Currently, countries around the world have launched their own brain plans and listed neuroscience research as a strategic development direction. For example, in 2013, the United States launched the BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies, carrying out brain research through promoting innovative neurotechnologies) plan; in 2021, China launched Science and Technology Innovation 2030 - a major plan for "brain science and brain-inspired research". "Neurophotonics" came into being and has developed rapidly in recent years, becoming an emerging cutting-edge interdisciplinary subject. Neurophotonics research will not only help reveal the laws of brain cognitive development and provide evidence for disease diagnosis and treatment, but will also promote the development of brain-computer interfaces, artificial intelligence and other fields. However, there are no relevant monographs in the world that systematically introduce this emerging discipline.
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Currently, countries around the world have launched their own brain plans and listed neuroscience research as a strategic development direction. For example, in 2013, the United States launched the BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies, carrying out brain research through promoting innovative neurotechnologies) plan; in 2021, China launched Science and Technology Innovation 2030 - a major plan for "brain science and brain-inspired research". "Neurophotonics" came into being and has developed rapidly in recent years, becoming an emerging cutting-edge interdisciplinary subject. Neurophotonics research will not only help reveal the laws of brain cognitive development and provide evidence for disease diagnosis and treatment, but will also promote the development of brain-computer interfaces, artificial intelligence and other fields. However, there are no relevant monographs in the world that systematically introduce this emerging discipline.
Currently, countries around the world have launched their own brain plans and listed neuroscience research as a strategic development direction. For example, in 2013, the United States launched the BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies, carrying out brain research through promoting innovative neurotechnologies) plan; in 2021, China launched Science and Technology Innovation 2030 - a major plan for "brain science and brain-inspired research". "Neurophotonics" came into being and has developed rapidly in recent years, becoming an emerging cutting-edge interdisciplinary subject. Neurophotonics research will not only help reveal the laws of brain cognitive development and provide evidence for disease diagnosis and treatment, but will also promote the development of brain-computer interfaces, artificial intelligence and other fields. However, there are no relevant monographs in the world that systematically introduce this emerging discipline.
Since the fall semester of 2018, Tsinghua University has launched the "Neurophotonics" course for graduate students (or senior undergraduates) in optical engineering, biomedical engineering and other majors to introduce "Neurophotonics" to graduate students or senior undergraduates in related majors. "Study" biological background knowledge, related research techniques, and explore future development directions.
"Neurophotonics" is a discipline that uses optical technology to carry out neuroscience research. The content mainly includes the use of optical technology to image neural structure and function and the use of optical technology to control neural activity. This course starts from the significance and methods of brain science research and introduces the irreplaceable advantages of neurophotonics research. It then discusses tissue optics and introduces the rules of light propagation in neural tissue based on the basic knowledge of neurobiology. Then, it starts from linear The two aspects of optics and nonlinear optics introduce neural structure and functional imaging technology; in addition, a neural activity manipulation technology - optogenetics technology is introduced; finally, the current research hotspots and future development directions of neurophotonics are discussed.
This course is designed to introduce neuroscience to graduate students or senior undergraduates majoring in optical engineering, biomedical engineering, etc., and discuss new optical technologies and their application prospects in brain science research. It can also be used for graduate students majoring in neurobiology. Fundamentals of commonly used optical techniques provide opportunities. Through the study of this course, students can enhance their theoretical foundation and practical ability in the interdisciplinary subject of neurophotonics.
With the funding of the Tsinghua University Graduate Education and Teaching Reform Project (2019), this course has accumulated relevant course recording materials, which are now shared here in the hope of exchange and learning with peers and experts.
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Learning objectives
- Theoretical basis of brain science research
- Various optical technical means required for neural observation and regulation
- Theoretical basis of brain science research
- Various optical technical means required for neural observation and regulation
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Activities
Review anatomy and physiology
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This course is based on a thorough understanding of anatomy and physiology. Refreshing your knowledge in these areas will help you better grasp the advanced concepts and applications taught in this course.
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Anatomy
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-
Review chapters from your Human Biology or Anatomy and Physiology textbooks on the main body systems.
-
Take practice quizzes or use flashcards to test your knowledge of anatomy and physiology.
Review Fundamentals of Neural Science
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Review foundational concepts in neuroscience to build background knowledge necessary for understanding neurophotonics.
View
Principles of Neural Science, Fifth Edition...
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-
Read Chapter 1: Introduction
-
Read Chapter 2: Basic Principles of Neuronal Function
-
Make notes on key concepts and terminologies
Explore the basics of neuroimaging techniques
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This course covers advanced neuroimaging techniques. Understanding the basics of fMRI, EEG, and MEG will provide a strong foundation for your learning.
Show steps
-
Watch introductory tutorials on neuroimaging techniques on YouTube or Coursera.
-
Read articles or blog posts that explain the principles and applications of fMRI, EEG, and MEG.
Seven other activities
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Solve problems related to optical imaging and neural signal processing
Show steps
This course requires you to apply optical imaging and neural signal processing techniques to solve real-world problems. Completing practice drills will enhance your problem-solving skills and deepen your understanding of the material.
Show steps
-
Find practice problems online or in textbooks related to optical imaging and neural signal processing.
-
Set aside dedicated time each week to work on these problems.
-
Compare your solutions with those provided by experts or instructors.
Explain the Principles of Tissue Optics
Show steps
Develop a deeper understanding of tissue optics and its implications for neurophotonics research.
Show steps
-
Summarize the basic principles of tissue optics
-
Describe how these principles apply to light propagation in brain tissue
-
Create a visual representation or diagram illustrating the key concepts
Solve Problems on Neural Structure Imaging
Show steps
Enhance problem-solving skills in neural structure imaging techniques, such as linear and nonlinear optics.
Show steps
-
Review the concepts of linear and nonlinear optics
-
Practice solving problems involving light-tissue interactions in neural tissue
-
Analyze the results and interpret images obtained from neural structure imaging techniques
Explore Optogenetics Techniques
Show steps
Gain hands-on experience with optogenetics techniques to enhance understanding of neural activity manipulation.
Show steps
-
Find online tutorials or resources on optogenetics
-
Follow step-by-step instructions to set up and perform optogenetic experiments
-
Analyze the experimental results and draw conclusions
Develop a Research Proposal on Neurophotonics
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Apply knowledge gained in neurophotonics to develop a research proposal that addresses current challenges and future directions in the field.
Browse courses on
Artificial Intelligence
Show steps
-
Identify a specific research topic in neurophotonics
-
Conduct a literature review to gather background information
-
Formulate a research question and hypotheses
-
Design a research plan outlining methods and expected outcomes
-
Write a research proposal document
Mentor Undergraduate Students in Neurophotonics
Show steps
Enhance understanding of neurophotonics concepts by mentoring undergraduate students in the field.
Show steps
-
Volunteer as a mentor at a local university or research institution
-
Provide guidance to undergraduate students working on neurophotonics projects
-
Share knowledge and expertise in the field
Contribute to Open Source Neurophotonics Software
Show steps
Contribute to the development of open source software tools used in neurophotonics research.
Browse courses on
Open Source Software
Show steps
-
Identify open source neurophotonics software projects
-
Find areas where you can contribute your skills
-
Join the project community and contribute code, documentation, or other resources
Review anatomy and physiology
Show steps
This course is based on a thorough understanding of anatomy and physiology. Refreshing your knowledge in these areas will help you better grasp the advanced concepts and applications taught in this course.
Browse courses on
Anatomy
Show steps
- Review chapters from your Human Biology or Anatomy and Physiology textbooks on the main body systems.
- Take practice quizzes or use flashcards to test your knowledge of anatomy and physiology.
Review Fundamentals of Neural Science
Show steps
Review foundational concepts in neuroscience to build background knowledge necessary for understanding neurophotonics.
View
Principles of Neural Science, Fifth Edition...
on Amazon
Show steps
- Read Chapter 1: Introduction
- Read Chapter 2: Basic Principles of Neuronal Function
- Make notes on key concepts and terminologies
Explore the basics of neuroimaging techniques
Show steps
This course covers advanced neuroimaging techniques. Understanding the basics of fMRI, EEG, and MEG will provide a strong foundation for your learning.
Show steps
- Watch introductory tutorials on neuroimaging techniques on YouTube or Coursera.
- Read articles or blog posts that explain the principles and applications of fMRI, EEG, and MEG.
Solve problems related to optical imaging and neural signal processing
Show steps
This course requires you to apply optical imaging and neural signal processing techniques to solve real-world problems. Completing practice drills will enhance your problem-solving skills and deepen your understanding of the material.
Show steps
- Find practice problems online or in textbooks related to optical imaging and neural signal processing.
- Set aside dedicated time each week to work on these problems.
- Compare your solutions with those provided by experts or instructors.
Explain the Principles of Tissue Optics
Show steps
Develop a deeper understanding of tissue optics and its implications for neurophotonics research.
Show steps
- Summarize the basic principles of tissue optics
- Describe how these principles apply to light propagation in brain tissue
- Create a visual representation or diagram illustrating the key concepts
Solve Problems on Neural Structure Imaging
Show steps
Enhance problem-solving skills in neural structure imaging techniques, such as linear and nonlinear optics.
Show steps
- Review the concepts of linear and nonlinear optics
- Practice solving problems involving light-tissue interactions in neural tissue
- Analyze the results and interpret images obtained from neural structure imaging techniques
Explore Optogenetics Techniques
Show steps
Gain hands-on experience with optogenetics techniques to enhance understanding of neural activity manipulation.
Show steps
- Find online tutorials or resources on optogenetics
- Follow step-by-step instructions to set up and perform optogenetic experiments
- Analyze the experimental results and draw conclusions
Develop a Research Proposal on Neurophotonics
Show steps
Apply knowledge gained in neurophotonics to develop a research proposal that addresses current challenges and future directions in the field.
Browse courses on
Artificial Intelligence
Show steps
- Identify a specific research topic in neurophotonics
- Conduct a literature review to gather background information
- Formulate a research question and hypotheses
- Design a research plan outlining methods and expected outcomes
- Write a research proposal document
Mentor Undergraduate Students in Neurophotonics
Show steps
Enhance understanding of neurophotonics concepts by mentoring undergraduate students in the field.
Show steps
- Volunteer as a mentor at a local university or research institution
- Provide guidance to undergraduate students working on neurophotonics projects
- Share knowledge and expertise in the field
Contribute to Open Source Neurophotonics Software
Show steps
Contribute to the development of open source software tools used in neurophotonics research.
Browse courses on
Open Source Software
Show steps
- Identify open source neurophotonics software projects
- Find areas where you can contribute your skills
- Join the project community and contribute code, documentation, or other resources
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