contribute to the project
  • Make your contribution to the project

Career center

Learners who complete Introduction to High-Throughput Materials Development will develop knowledge and skills that may be useful to these careers:
Materials Scientist
A Materials Scientist is responsible for designing and developing new materials, as well as studying the structure and properties of existing materials. This course would be extremely helpful for a Materials Scientist, as it would provide them with a deep understanding of the latest techniques in high-throughput materials development.
Materials Engineer
A Materials Engineer is responsible for the design, development, and testing of materials used in a wide variety of industries. This course would be very helpful for a Materials Engineer, as it would provide them with a strong foundation in the latest techniques in high-throughput materials development.
Chemical Engineer
A Chemical Engineer is responsible for the design, development, and operation of chemical plants and processes. This course may be helpful for a Chemical Engineer, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Mechanical Engineer
A Mechanical Engineer is responsible for the design, development, and testing of mechanical systems. This course may be helpful for a Mechanical Engineer, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Electrical Engineer
An Electrical Engineer is responsible for the design, development, and testing of electrical systems. This course may be helpful for an Electrical Engineer, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Biomedical Engineer
A Biomedical Engineer is responsible for the design, development, and testing of medical devices and equipment. This course may be helpful for a Biomedical Engineer, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Industrial Engineer
An Industrial Engineer is responsible for the design, development, and implementation of production systems. This course may be helpful for an Industrial Engineer, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Composite Scientist
A Composite Scientist is responsible for the study of the structure and properties of composites. This course may be helpful for a Composite Scientist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Polymer Scientist
A Polymer Scientist is responsible for the study of the structure and properties of polymers. This course may be helpful for a Polymer Scientist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Metallurgist
A Metallurgist is responsible for the study of the structure and properties of metals. This course may be helpful for a Metallurgist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Ceramist
A Ceramist is responsible for the study of the structure and properties of ceramics. This course may be helpful for a Ceramist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Nanotechnologist
A Nanotechnologist is responsible for the study of the structure and properties of materials at the nanoscale. This course may be helpful for a Nanotechnologist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Materials Characterization Scientist
A Materials Characterization Scientist is responsible for the development and use of techniques to characterize the structure and properties of materials. This course may be helpful for a Materials Characterization Scientist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Physical Chemist
A Physical Chemist is responsible for the study of the physical properties of matter. This course may be helpful for a Physical Chemist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.
Theoretical Physicist
A Theoretical Physicist is responsible for the development of mathematical models to describe the behavior of physical systems. This course may be helpful for a Theoretical Physicist, as it would provide them with some knowledge of the latest techniques in high-throughput materials development.

Reading list

We've selected six books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Introduction to High-Throughput Materials Development.
Provides an introduction to the computational methods used in materials science. It covers topics such as density functional theory, molecular dynamics, and Monte Carlo simulations.
This handbook provides a comprehensive overview of the properties and selection of ferrous materials. It covers topics such as the composition, microstructure, and properties of ferrous materials, as well as the selection of ferrous materials for specific applications.
Provides a comprehensive overview of the science and engineering of ceramic materials. It covers topics such as the structure of ceramics, the properties of ceramics, and the applications of ceramics.
Provides a comprehensive overview of the science and technology of polymers. It covers topics such as the structure of polymers, the properties of polymers, and the applications of polymers.

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