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Design and Interpretation of Clinical Trials

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people.

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Rating 4.7 based on 301 ratings
Length 7 weeks
Starts Jul 10 (41 weeks ago)
Cost $49
From Johns Hopkins University via Coursera
Instructors Janet Holbrook, PhD, MPH, Lea T. Drye, PhD
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Medicine And Healthcare Clinical Science Research

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What people are saying

clinical research

I strongly recommend for whom interest in clinical research.

I recommend it for all graduate students and people involved in clinical research.

Extremely useful for scholars and post-grad students, or really, anyone who is interested to work in the field of Clinical Research.

I am a new clinical research coordinator nurse and I took this course to gain knowledge about the studies I am coordinating so I am more familiar with the design of studies I am in and so I can be more efficient wonderful course Great course, easy to understand.

I develop clinical research (through registries and data collection in cardiac emergencies) in a small hospital in Brazil.

Intresting and informative course for design of clini A rare course in clinical trials, and also a good one.Strongly recommend for those interested in clinical research!

It is very fortunate to learn from such expertise in clinical research through this course.

A great course for people working in the Clinical Research industry!

el curso es excelente It was amagazin An amazing course especially for professionals who work in clinical research operations.

I hope to learn more about clinical trials great course Excellent course for me, as I'm a pharmacist, I'm working in clinical research area and I was looking for acquiring more knoledges and reinforme my previous knowledges regarding clinical trials, I'm gonna llok for more courses regarding clinical trials.

Great course for people in clinical research field.

The course gave me the exposure to CONSORT guidelines, different types of study designs which is very helpful for my Clinical Research profession.Thanks for me personally the level was to basic.

very interesting course , but need to be shorter and more practical When I started this course, I had no idea how important it is for me to understand what goes on in the background of clinical research and how important are the ethical considerations.

Now, I think I have started developing a sense of clinical research.

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interpretation of clinical trials

It's a very good course to learn basic information about design and interpretation of clinical trials; however, it would be much useful if it included more details about the studies designs and outcome analysing.

This course gives a excellent overview of design and interpretation of clinical trials.

I'm very pleased with the design and interpretation of clinical trials course.

it was very good class Wonderful Its a great course I loved it This course is very interesting and I learn a lot about Design and Interpretation of clinical Trials Excellent beginner course on design and interpretation of clinical trials, complements a lot of what I reviewed on my classes and I would like to take a more advanced course on the topic.

A fantastic foundational course that covers all the essentials to understand and appreciate the design and interpretation of clinical trials.

Excellent training to get a good understanding of Design and Interpretation of Clinical Trials very well organised, easy to follow by watching videos along with their transcript so I could compliment images and summary slides with detailed explanations of teacher.You can also re-schedule the timelines as it better suits you.

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design and interpretation

It is an excellent starter for students wishing to pursue clinical research studies as it presents the important first steps for the design and interpretation of clinical trial research.

Very good course contains all the materials and excellent material Great starting point, offers fundamental knowledge on clinical trials design and interpretation, gets you familiar with the terminology and arouses interest for more information on this very interesting and exciting topic.

very good course

Very good course!

Informative and basic knowledge about clinical trials Very good course.

great course to refresh my knowledge and update some concepts Very good course.

A very good course: useful information explained in a clear and simple way.

This is a very good course to form a broad knowledge in clinical trial design This is a great course!

Very good course.

Very good course, I have post-diploma in Clinical Trials Management, but this course was a good reminder of what I've learnt so far.

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very informative

However, I feel, it shall also incorporate issues like protocol designing, case record form designing, sample size calculations It's very informative , with lots of essential info.

Very informative course for the beginners the quiz questions can be more in-depth The knowledge you'll learn and obtain in this course is rich and very helpful.

Very informative!

great course Very informative with lots of reading material, very knowledgeable faculties, thank you!

very informative course.

A very informative and interesting course.

It was very informative and easy to access, follow and complete course :) Very helpful Excelente capacitación, contenido y formación.Recomendado en un 100% Very good experience and thorough detailed explanation of clinical trails!!

it was a really good and informative course , however I a struggling to retrieve my certificateAlternative email- [email protected] Very informative course!

Very informative and organized lectures.

The best thing is a concise but precise information that is very student friendly very informative online course for those who working in Clinical Research Field veryusefullfortheknowledgepurpurseaswellasmakeagrowthInprofessIonalcarrier excellent if you are begining at the clinical trials world, or if you want to complement your knowledge

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easy to follow

nice course .. excellent lecturer ... thanks very much i advice it for every one work in drug field especially in R&D department Explanations are complicated Very easy to follow, concise yet informative.Thank you and well done.

The lectures are easy to follow.

I thought the lectures were very well designed and easy to follow.

My only regret : I'd have liked to hear more about NI and equivalence trials very easy to follow and super useful in real life.

It was easy to follow lectures, gained much of knowledge, especially liked case studies of RCT and o Learned a lot!

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knowledge about

It is pretty exciting course with rich knowledge in clinical trials' field which is well expressed with practical examples This course really helped me to understand trials and gave me starting knowledge about how to design a trial.

I improved my knowledge about this argument.

This course provides me with valuable new knowledge about clinical trials.

Great class, Janet in particular is fun to listen to and you can really hear her dedication to the cause of making knowledge about clinical trials more broadly available.

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highly recommend

I would highly recommend this anyone looking for the knowledge in clinical trial.

I highly recommend it!

I would highly recommend it for any student or professional in health care - being you directly involved with research or not.

An eye opener - highly recommend.

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trial designs

This course has certainly provided the essential knowledge about clinical trial designs,Moreover the lectures are of optimal length and does not burden you,The way the course is designed and taught is excellent, This is good course, which provides very basic and fundamental of clinical trials.

Excellent primer on the types of trial designs and how to interpret study results and reports.

Having said that, it gives a good overview on clinical trial designs.

i got to understand the various clinical trial designs used as well as the rationale behind using such designs to conduct clinical trials.

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for people

Thanks to coursera for launching a course like this for people like me who cannot afford a regular or dedicated time due to professional commitments.

It is very useful for people starting to approach this field of studies.

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Careers

An overview of related careers and their average salaries in the US. Bars indicate income percentile.

Clinical Trials Coordinator Nurse $50k

Clinical Trials Coordinator 3 $52k

Clinical trials manufacturing technician $58k

Clinical Trials Administrator 2 $64k

Clinical Trials Specialist 3 $67k

Oncology Clinical Trials Nurse $69k

Clinical Trials Coordinator Consultant $75k

Clinical Trials Management $75k

Clinical Trials Statistician $76k

US Clinical Trials Coordinator $78k

CLINICAL TRIALS COORD B $78k

Clinical Trials Finance $120k

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Rating 4.7 based on 301 ratings
Length 7 weeks
Starts Jul 10 (41 weeks ago)
Cost $49
From Johns Hopkins University via Coursera
Instructors Janet Holbrook, PhD, MPH, Lea T. Drye, PhD
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Medicine And Healthcare Clinical Science Research

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