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Literature Case Studies in Drug Discovery

Erland Stevens

In this course about drug discovery case studies, students will read five different Drug Annotations articles. Each article will require approximately two hours to read thoroughly and fully process. Including assessment questions based on the articles, the full course should require no more than 15 hours of effort.

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In this course about drug discovery case studies, students will read five different Drug Annotations articles. Each article will require approximately two hours to read thoroughly and fully process. Including assessment questions based on the articles, the full course should require no more than 15 hours of effort.

Students in the course should understand lead selection, lead optimization, pharmacodynamics, drug activity, pharmacokinetics, and preclinical safety. A fundamental understanding of the structure of organic molecules and their functional groups is also required. The course has no structure beyond having a module for each case study article. A handful of 10-15-minute videos with discussions of other Drug Annotation articles are provided for reference. Each module provides a link to the open access article on the Journal of Medicinal Chemistry website.

Students signed up for the Audit Track have access to the links to the case studies and the sample Drug Annotation article videos. Students enrolled through the Verified Track also have access to assessment questions.

What you'll learn

Students will learn about several drug programs in the pharmaceutical industry…

  • AZD4831 – a compound that reduces incidence of heart failure

  • MRTX0902 – a compound with anti-tumor activity

  • pritelivir – a compound that treats herpes simplex virus infections

  • reldesemitiv -a compound that treats impaired muscle function

  • sebetralstat – a compound that treats hereditary angioedema

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Helps students become more familiar with how the drug discovery and development process works
Offers meticulously designed case studies that closely follow real-world examples
Provides learners with a strong foundation in the fundamentals of drug discovery
Useful for students pursuing careers in the pharmaceutical industry or related fields
Requires a basic understanding of organic chemistry and pharmacology
May not be suitable for complete beginners in the field of drug discovery

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Activities

Coming soon We're preparing activities for Literature Case Studies in Drug Discovery. These are activities you can do either before, during, or after a course.

Career center

Learners who complete Literature Case Studies in Drug Discovery will develop knowledge and skills that may be useful to these careers:
Science Librarian
A Science Librarian is an expert in drug discovery and pharmaceutical research. This course may contribute to your success as a Science Librarian by providing you with a deep knowledge of the drug discovery process.
Clinical Research Associate
As a Clinical Research Associate, you would be in charge of evaluating the safety of new medical treatments, such as drugs. The topics covered in this course, including drug activity and preclinical safety, would be very useful for you to have a solid foundation in this field.
Pharmaceutical Sales Representative
Pharmaceutical Sales Representatives help educate healthcare practitioners about new drugs and treatments. This course may be useful in this role, as you would learn a great deal about the properties of drugs and how they work.
Research Scientist
Research Scientists are responsible for conducting experiments and collecting data to further the knowledge of drug discovery. The topics covered in this course would provide you with a good understanding of the fundamentals of drug discovery, which would be very helpful in this role.
Toxicologist
Toxicologists determine the potential health hazards of substances, such as drugs and chemicals. This course may be useful in this role, as you would learn about drug activity and preclinical safety, among other topics.
Medical Writer
Medical Writers are responsible for writing and editing scientific and medical content, such as drug information sheets and clinical trial reports. This course may be useful in this role, as it covers several topics that a Medical Writer should be familiar with, such as drug activity and pharmacokinetics.
Biostatistician
Biostatisticians apply statistical methods to data in the field of biology, including drug discovery. The topics covered in this course, especially pharmacokinetics, will be helpful to have a better understanding of this field.
Biomedical Engineer
Biomedical Engineers typically design and create equipment and devices used in the medical field, including some used in drug discovery. This course will be useful by providing you with a basic knowledge of the drug discovery process and the properties of drugs.
Chemist
Chemists are responsible for developing and studying new chemicals and compounds, including those used in drugs. Understandably, pharmacists will benefit from learning about the drug discovery process.
Physician
Physicians prescribe and administer drugs to patients, which is why a course that covers drug discovery case studies may increase your knowledge of drugs and how they work. It may also be of interest as a refresher for physicians who work in research.
Pharmacist
Pharmacists dispense and advise on the use of drugs, which is why learning about the drug discovery process can be a very beneficial supplement to your existing knowledge as a Pharmacist.
Patent Attorney
Patent Attorneys help clients obtain and protect their patents, including patents for new drugs and treatments. This course may be useful for a Patent Attorney who specializes in the pharmaceutical industry, as it can provide a deeper understanding of the drug discovery process.
Healthcare Consultant
Healthcare Consultants provide advice and guidance to healthcare organizations, such as hospitals and pharmaceutical companies. This course may be useful in this role, as it can provide you with a deeper understanding of the drug discovery process.
Epidemiologist
An Epidemiologist is a scientist who studies the distribution and patterns of health events and diseases in a population. While an understanding of drugs and the drug discovery process is not necessarily a requirement, it could be helpful depending on your area of focus.
Medical Laboratory Scientist
Medical Laboratory Scientists typically perform tests and analyze samples to help diagnose and treat diseases. This course will be useful by providing you with a deep understanding of the drug discovery process and the properties of drugs.

Reading list

We've selected seven books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Literature Case Studies in Drug Discovery.
Provides a comprehensive overview of medicinal chemistry, covering the principles of drug design, discovery, and development. It valuable resource for students and researchers in the field.
Classic textbook of pharmacology, providing a comprehensive overview of the field. It is an essential resource for students and researchers in the field.
Provides a molecular and biochemical approach to medicinal chemistry, covering the principles of drug design, discovery, and development. It valuable resource for students and researchers in the field.
Classic textbook of medicinal chemistry, providing a comprehensive overview of the field. It valuable resource for students and researchers in the field.
Provides a comprehensive overview of drug synthesis, covering the principles of drug design, discovery, and development. It valuable resource for students and researchers in the field.
Provides a comprehensive overview of drug metabolism and disposition, covering the principles of drug design, discovery, and development. It valuable resource for students and researchers in the field.
Provides a comprehensive overview of pharmaceutical chemistry, covering the principles of drug design, discovery, and development. It valuable resource for students and researchers in the field.

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