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Do you want to enter the field of Bioinformatics, but don't know enough about
Are you curious about the recent advances in DNA sequencing technology, and how it can be applied to Personalized Cancer Therapy and Disease Research?
Read more
Do you want to enter the field of Bioinformatics, but don't know enough about
Are you curious about the recent advances in DNA sequencing technology, and how it can be applied to Personalized Cancer Therapy and Disease Research?
Read more
Do you want to enter the field of Bioinformatics, but don't know enough about
Are you curious about the recent advances in DNA sequencing technology, and how it can be applied to Personalized Cancer Therapy and Disease Research?
Do you want to use Bioinformatics tools to analyze data generated by Next Generation Sequencing?
By the end of this course:
You will have a strong foundation in It covers Biology prerequisites and quality control. Future courses will cover data analysis in more detail.
Project:
This course includes a step-by-step guided project.
This project will assess the quality of raw data from an Illumina sequencer.
You will then use FastQC and Trimmomatic to improve the quality of this data.
Prerequisites:
Biology and Chemistry at high school 10th grade level
Elementary Statistics such as interpreting charts, histograms, and box-and-whisker plots
You must enjoy Biology
This is an introductory course ideal for those with no prior experience in Next Generation Sequencing Analysis.
Enroll today, and launch your career in Bioinformatics.
Register for this course and see more details by visiting:
OpenCourser.com/course/vh9t24/genetics
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possible dealbreakers
Suitable for beginners seeking an introduction to Next Generation Sequencing Analysis
Provides a foundation in Biology prerequisites and quality control
Includes a step-by-step guided project for assessing and improving Illumina sequencing data quality
Assumes basic Biology and Chemistry knowledge at a high school level
Lacks coverage of advanced data analysis techniques
Save this course
Save Genetics and Next Generation Sequencing for Bioinformatics to your list so you can find it easily later:
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Activities
Be better prepared
before
your course. Deepen your understanding
during
and
after
it. Supplement your coursework and achieve mastery of the topics covered
in Genetics and Next Generation Sequencing for Bioinformatics with these
activities:
Review Biology and Chemistry
Show steps
Refresh high school Biology and Chemistry knowledge to strengthen understanding of key concepts covered in the course.
Browse courses on
Biology
Show steps
-
Review biology textbooks, focusing on cells, DNA, and genetics
-
Review chemistry textbooks, focusing on basics of molecular and biochemistry
-
Complete practice problems and exercises related to these topics
Join a Bioinformatics Discussion Forum
Show steps
Engage with peers and experts in bioinformatics to clarify concepts and learn from others' experiences.
Show steps
-
Identify and join active online discussion forums or communities focused on bioinformatics
-
Participate in discussions by asking questions, sharing insights, and engaging with others
-
Seek feedback and support from the community on course-related topics
Practice Quality Control Techniques
Show steps
Reinforce understanding of quality control techniques by practicing on sample NGS data.
Browse courses on
Quality Control
Show steps
-
Obtain sample NGS data from repositories or online resources
-
Use software like FastQC or Trimmomatic to assess and improve data quality
-
Compare results with expected quality metrics and identify areas for improvement
Three other activities
Expand to see all activities and additional details
Show all six activities
Explore Advanced NGS Analysis Tools
Show steps
Expand knowledge of bioinformatics tools by exploring advanced NGS analysis techniques.
Show steps
-
Identify specific analysis techniques of interest, such as variant calling or gene expression analysis
-
Find and follow tutorials or online courses that cover these techniques
-
Apply the learned techniques to sample NGS data
Mentor Junior Students
Show steps
Reinforce understanding of course concepts by explaining them to others and providing guidance to junior students.
Show steps
-
Identify opportunities to mentor junior students in bioinformatics or related fields
-
Provide guidance on course content, research projects, or career development
-
Review and provide feedback on their work, offering constructive criticism and encouragement
Develop a Bioinformatic Pipeline
Show steps
Deepen understanding of bioinformatics tools and workflows by creating a custom pipeline for NGS data analysis.
Show steps
-
Identify the specific analysis tasks to be included in the pipeline
-
Select and integrate appropriate bioinformatics tools for each task
-
Develop a workflow that automates the execution of these tools
-
Test and validate the pipeline using sample data
Review Biology and Chemistry
Show steps
Refresh high school Biology and Chemistry knowledge to strengthen understanding of key concepts covered in the course.
Browse courses on
Biology
Show steps
Show steps
Show steps
- Review biology textbooks, focusing on cells, DNA, and genetics
- Review chemistry textbooks, focusing on basics of molecular and biochemistry
- Complete practice problems and exercises related to these topics
Join a Bioinformatics Discussion Forum
Show steps
Engage with peers and experts in bioinformatics to clarify concepts and learn from others' experiences.
Show steps
Show steps
Show steps
- Identify and join active online discussion forums or communities focused on bioinformatics
- Participate in discussions by asking questions, sharing insights, and engaging with others
- Seek feedback and support from the community on course-related topics
Practice Quality Control Techniques
Show steps
Reinforce understanding of quality control techniques by practicing on sample NGS data.
Browse courses on
Quality Control
Show steps
Show steps
Show steps
- Obtain sample NGS data from repositories or online resources
- Use software like FastQC or Trimmomatic to assess and improve data quality
- Compare results with expected quality metrics and identify areas for improvement
Three other activities
Expand to see all activities and additional details
Show all six activities
Explore Advanced NGS Analysis Tools
Show steps
Expand knowledge of bioinformatics tools by exploring advanced NGS analysis techniques.
Show steps
Show steps
Show steps
- Identify specific analysis techniques of interest, such as variant calling or gene expression analysis
- Find and follow tutorials or online courses that cover these techniques
- Apply the learned techniques to sample NGS data
Mentor Junior Students
Show steps
Reinforce understanding of course concepts by explaining them to others and providing guidance to junior students.
Show steps
Show steps
Show steps
- Identify opportunities to mentor junior students in bioinformatics or related fields
- Provide guidance on course content, research projects, or career development
- Review and provide feedback on their work, offering constructive criticism and encouragement
Develop a Bioinformatic Pipeline
Show steps
Deepen understanding of bioinformatics tools and workflows by creating a custom pipeline for NGS data analysis.
Show steps
Show steps
Show steps
- Identify the specific analysis tasks to be included in the pipeline
- Select and integrate appropriate bioinformatics tools for each task
- Develop a workflow that automates the execution of these tools
- Test and validate the pipeline using sample data
Career center
Learners who complete Genetics and Next Generation Sequencing for Bioinformatics will develop knowledge and skills
that may be useful to these careers:
Bioinformatics Scientist
Bioinformatics Scientist
A Bioinformatics Scientist studies biological information stored in databases, which are used to answer questions about the genetic makeup of living organisms, to develop new drugs, and to understand the causes and progression of disease. This course would be useful for you as it covers the basics of genetics and next-generation sequencing, which are essential for a career in bioinformatics.
Geneticist
Geneticist
A Geneticist studies the inheritance and variation of genes. They work with DNA to identify the genetic basis of diseases, and develop new treatments for genetic disorders. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in genetics.
Computational Biologist
Computational Biologist
Computational Biologists develop and use computational techniques to solve problems in biology and medicine. They analyze large datasets to identify patterns and trends, and use this information to develop new models and algorithms for understanding biological systems. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in computational biology.
Molecular Biologist
Molecular Biologist
A Molecular Biologist studies the structure and function of molecules, particularly DNA and RNA. They work with DNA to identify the genetic basis of diseases, and develop new treatments for genetic disorders. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in molecular biology.
Research Scientist
Research Scientist
A Research Scientist conducts research in a specific field of science, such as genetics or biology. They use their knowledge of genetics and next-generation sequencing to develop new treatments for diseases and improve our understanding of the human body. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in research science.
Physician
Physician
A Physician is a medical doctor who treats patients with diseases and injuries. They use their knowledge of genetics and next-generation sequencing to diagnose and treat genetic disorders. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in medicine.
Statistician
Statistician
A Statistician uses statistics to analyze data and draw conclusions. They work with data to identify patterns and trends, and use this information to develop models and algorithms for making predictions. This course would be useful for you as it provides a foundation in the basics of statistics, which are essential for a career in statistics.
Teacher
Teacher
A Teacher teaches students about a specific subject, such as genetics or biology. They use their knowledge of genetics and next-generation sequencing to teach students about the basics of these subjects. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in teaching.
Technical Writer
Technical Writer
A Technical Writer writes technical documents, such as manuals, reports, and articles. They use their knowledge of genetics and next-generation sequencing to write about these subjects in a clear and concise way. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in technical writing.
Data Scientist
Data Scientist
A Data Scientist uses data to solve problems and make predictions. They work with large datasets to identify patterns and trends, and use this information to develop models and algorithms for making predictions. This course would be useful for you as it provides a foundation in the basics of genetics and next-generation sequencing, which are essential for a career in data science.
For more career information including salaries, visit:
OpenCourser.com/course/vh9t24/genetics
Reading list
We've selected nine books
that we think will supplement your
learning. Use these to
develop background knowledge, enrich your coursework, and gain a
deeper understanding of the topics covered in
Genetics and Next Generation Sequencing for Bioinformatics.
Provides a comprehensive overview of bioinformatics programming using Python. It would be useful for students who want to learn more about the field or who are planning to take additional courses in bioinformatics programming.
Provides a comprehensive overview of bioinformatics and functional genomics. It would be useful for students who want to learn more about the field or who are planning to take additional courses in bioinformatics.
Save
Provides a comprehensive overview of bioinformatics. It would be useful for students who want to learn more about the field or who are planning to take additional courses in bioinformatics.
Provides a comprehensive overview of molecular biology. It would be useful for students who want to learn more about the field or who are planning to take additional courses in biology.
Provides a comprehensive overview of computational genomics using R. It would be useful for students who want to learn more about the field or who are planning to take additional courses in computational genomics.
Save
Provides a more in-depth look at genetics and genomics than the course covers. It would be useful for students who want to learn more about the field or who are planning to take additional courses in genetics.
Save
Provides a comprehensive overview of genetics. It would be useful for students who want to learn more about the field or who are planning to take additional courses in genetics.
Provides a comprehensive overview of big data in bioinformatics. It would be useful for students who want to learn more about the field or who are planning to take additional courses in big data in bioinformatics.
Save
Provides a comprehensive overview of biostatistics. It would be useful for students who want to learn more about the field or who are planning to take additional courses in biostatistics.
For more information about how these books relate to this course, visit:
OpenCourser.com/course/vh9t24/genetics
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Effort
3 total hours
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Good to know
Suitable for beginners seeking an introduction to Next Generation Sequencing Analysis
Provides a foundation in Biology prerequisites and quality control
Includes a step-by-step guided project for assessing and improving Illumina sequencing data quality
Assumes basic Biology and Chemistry knowledge at a high school level
Lacks coverage of advanced data analysis techniques
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