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Tom Spits, Michael Chang (educator), Marianna Bevova, Liesbeth Veenhoff "educator", Gerald de Haan, Floris Foijer (educator), Eugene Berezikov (educator), Peter Lansdorp (educator), Ellen Nollen (educator), Cornelis F. Calkhoven (educator), Maria Colome Tatche "educator", and Victor Guryev (educator)

Most FutureLearn courses run multiple times. Every run of a course has a set start date but you can join it and work through it after it starts. Find out more The course is aimed at anyone interested in understanding the biology of ageing. It requires basic knowledge of biology, though most of the terms are explained and you will receive further support via additional reading. You can use the hashtag #FLAgeing to talk about this course on social media.

Topics Covered

Read more

Most FutureLearn courses run multiple times. Every run of a course has a set start date but you can join it and work through it after it starts. Find out more The course is aimed at anyone interested in understanding the biology of ageing. It requires basic knowledge of biology, though most of the terms are explained and you will receive further support via additional reading. You can use the hashtag #FLAgeing to talk about this course on social media.

Topics Covered

  • Cellular ageing
  • Chromosomes and ageing
  • Genomic instability and epigenetics
  • Stem cells in ageing and rejuvenation
  • Molecular aspects of health and disease during ageing
  • Genetics and evolution of ageing

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Reviews summary

Molecular ageing: clear, comprehensive, and level-dependent

According to learners, this course offers a comprehensive overview of the molecular mechanisms of ageing. Many found the clear explanations by the knowledgeable lecturers helped break down complex topics, making the content accessible. However, student experiences varied significantly based on their prior biology knowledge. Some found it perfectly pitched with just basic biology, while others with stronger backgrounds felt it was a high-level overview lacking depth. Conversely, some with limited background found it challenging. The quizzes are seen by some as helpful for reinforcing concepts.
Assess and reinforce learning.
"Quizzes reinforce learning effectively."
"The quizzes were tricky, and I felt lost quickly."
"I sometimes struggled with the pace and assumed prior knowledge... quizzes..."
Fit depends on prior knowledge.
"Excellent course! ... accessible even with just basic biology knowledge."
"Fantastic introduction! I had a strong biology background and found this course a perfect way to get into the molecular aspects of ageing research."
"This course was quite difficult for me. I only had high school biology and found the concepts and terminology overwhelming. ... Maybe better suited for university students than general learners."
"Found this course okay. ... I sometimes struggled with the pace and assumed prior knowledge, even with the 'basic biology' prerequisite."
Instructors present topics effectively.
"The lecturers explain complex ideas clearly..."
"The lecturers are knowledgeable."
"The way they are presented is very engaging."
Breaks down complex topics well.
"The lecturers explain complex ideas clearly, making it accessible even with just basic biology knowledge."
"A solid course that demystifies the science of ageing. It connects various biological concepts in a logical flow."
"This course was quite difficult for me. I only had high school biology and found the concepts and terminology overwhelming. ... Felt lost quickly."
Broad introduction to ageing biology.
"Provides a comprehensive overview of the key molecular pathways involved in ageing."
"Good course, covers a lot of ground from chromosomes to stem cells."
"Useful as a foundation, but I'll need to do more reading for deeper understanding."
"It feels more like a high-level overview than a deep dive into mechanisms."

Career center

Learners who complete Why Do We Age? The Molecular Mechanisms of Ageing will develop knowledge and skills that may be useful to these careers:

Reading list

We've selected 45 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Why Do We Age? The Molecular Mechanisms of Ageing.
A classic work of popular science that presents a compelling case for evolution. Dawkins uses clear and concise language to explain the evidence for evolution, from the fossil record to the genetic code. must-read for anyone who wants to understand the science of evolution.
Classic textbook of molecular biology, covering all aspects of the field.
This comprehensive textbook covers all aspects of genetics, including a thorough discussion of chromosomes.
This textbook provides a comprehensive overview of genetics and genomics with a strong focus on their relevance to medicine. It's an excellent resource for medical students and those in related fields, covering fundamental genetic principles, clinical applications, and the impact of genomic technologies on healthcare.
Co-authored by one of the pioneers of CRISPR technology, this book provides an insightful look into the world of gene editing. It discusses the science behind CRISPR and its potential implications for medicine and evolution, while also addressing the ethical considerations. This crucial read for understanding contemporary genetics and the future of genetic engineering.
A widely used textbook in medical schools and genetics programs, this book focuses on the principles of human genetics and their application in medicine. It covers Mendelian inheritance, chromosomal disorders, molecular genetics of human disease, and genetic counseling. This core resource for students pursuing careers in healthcare and medical research.
This textbook provides a detailed and up-to-date account of human molecular genetics. It covers the molecular basis of human genetic variation, disease, and gene therapy. It is an essential resource for students and researchers in human genetics, medical genetics, and molecular biology. is suitable for advanced undergraduate and graduate levels and serves as a key reference in the field.
Provides a comprehensive overview of statistical methods used in epigenetics, guiding researchers in designing and analyzing epigenetics data.
Provides a comprehensive overview of genetics, including molecular biology.
Provides a comprehensive overview of molecular biology techniques.
A highly influential popular science book that presents a gene-centered view of evolution. While not a genetics textbook in the traditional sense, it provides a compelling framework for understanding how genes can influence behavior and evolution. It's an excellent book for gaining a broader perspective on genetics within the context of evolutionary biology and is considered a must-read for anyone interested in the subject.
Provides an accessible introduction to the field of epigenetics, explaining how gene expression can be modified without alterations to the underlying DNA sequence. It discusses the mechanisms and implications of epigenetics in development, disease, and inheritance. This is an important book for understanding a rapidly evolving area of genetics.
An accessible and engaging overview of human evolution, from our earliest ancestors to the present day. Written by a renowned anthropologist and science communicator, this book is perfect for anyone interested in learning more about where we come from.
A fascinating exploration of the evolutionary history of the human body. Shubin traces our origins back to the earliest fish and shows how our bodies have been shaped by millions of years of evolution. great choice for anyone who wants to learn more about the human body and its place in the natural world.
A fascinating exploration of the new science of evolutionary developmental biology. Carroll shows how the genes that control development have played a major role in the evolution of new species. great choice for anyone who wants to learn more about the latest research on evolution.
This textbook offers a comprehensive introduction to genetics, bridging classical genetics with modern genomics. It's well-regarded for its clear explanations and coverage of a wide range of topics, making it suitable for undergraduate students. It provides a strong foundation for understanding both the basic principles and the application of genomic technologies.
Delves into the complex nature of heredity, moving beyond simple Mendelian inheritance to explore the various ways traits are passed down and the factors that influence them. It covers topics like epigenetics, the microbiome, and the history of heredity research. It's a thought-provoking read for gaining a deeper and more nuanced understanding of inheritance.
This widely-used textbook provides a broad introduction to genetics, covering both classical and molecular genetics principles. It's well-suited for undergraduate students gaining a fundamental understanding of the subject. The book's clear language and comprehensive coverage make it a solid resource for building a strong base in genetics. It is often used as a core textbook in introductory genetics courses.
Written by a leading researcher in the field of ancient DNA, this book explores how the study of ancient genomes is revolutionizing our understanding of human history and evolution. It discusses major migrations, interbreeding with extinct human relatives, and the genetic basis of human diversity. is valuable for those interested in the intersection of genetics, anthropology, and archaeology.
Another popular textbook for introductory genetics, this book emphasizes fundamental concepts and their applications. It includes case studies and focuses on making genetics accessible to students. It's a comprehensive resource suitable for undergraduate students and is frequently adopted for genetics courses.
A classic in the field of molecular biology, this book provides a comprehensive and detailed exploration of the molecular mechanisms underlying genetic processes. It's suitable for advanced undergraduate and graduate students seeking a deep understanding of DNA replication, transcription, translation, and gene regulation. While foundational, newer editions incorporate contemporary findings, making it a valuable reference.
This popular science book explores the human genome by dedicating a chapter to each chromosome. It discusses the genes found on each chromosome and their relation to human traits, diseases, and evolution. It's an engaging read for gaining a broad understanding of the human genome and its significance.
This textbook focuses on the experimental approaches used in modern genetics, integrating classical genetic analysis with genomic approaches. It's suitable for advanced undergraduate students and provides insights into how geneticists design experiments and interpret data. It complements conceptual textbooks by focusing on the practical aspects of genetic research.
A classic work on the application of game theory to evolution. Maynard Smith shows how game theory can be used to understand the evolution of cooperation, altruism, and other complex behaviors. valuable resource for anyone who wants to understand the mathematical foundations of evolutionary theory.
Provides a detailed overview of the structure and function of human chromosomes.
A comprehensive and detailed textbook covering molecular genetics and genomics. It's a valuable resource for advanced undergraduate and graduate students, delving deep into gene structure, function, and regulation. is often used as a reference and is known for its in-depth coverage of molecular mechanisms. Newer editions are available, but the core content remains highly relevant.
A comprehensive overview of the evolution of sex. Miller examines the different theories about why sex evolved and how it has shaped the evolution of life. valuable resource for anyone who wants to understand the evolution of sex and its implications for human society.
This foundational and comprehensive laboratory manual for molecular biology techniques, including many essential to genetics research. While not a textbook for theoretical concepts, it is an indispensable reference for anyone performing experiments in molecular genetics. It provides detailed protocols and background information on a wide range of techniques. crucial reference tool for researchers and advanced students.
A Pulitzer Prize-winning book that explores the history of mass extinctions on Earth and the potential for a sixth extinction in the near future. Kolbert writes with clarity and eloquence about the complex scientific and ethical issues surrounding extinction.
A clear and concise introduction to the theory of evolution. Coyne uses everyday examples to explain the basic principles of evolution, such as natural selection and genetic drift. great choice for anyone who wants to learn more about the science of evolution.
This classic provides a personal and engaging account of the discovery of the structure of DNA. While not a textbook, it offers a unique historical perspective on a pivotal moment in genetics. It's valuable for understanding the scientific process and the personalities involved, providing a human element to the history of the field. is more valuable as additional reading to complement technical knowledge.
Provides an introduction to the science and applications of stem cell research, covering topics such as the history of stem cell research, stem cell biology, and the potential clinical applications of stem cells. It valuable resource for students and those new to the field of stem cell biology.
Provides a detailed overview of the potential clinical applications of stem cell research, covering topics such as the use of stem cells to treat diseases and injuries. It valuable resource for researchers and clinicians working in the field of stem cell biology.
Provides a comprehensive overview of the field of stem cell regenerative medicine, covering topics such as the use of stem cells to treat diseases and injuries. It valuable resource for researchers and clinicians working in the field of stem cell biology.
Explores the concept of higher dimensions and their potential implications for evolution. While not directly about evolution, it does offer a fascinating glimpse into the larger context of our universe and its potential impact on the evolution of life.
Provides a detailed overview of the role of stem cells in cancer, covering topics such as the use of stem cells to develop new cancer therapies. It valuable resource for researchers and clinicians working in the field of stem cell biology.
Provides a detailed overview of the role of stem cells in aging, covering topics such as the use of stem cells to rejuvenate old tissues and organs. It valuable resource for researchers and clinicians working in the field of stem cell biology.

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