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Vicki Ellingrod

The second phase of translational research — known as “T2” — assesses the value of applying discoveries to clinical practice, which leads to the development of evidence-based guidelines. This course focuses on clinical trials, the value of applying discoveries to clinical practice, and best practices for conducting research. You’ll see examples of human subjects research through clinical trials that have been translated into practice and, later, into basic scientific discoveries. You’ll also discuss the role of the federal government in supporting and regulating translational research conducted on humans.

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The second phase of translational research — known as “T2” — assesses the value of applying discoveries to clinical practice, which leads to the development of evidence-based guidelines. This course focuses on clinical trials, the value of applying discoveries to clinical practice, and best practices for conducting research. You’ll see examples of human subjects research through clinical trials that have been translated into practice and, later, into basic scientific discoveries. You’ll also discuss the role of the federal government in supporting and regulating translational research conducted on humans.

This is the third course of five in the “Translational Science” series.

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What's inside

Syllabus

Week 1
Welcome to Week 1 of Translating Research to Patients. This week you will learn to 1) describe the four types of clinical trials research and the purpose for each type, and 2) define human subjects research and describe its purpose in the ethical conduct of translational research.
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Week 2
Welcome to Week 2 of Translating Research to Patients. This week you will learn to 1) explain the role of the IRB in the ethical conduct of research, and 2) describe the role of the US Federal Drug Administration in the development and testing of pharmaceutical therapies.
Week 3
Welcome to Week 3 of Translating Research to Patients. This week you will learn to 1) describe examples of human subjects research and identify where it fits in the translational research spectrum, and 2) review your Individualized Development Plan (IDP) and update it as needed.

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Teaches the importance of clinical research, its variety and use in real-world applications
Emphasis on evidence-based guidelines helps learners understand how research impacts clinical practice
Focuses on best practices for conducting research, providing valuable insights for aspiring researchers
Provides examples of how research has successfully translated into practice, demonstrating its real-world impact
Covers the role of the federal government in supporting and regulating research on humans, ensuring ethical and responsible practices
Suitable for individuals involved in clinical research, healthcare professionals, and those interested in translational science

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Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Translating Research to Patients with these activities:
Review and Refresh Principles of Translational Research
Refreshes foundational understanding of translational research principles, preparing for course content
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  • Review syllabus and course overview to identify key concepts
  • Revisit previous notes, textbooks, or online resources on translational research
Review Basic Statistical Concepts
Revisiting foundational concepts will strengthen your ability to understand more complex topics later in the course.
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  • Review probability distributions
  • Do some practice problems on hypothesis testing
Join a Study Group
Engaging with peers will enhance your understanding and provide different perspectives.
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  • Identify potential study partners
  • Establish a regular meeting schedule
  • Share notes and discuss course materials
Nine other activities
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Explore Case Studies in Clinical Trials
Enhances understanding of clinical trial design and outcomes through guided tutorials
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  • Identify credible sources for case studies in clinical trials
  • Analyze and summarize key findings and implications of case studies
Practice Clinical Trial Design
Regular practice will improve your understanding and ability to design clinical trials.
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  • Identify the research question
  • Define the study population and interventions
  • Choose appropriate outcome measures
  • Develop a data collection plan
Engage in Peer Discussions on Research Applications
Fosters critical thinking and knowledge sharing through peer discussions on practical applications of research
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  • Join or create study groups with peers
  • Engage in regular discussions on assigned topics or research articles
Create a data visualization
Creating a data visualization will allow you to gain practical experience and deepen your understanding.
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  • Choose a dataset
  • Clean and prepare the data
  • Select appropriate visualizations
  • Create and refine the visualization
Connect with Experts in Translational Research
Provides access to guidance and insights from experienced professionals
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  • Identify potential mentors in the field of translational research
  • Reach out and schedule informational interviews or meetings
Attend a Workshop on Clinical Trial Management
Attending industry workshops will supplement your learning and provide valuable networking opportunities.
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  • Research and identify relevant workshops
  • Register for a workshop
  • Participate actively in the workshop
Develop a Research Poster or Presentation
Encourages synthesis and effective communication of research findings
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Show steps
  • Identify a research topic of interest within the course content
  • Gather and analyze data
  • Create a clear and visually appealing poster or presentation
Explore Emerging Trends in Translational Research
Staying up-to-date with current trends will broaden your knowledge and improve your understanding of the field.
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  • Identify reputable sources of information
  • Attend webinars or online conferences
  • Review recent scientific articles
Volunteer at a Clinical Research Center
Getting practical experience will reinforce your theoretical knowledge and enhance your future job prospects.
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  • Identify relevant research centers
  • Contact the centers and inquire about volunteer opportunities
  • Attend training and orientation

Career center

Learners who complete Translating Research to Patients will develop knowledge and skills that may be useful to these careers:
Registered Nurse
If you want to be a Registered Nurse, you'll need to have a robust understanding of translational research. This is because translational research takes research and applies it to clinical practice. The application of this research is done in part by Registered Nurses. This course will teach you how to assess the value of applying research to clinical practice, how to conduct a pharmaceutical clinical trial, and best practices for conducting research. It will also discuss the role of the federal government in supporting translational research.
Genetic Counselor
Many Genetic Counselors work in translational research, helping to apply new genetic discoveries to improve patient care. This course will introduce you to the four types of clinical trials and how to define human subjects research, which is essential for Genetic Counselors to understand. You'll also learn how to explain the role of the IRB in the ethical conduct of research, and the role of the US Federal Drug Administration in the development and testing of pharmaceutical therapies. This knowledge will build a foundation for you as a Genetic Counselor and help you succeed in the field.
Biostatistician
Biostatisticians are responsible for the design, analysis, and interpretation of data in clinical trials. This course will teach you the value of applying discoveries to clinical practice, and best practices for conducting research, which are crucial skills for Biostatisticians. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will be highly relevant to your work as a Biostatistician.
Healthcare Administrator
Healthcare Administrators oversee the day-to-day operations of healthcare facilities, making decisions that impact patient care. This course will teach you how to assess the value of applying discoveries to clinical practice, and best practices for conducting research, which are both essential for Healthcare Administrators. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will help you make informed decisions in your role.
Clinical Research Associate
Clinical Research Associates work with patients and healthcare providers to ensure that clinical trials are conducted safely and ethically. This course will help you build a foundation in clinical trials, including the four types of clinical trials and how to define human subjects research. You'll also learn about the role of the IRB in the ethical conduct of research and the role of the US Federal Drug Administration in the development and testing of pharmaceutical therapies, which are both critical areas of knowledge for Clinical Research Associates.
Medical Writer
Medical Writers translate complex medical information into easy-to-understand language for patients and the public. This course will teach you how to assess the value of applying discoveries to clinical practice, and best practices for conducting research, which will help you write accurate and engaging medical content. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will provide you with a broader understanding of the medical field.
Pharmaceutical Sales Representative
Pharmaceutical Sales Representatives sell and market drugs and medical devices to healthcare providers. This course will teach you about the value of applying discoveries to clinical practice, and best practices for conducting research, which will give you a better understanding of the products you're selling. You'll also learn about the role of the US Federal Drug Administration in the development and testing of pharmaceutical therapies, which is essential knowledge for Pharmaceutical Sales Representatives.
Postdoctoral Researcher
Postdoctoral Researchers conduct research in a specific field of study. This course will help you build a foundation in translational research, and best practices for conducting research, which are both essential for Postdoctoral Researchers. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will help you understand the broader context of your research.
Science Writer
Science Writers communicate complex scientific information to the public. This course will teach you how to assess the value of applying discoveries to clinical practice, and best practices for conducting research, which will help you write accurate and engaging science articles. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will give you a broader understanding of the scientific field.
Epidemiologist
Epidemiologists investigate the causes of disease and other health problems in populations. This course will teach you how to assess the value of applying discoveries to clinical practice, and best practices for conducting research, which are both essential for Epidemiologists. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will help you understand the broader context of your work.
Clinical Trial Manager
Clinical Trial Managers oversee the day-to-day operations of clinical trials. This course will help you build a foundation in clinical trials, including the four types of clinical trials and how to define human subjects research. You'll also learn about the role of the IRB in the ethical conduct of research and the role of the US Federal Drug Administration in the development and testing of pharmaceutical therapies, which are all critical areas of knowledge for Clinical Trial Managers.
Physician
Physicians provide medical care to patients. This course will teach you how to assess the value of applying discoveries to clinical practice, and best practices for conducting research, which are both essential for Physicians. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will help you stay up-to-date on the latest medical advances.
Pharmacist
Pharmacists dispense medications and provide advice on their use. This course will teach you about the value of applying discoveries to clinical practice, and best practices for conducting research, which will help you stay up-to-date on the latest medications and treatments. You'll also learn about the role of the US Federal Drug Administration in the development and testing of pharmaceutical therapies, which is essential knowledge for Pharmacists.
Health Policy Analyst
Health Policy Analysts research and analyze health care policies. This course will help build a foundation in translating research to patients, and best practices for conducting research, which are both essential for Health Policy Analysts. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will help you understand the broader context of your work.
Research Scientist
Research Scientists conduct research in a specific field of study. This course will teach you how to assess the value of applying discoveries to clinical practice, and best practices for conducting research, which are both essential for Research Scientists. You'll also learn about the role of the federal government in supporting and regulating translational research conducted on humans, which will help you understand the broader context of your research.

Reading list

We've selected seven books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Translating Research to Patients.
The Belmont Report is an influential document that outlines the ethical principles that should guide the conduct of research involving human subjects. It is essential reading for anyone interested in the ethical conduct of research.
This report provides an overview of the ethical and legal issues that arise in the conduct of clinical research.
Biostatistics comprehensive textbook that provides a solid foundation in biostatistics for students and professionals in the health sciences, with a focus on the applications of statistics to clinical research.
This textbook is designed to provide a clear and concise introduction to medical statistics, with a focus on clinical trials, data analysis, and evidence-based medicine.
This textbook provides a concise introduction to the principles of clinical epidemiology.

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