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Vicki Ellingrod
The first phase of translational research — known as “T1” — is the process of moving foundational scientific discoveries into possible approaches for real-world health applications. This course focuses on innovations in basic science discovery, including drug discovery and repurposing and animal studies, that lead to new methods of diagnosis, treatment, and prevention in highly controlled settings. You’ll also discuss the role of the federal government to support and regulate translational research as it moves from basic science to human interventions.
Read more
The first phase of translational research — known as “T1” — is the process of moving foundational scientific discoveries into possible approaches for real-world health applications. This course focuses on innovations in basic science discovery, including drug discovery and repurposing and animal studies, that lead to new methods of diagnosis, treatment, and prevention in highly controlled settings. You’ll also discuss the role of the federal government to support and regulate translational research as it moves from basic science to human interventions.
Read more
The first phase of translational research — known as “T1” — is the process of moving foundational scientific discoveries into possible approaches for real-world health applications. This course focuses on innovations in basic science discovery, including drug discovery and repurposing and animal studies, that lead to new methods of diagnosis, treatment, and prevention in highly controlled settings. You’ll also discuss the role of the federal government to support and regulate translational research as it moves from basic science to human interventions.
This is the second course of five in the “Translational Science” series.
Register for this course and see more details by visiting:
OpenCourser.com/course/klc04k/translating
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What's inside
Syllabus
Week 1
Welcome to Week 1 of Translating Basic Research into Research for Humans. This week you will learn how to 1) identify key differences between basic science research and clinical research, and 2) describe the role of animals in the research process.
Read more
Syllabus
Week 1
Welcome to Week 1 of Translating Basic Research into Research for Humans. This week you will learn how to 1) identify key differences between basic science research and clinical research, and 2) describe the role of animals in the research process.
Read more
Week 2
Welcome to Week 2 of Translating Basic Research into Research for Humans. This week you will learn how to 1) describe potential career paths for basic science researchers, 2) identify team roles for research conducted in the T1 stage of translational science, and 3) describe the types of career development awards available for translational research education.
Week 3
Welcome to Week 3 of Translating Basic Research into Research for Humans. This week you will learn how to 1) explain the process of translating the outcomes of basic science research into improvements in human health, and 2) explain how T1 research is associated with T2 and T3/T4 research.
Good to know
Good to know
Know what's good ,
what to watch for , and
possible dealbreakers
Takes a standard approach to teaching drug discovery and repurposing
Well-structured and easy to follow
Taught by instructors with extensive experience in translational research
Provides a strong foundation for researchers interested in drug discovery and development
Requires a background in basic science research
May not be suitable for learners with no prior experience in research
Save this course
Save Translating Basic Research into Research for Humans to your list so you can find it easily later:
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Activities
Be better prepared
before
your course. Deepen your understanding
during
and
after
it. Supplement your coursework and achieve mastery of the topics covered
in Translating Basic Research into Research for Humans with these
activities:
Familiarize yourself with research methodology
Show steps
Refresh your knowledge of research methodology to strengthen your foundation for translational research.
Browse courses on
Research Methodology
Show steps
-
Review your lecture notes and textbooks from previous courses.
-
Identify key concepts and theories of research methodology.
-
Complete practice problems or exercises to reinforce your understanding.
Review course preview materials
Show steps
Review the introduction materials provided in the course review key ideas and course expectations.
Show steps
Explore online resources on translational research
Show steps
Supplement your understanding of translational research by exploring reputable online resources.
Browse courses on
Translational Research
Show steps
-
Identify reputable websites, such as NIH or WHO.
-
Search for articles, videos, or webinars on translational research.
-
Take notes or summarize the key points you learn.
13 other activities
Expand to see all activities and additional details
Show all 16 activities
Participate in pre-course webinars
Show steps
Attend any pre-course webinars offered to become familiar with the course content and instructors.
Show steps
-
Review webinar schedule and registration materials.
-
Attend the webinar and take notes.
Organize a Study Group with Classmates
Show steps
Forming a study group will provide you with opportunities to discuss course material, reinforce concepts, and quiz each other, all promoting better understanding and retention.
Show steps
-
Identify a group of classmates who are interested in collaborating.
-
Decide on a regular meeting time and location.
-
Prepare discussion questions and topics to guide your study sessions.
Start a research project on a specific topic in translational science.
Show steps
Initiate a research project to apply the concepts learned in this course and gain hands-on experience in translational science.
Show steps
-
Identify a research topic of interest within the field of translational science.
-
Develop a research plan outlining your research question, methodology, and expected outcomes.
-
Collect and analyze data relevant to your research topic.
-
Write a research report summarizing your findings and discussing their implications for translational science.
Practice identifying potential career paths
Show steps
Gain a better understanding of the diverse career options available in translational research.
Browse courses on
Career Paths
Show steps
-
Research different job titles and descriptions.
-
Identify the skills and qualifications required for each role.
-
Consider your interests and career goals.
-
Develop a plan to pursue your desired career path.
Practice Solving Problems in Translational Science
Show steps
Regularly practicing problem-solving will strengthen your understanding of the principles and applications of translational science.
Show steps
-
Review course materials and identify key concepts related to translational science.
-
Find practice problems online or in textbooks and attempt to solve them independently.
-
Check your solutions and identify areas where you need further clarification.
Engage in discussions with classmates
Show steps
Enhance your understanding by exchanging ideas and insights with your peers.
Show steps
-
Attend live or virtual class discussions.
-
Participate actively by asking questions and sharing your perspectives.
-
Collaborate on group projects or assignments.
Create an Infographic on the Role of Animal Studies in Translational Research
Show steps
Creating an infographic will allow you to synthesize information and visually represent the importance of animal studies in translational research, deepening your understanding of the topic.
Show steps
-
Gather information from course materials and reputable sources on the role of animal studies in translational research.
-
Use a design platform to create a visually appealing and informative infographic.
-
Share your infographic with classmates or online communities to educate others about the topic.
Attend a Workshop on Animal Studies in Translational Research
Show steps
This workshop will provide you with hands-on experience in designing and conducting animal studies, a crucial aspect of translational research.
Show steps
-
Register for the workshop and attend all sessions.
-
Actively participate in discussions and ask questions to clarify concepts.
-
Apply the techniques learned during the workshop to your own research projects.
Volunteer at a Research Lab Focused on Translational Medicine
Show steps
Volunteering in a research lab will provide you with hands-on experience and exposure to the practical aspects of translational medicine, complementing your theoretical knowledge.
Show steps
-
Research local research labs involved in translational medicine.
-
Contact the labs and inquire about volunteer opportunities.
-
Attend volunteer training and orientation sessions.
Participate in a Hackathon Focused on Translational Medicine
Show steps
Engaging in a hackathon will challenge you to apply your knowledge of translational research in a practical and collaborative setting.
Show steps
-
Find and register for a hackathon relevant to translational medicine.
-
Form a team or work independently on a project that addresses a specific translational medicine challenge.
-
Develop a solution and prepare a presentation to showcase your work.
Develop a detailed research proposal
Show steps
Solidify your understanding by outlining a comprehensive research proposal in translational research.
Browse courses on
Research Proposal
Show steps
-
Define the research question and objectives.
-
Review relevant literature and identify gaps in knowledge.
-
Develop a research design and methodology.
-
Anticipate potential challenges and plan for mitigation.
-
Prepare a clear and concise budget plan.
Develop a Grant Proposal for a Translational Research Project
Show steps
Writing a grant proposal will require you to thoroughly research a specific translational research topic, develop a research plan, and present it in a convincing manner, enhancing your understanding of the research process.
Show steps
-
Identify a specific research question or problem in translational medicine.
-
Conduct a comprehensive literature review to support your proposed research.
-
Develop a detailed research plan, including methodology, timeline, and expected outcomes.
Attend industry conferences or webinars
Show steps
Expand your network and gain insights from experts in the field of translational research.
Show steps
-
Identify relevant industry conferences or webinars.
-
Register and attend the events.
-
Engage with speakers and attendees.
-
Follow up with potential mentors or collaborators.
Familiarize yourself with research methodology
Show steps
Refresh your knowledge of research methodology to strengthen your foundation for translational research.
Browse courses on
Research Methodology
Show steps
Show steps
Show steps
- Review your lecture notes and textbooks from previous courses.
- Identify key concepts and theories of research methodology.
- Complete practice problems or exercises to reinforce your understanding.
Review course preview materials
Show steps
Review the introduction materials provided in the course review key ideas and course expectations.
Show steps
Show steps
Show steps
Explore online resources on translational research
Show steps
Supplement your understanding of translational research by exploring reputable online resources.
Browse courses on
Translational Research
Show steps
Show steps
Show steps
- Identify reputable websites, such as NIH or WHO.
- Search for articles, videos, or webinars on translational research.
- Take notes or summarize the key points you learn.
13 other activities
Expand to see all activities and additional details
Show all 16 activities
Participate in pre-course webinars
Show steps
Attend any pre-course webinars offered to become familiar with the course content and instructors.
Show steps
Show steps
Show steps
- Review webinar schedule and registration materials.
- Attend the webinar and take notes.
Organize a Study Group with Classmates
Show steps
Forming a study group will provide you with opportunities to discuss course material, reinforce concepts, and quiz each other, all promoting better understanding and retention.
Show steps
Show steps
Show steps
- Identify a group of classmates who are interested in collaborating.
- Decide on a regular meeting time and location.
- Prepare discussion questions and topics to guide your study sessions.
Start a research project on a specific topic in translational science.
Show steps
Initiate a research project to apply the concepts learned in this course and gain hands-on experience in translational science.
Show steps
Show steps
Show steps
- Identify a research topic of interest within the field of translational science.
- Develop a research plan outlining your research question, methodology, and expected outcomes.
- Collect and analyze data relevant to your research topic.
- Write a research report summarizing your findings and discussing their implications for translational science.
Practice identifying potential career paths
Show steps
Gain a better understanding of the diverse career options available in translational research.
Browse courses on
Career Paths
Show steps
Show steps
Show steps
- Research different job titles and descriptions.
- Identify the skills and qualifications required for each role.
- Consider your interests and career goals.
- Develop a plan to pursue your desired career path.
Practice Solving Problems in Translational Science
Show steps
Regularly practicing problem-solving will strengthen your understanding of the principles and applications of translational science.
Show steps
Show steps
Show steps
- Review course materials and identify key concepts related to translational science.
- Find practice problems online or in textbooks and attempt to solve them independently.
- Check your solutions and identify areas where you need further clarification.
Engage in discussions with classmates
Show steps
Enhance your understanding by exchanging ideas and insights with your peers.
Show steps
Show steps
Show steps
- Attend live or virtual class discussions.
- Participate actively by asking questions and sharing your perspectives.
- Collaborate on group projects or assignments.
Create an Infographic on the Role of Animal Studies in Translational Research
Show steps
Creating an infographic will allow you to synthesize information and visually represent the importance of animal studies in translational research, deepening your understanding of the topic.
Show steps
Show steps
Show steps
- Gather information from course materials and reputable sources on the role of animal studies in translational research.
- Use a design platform to create a visually appealing and informative infographic.
- Share your infographic with classmates or online communities to educate others about the topic.
Attend a Workshop on Animal Studies in Translational Research
Show steps
This workshop will provide you with hands-on experience in designing and conducting animal studies, a crucial aspect of translational research.
Show steps
Show steps
Show steps
- Register for the workshop and attend all sessions.
- Actively participate in discussions and ask questions to clarify concepts.
- Apply the techniques learned during the workshop to your own research projects.
Volunteer at a Research Lab Focused on Translational Medicine
Show steps
Volunteering in a research lab will provide you with hands-on experience and exposure to the practical aspects of translational medicine, complementing your theoretical knowledge.
Show steps
Show steps
Show steps
- Research local research labs involved in translational medicine.
- Contact the labs and inquire about volunteer opportunities.
- Attend volunteer training and orientation sessions.
Participate in a Hackathon Focused on Translational Medicine
Show steps
Engaging in a hackathon will challenge you to apply your knowledge of translational research in a practical and collaborative setting.
Show steps
Show steps
Show steps
- Find and register for a hackathon relevant to translational medicine.
- Form a team or work independently on a project that addresses a specific translational medicine challenge.
- Develop a solution and prepare a presentation to showcase your work.
Develop a detailed research proposal
Show steps
Solidify your understanding by outlining a comprehensive research proposal in translational research.
Browse courses on
Research Proposal
Show steps
Show steps
Show steps
- Define the research question and objectives.
- Review relevant literature and identify gaps in knowledge.
- Develop a research design and methodology.
- Anticipate potential challenges and plan for mitigation.
- Prepare a clear and concise budget plan.
Develop a Grant Proposal for a Translational Research Project
Show steps
Writing a grant proposal will require you to thoroughly research a specific translational research topic, develop a research plan, and present it in a convincing manner, enhancing your understanding of the research process.
Show steps
Show steps
Show steps
- Identify a specific research question or problem in translational medicine.
- Conduct a comprehensive literature review to support your proposed research.
- Develop a detailed research plan, including methodology, timeline, and expected outcomes.
Attend industry conferences or webinars
Show steps
Expand your network and gain insights from experts in the field of translational research.
Show steps
Show steps
Show steps
- Identify relevant industry conferences or webinars.
- Register and attend the events.
- Engage with speakers and attendees.
- Follow up with potential mentors or collaborators.
Career center
Learners who complete Translating Basic Research into Research for Humans will develop knowledge and skills
that may be useful to these careers:
Biomedical Engineer
Biomedical Engineer
A Biomedical Engineer is just one of many roles in the exciting field of translational research. This course will serve as an excellent foundation for you as you pursue work to translate basic science discoveries into new methods of diagnosis, treatment, and prevention in highly controlled settings. Additionally, you will gain insights into the role of animal studies in the research process. This knowledge will help you excel in this career.
Research Scientist
Research Scientist
Research Scientists contribute to the advancement of scientific knowledge in a variety of fields through designing, conducting, and analyzing research studies. Completing this course will provide insights into the processes of translational research, including animal studies for drug discovery and repurposing.
Research Assistant
Research Assistant
Research Assistants play a crucial role in translational research by assisting scientists with their research projects. This course will provide you with a strong foundation in the principles of translational research, from basic science discovery to clinical trials.
Veterinarian
Veterinarian
Veterinarians play a vital role in translational research by conducting animal studies to evaluate the safety and efficacy of new medications and treatments. This course will provide you with a strong foundation in the principles of translational research, from basic science discovery to clinical trials.
Clinical Research Associate
Clinical Research Associate
Working as a Clinical Research Associate (CRA) will allow you to play an integral role in translating basic research into research for humans. In this position, you will be responsible for managing clinical trials, ensuring that they are conducted safely and ethically, and collecting and analyzing data. Understanding the process of translational research will help you succeed in this role.
Pharmaceutical Sales Representative
Pharmaceutical Sales Representative
Pharmaceutical Sales Representatives play a crucial role in translational research by informing healthcare providers about new medications and treatments. This course will help you understand the different stages of translational research, from basic science discovery to clinical trials, so you can effectively communicate the benefits of new medications to healthcare providers.
Statistician
Statistician
Statisticians apply mathematical and statistical methods to collect, analyze, interpret, and present data. Understanding the process of translational research, from basic science discovery to clinical trials, will help you to apply statistical methods effectively in this field of work.
Regulatory Affairs Specialist
Regulatory Affairs Specialist
A Regulatory Affairs Specialist ensures that medical products are safe and meet all regulatory requirements. Gaining an understanding of the process of translational research will provide you with a strong foundation for this role. Additionally, you will learn about the role of the federal government in supporting and regulating translational research.
Patent Attorney
Patent Attorney
A Patent Attorney focuses on the legal side of inventions. Given that translational research is heavily focused on innovations in basic science discovery and drug discovery, you may wish to consider a career as a patent attorney. This course will provide you with insights that you can use to advise clients on how to protect their intellectual property.
Toxicologist
Toxicologist
Toxicologists are scientists who study the effects of toxic substances on living organisms. This course will provide you with a strong foundation in the principles of translational research, which will help you to design and conduct toxicology studies.
Biostatistician
Biostatistician
A Biostatistician makes use of statistical methods to solve problems in biology, medicine, and public health. A role in this field supports and intersects with translational research as well as roles in the federal government working to support and regulate translational research. Understanding the role of the federal government in the research process will help you excel.
Science Writer
Science Writer
Science Writers translate complex scientific and medical information into easily understandable content for a variety of audiences. Taking this course may be useful as you gain insights into the process of translating basic science discoveries into clinical applications, which you can share with readers through your writing.
Government Relations
Government Relations
Government Relations roles support the public policy and government strategy goals of an organization, from protecting the environment to developing new technologies. This course may be useful to those seeking a role in government relations related to translational research, as it will provide insights into the role of the federal government in supporting and regulating this field.
Medical Writer
Medical Writer
A Medical Writer works to develop content that helps explain complex medical and scientific information to a variety of audiences. This course may be useful as you gain insights into the process of translating basic science discoveries into clinical applications. This understanding will help you create accurate and informative content.
Zoologist
Zoologist
Zoologists study the behavior, physiology, anatomy, and genetics of animals. This course may be helpful to you as you gain insights into the use of animal studies in the drug discovery and repurposing process, as well as other areas of translational research.
For more career information including salaries, visit:
OpenCourser.com/course/klc04k/translating
Reading list
We've selected seven books
that we think will supplement your
learning. Use these to
develop background knowledge, enrich your coursework, and gain a
deeper understanding of the topics covered in
Translating Basic Research into Research for Humans .
Save
Provides a comprehensive overview of clinical trial methodology. It valuable resource for researchers who are designing or conducting clinical trials.
Provides an introduction to biomedical imaging, with a focus on the physical principles and techniques used in medical imaging. It is written by an experienced researcher and educator in the field.
This textbook is designed for medical students and provides a comprehensive overview of pharmacology. It covers all aspects of the field, from the basic principles of drug action to the clinical use of drugs.
Provides a comprehensive overview of clinical epidemiology, with a focus on the basic principles of the field. It is written by two experienced researchers who share their insights on the use of epidemiology in clinical medicine.
Covers the practical aspects of conducting clinical research, including study design, data collection, and data analysis. It useful reference for researchers who are new to clinical research or who want to improve their skills.
Provides guidance on the development and use of clinical practice guidelines. It is written by a committee of experts from the Institute of Medicine.
This report from the National Research Council examines the role of the federal government in translational research.
For more information about how these books relate to this course, visit:
OpenCourser.com/course/klc04k/translating
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Qualitative Research Methods
Level
Introductory
Via
Coursera
Institution
University of Michigan
Instructor
Vicki Ellingrod
Language
English
This course belongs to a
collection
called
Translational Science . It's comprised of four courses:
- Translating Research to Communities
- Translating Basic Research into Research for Humans (viewing)
- Translating Research to Patients
- Translating Research to Healthcare Policy
Good to know
Takes a standard approach to teaching drug discovery and repurposing
Well-structured and easy to follow
Taught by instructors with extensive experience in translational research
Provides a strong foundation for researchers interested in drug discovery and development
Requires a background in basic science research
May not be suitable for learners with no prior experience in research
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