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Epigenetic Control of Gene Expression

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1 The course will re-open in 2022.

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Rating 4.7★ based on 146 ratings
Length 8 weeks
Effort 7 weeks of study, 6-8 hours/week
Starts Aug 7 (38 weeks ago)
Cost $49
From The University of Melbourne via Coursera
Instructor Dr. Marnie Blewitt
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Medicine And Healthcare Biology Basic Science

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What people are saying

dr. marnie blewitt

I felt her love to the topic with the words and representation the professor done in this course I wish for her the best and to keep passion about the epigenetics as well as continue to add to our knowledge and teach us more and more An amazing course directed wonderfully by Dr. Marnie Blewitt.

Very nicely prepared and elucidated by Dr. Marnie Blewitt .Many many thanks to Dr. Marnie Blewitt & Coursera team.

I am grateful to Dr. Marnie Blewitt, the curator, Ms. Natasha Jansz, the moderator, and her colleagues and also the University of Melbourne for an excellent journey of learning.

A big thank you to Dr. Marnie Blewitt for helping us learn in a fun way!

I especially value Dr. Marnie Blewitt and her way to explain these phenomena in a clear and understandable way.

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learnt a lot

Thanks to the course I've learnt a lot about Epigenetic and now I feel confident to read and understand all the papers in this field of knowledge.

I certainly learnt a lot.

I enjoyed and learnt a lot about epigenetics by taking part in this great course.

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interested in genetics

I took this course as I was already very interested in genetics and considering doing my undergraduates degree in that rather than medicine or "pure" biology.

If you are interested in genetics, you will love this take on epigenetics; definitely worth it.

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very informative

Very informative.

Very informative!

Great and Very informative Course Its really a fascinating course to learn epigenetics, all classes and materials were really helpful nice Very good and useful This course is well taught and some important concepts are repeated over and over again during the course so the concept lingers in the brain as if it was there already.

A very informative course which starts from the basics and goes up all the way and the pace of the course is also perfectly set for anyone from professionals to first-timers.

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epigenetic control

Excellent introduction of epigenetics.Hopefully, in the future the course could incorporate new materials (advanced research) in epigenetic control in developmental biology and cancer biology.

this course gave a general ideal about epigenetic control, and it is helpful to me, Thanks I have taken this course in the past.

Great delivery The course on epigenetic control had the perfect balance between depth and accessibility.

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strongly recommend

I strongly recommend this course, I learned a lot more than I expected to learn.

I'd strongly recommend it to prospective students and academicians.

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my first

This was my first online course and I am delighted to say that it was a wonderful experience and I gained immense insight into the field of Epigenetics.

It was my first MOOC.

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best courses

This is one of the best courses in terms of science.

One of the best courses I have been through.

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Rating 4.7★ based on 146 ratings
Length 8 weeks
Effort 7 weeks of study, 6-8 hours/week
Starts Aug 7 (38 weeks ago)
Cost $49
From The University of Melbourne via Coursera
Instructor Dr. Marnie Blewitt
Download Videos On all desktop and mobile devices
Language English
Subjects Science
Tags Life Sciences Medicine And Healthcare Biology Basic Science

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