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Dr. Jennifer M. Groh, Ph.D.

This course is about how the brain creates our sense of spatial location from a variety of sensory and motor sources, and how this spatial sense in turn shapes our cognitive abilities.

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This course is about how the brain creates our sense of spatial location from a variety of sensory and motor sources, and how this spatial sense in turn shapes our cognitive abilities.

Knowing where things are is effortless. But “under the hood,” your brain must figure out even the simplest of details about the world around you and your position in it. Recognizing your mother, finding your phone, going to the grocery store, playing the banjo – these require careful sleuthing and coordination across different sensory and motor domains. This course traces the brain’s detective work to create this sense of space and argues that the brain’s spatial focus permeates our cognitive abilities, affecting the way we think and remember.

The material in this course is based on a book I've written for a general audience. The book is called "Making Space: How the Brain Knows Where Things Are", and is available from Amazon, Barnes and Noble, or directly from Harvard University Press.

The course material overlaps with classes on perception or systems neuroscience, and can be taken either before or after such classes.

Dr. Jennifer M. Groh, Ph.D.

Professor

Psychology & Neuroscience; Neurobiology

Duke University

www.duke.edu/~jmgroh

Jennifer M. Groh is interested in how the brain process spatial information in different sensory systems, and how the brain's spatial codes influence other aspects of cognition. She is the author of a recent book entitled "Making Space: How the Brain Knows Where Things Are" (Harvard University Press, fall 2014).

Much of her research concerns differences in how the visual and auditory systems encode location, and how vision influences hearing. Her laboratory has demonstrated that neurons in auditory brain regions are sometimes responsive not just to what we hear but also to what direction we are looking and what visual stimuli we can see. These surprising findings challenge the prevailing assumption that the brain’s sensory pathways remain separate and distinct from each other at early stages, and suggest a mechanism for such multi-sensory interactions as lip-reading and ventriloquism (the capture of perceived sound location by a plausible nearby visual stimulus).

Dr. Groh has been a professor at Duke University since 2006. She received her undergraduate degree in biology from Princeton University in 1988 before studying neuroscience at the University of Michigan (Master’s, 1990), the University of Pennsylvania (Ph.D., 1993), and Stanford University (postdoctoral, 1994-1997). Dr. Groh has been teaching undergraduate classes on the neural basis of perception and memory for over fifteen years. She is presently a faculty member at the Center for Cognitive Neuroscience and the Duke Institute for Brain Sciences at Duke University. She also holds appointments in the Departments of Neurobiology and Psychology & Neuroscience at Duke.

Dr. Groh’s research has been supported by a variety of sources including the John S. Guggenheim Foundation, the National Institutes of Health, the National Science Foundation, and the Office of Naval Research Young Investigator Program, the McKnight Endowment Fund for Neuroscience, the John Merck Scholars Program, the EJLB Foundation, the Alfred P. Sloan Foundation, the Whitehall Foundation, and the National Organization for Hearing Research.

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What's inside

Syllabus

Course Introduction and Vision (Part 1)
This module contains an introduction to the course as a whole (Video 1.1) and an exploration of how our eyes detect light and deduce the location light is coming from (Videos 1.2-1.6). You'll also learn about how scientists from Democritus to Alhazen to Kepler figured this out. The final video for the module involves an experiment to test what happens when special goggles turn the world upside down (Video 1.7). I'll show experiments frequently throughout this course -- they are how we know what we know. This module’s quiz is ungraded and available to both auditors and certificate students. Consider it a sample of the style of question in the quizzes for the remaining modules, and an opportunity to determine if you’d like to pursue a certificate for this course.
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Vision (Part 2), the Body, and Neural Signals
In this unit, we cover the visual scene in 3D - the many clues to depth. We then turn to body senses (position and touch) and how our brains detect the configuration of our own bodies. Along the way, we cover the resting membrane potential, the action potential, and how they arise. Finally, we bring vision and the body together, and throw some beanbags at a visual target while wearing prisms! This material is covered in Making Space, chapters 2 and 3.
Brain Maps
In this unit, we turn to the brain and how it uses the spatial position of neurons within the brain to organize information about the spatial position of stimuli in the world (Making Space chapter 4). You'll learn about how we identify where one object ends and another begins, what a receptive field is, and how some neurons are sensitive to edges and the boundaries of objects. Maps occur in both visual cortex and body (somatosensory) cortex, and these maps may be responsible for various "phantom" sensations (examples from normal vision, patients with body part amputations, and electrical stimulation experiments).
Sound and Brain Representations
In module 4, we turn to the fascinating puzzle of how we deduce sound location--a process that requires quite a bit of detective work. Our brains piece together multiple types of clues, including subtle differences in timing, loudness, frequency content, and how sounds appear to change as we turn our heads. Because our ears don't form images of sounds, our brains don't have to use maps to encode sound location. The second half of the videos this module concern alternative forms of brain representation, how the brain translates between different types of representation, and what we know about brain representations for sound location. The material is covered in chapter 5, "Sherlock Ears" and chapter 6, "Moving with Maps and Meters", in Making Space. Be forewarned, there are about 70 minutes of video this module, as compared to previous modules' 50-60 minutes. After watching the full set, you'll see why these videos are grouped together as a unit. To make things more manageable, we've broken the quiz into two parts; that way, you can get feedback on one part before moving on to the next, if you like.
Reference Frames and Navigation
This module we turn to how spatial locations are defined, and discuss the concept of a reference frame. Initially, reference frames are quite different for visual, auditory, and somatosensory information. Visual location is defined with respect to the eyes, whereas sound locations are detected with respect to the head and ears, and tactile locations are detected based on body surface position. As you'll see, the brain transforms these signals into new reference frames to facilitate interactions between these sensory systems. We then consider space on a larger scale, and ask how we know where we are and how we navigate from one place to another. Knowledge of self-motion relies in part on the vestibular system, our sense of balance. The vestibular system works in concert with vision and motor systems to update our sense of position and keep us from getting lost. This module's material is covered in chapters 7, "Your Sunglasses Are in the Milky Way", and 8, "Going Places" of Making Space.
Memory and Cognition
In this final module of the course, we build several important links between the sense of space and other kinds of cognition. Videos 6.1-6.5 concern the relationship between space and memory. Memory is reflected in multiple different kinds of neural mechanisms and involves multiple brain regions. The memory and spatial functions of these mechanisms and brain regions overlap. Video 6.5 in particular features work by John O'Keefe concerning response patterns known as "place fields" in the hippocampus, and work by May-Britt and Edvard Moser concerning grid cells. This seminal work was recognized by the 2014 Nobel Prize in Medicine and Physiology. Videos 6.6-6.9 turn to thought more generally, and present a series of theories and experiments that suggest that the brain is actually using sensory and motor structures to think and reason. Thus, our brain systems for space may be engaged in a wide set of mental functions, which are shaped by the multiple purposes of this neural infrastructure. This module's material is covered in chapters 9, "Space and Memory", and 10, "Thinking about Thinking" of Making Space. I hope you enjoy this synthesis of all you have learned and what it means!

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Develops an understanding of spatial cognition, a subject of interest to developmental psychologists, vision scientists, and cognitive psychologists
Examines the neuroscience of spatial sense and the role of vision, hearing, and body position in creating this sense of space
Introduces concepts such as receptive fields, visual mapping, and reference frames
Taught by Dr. Jennifer M. Groh, an expert in spatial cognition with published research on the topic
Offers multiple modes of engagement, including videos, readings, and quizzes
Covers a range of topics, from basic principles to current research findings

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Reviews summary

Beginner-friendly introduction to the brain and space

Learners say this engaging neuroscience course is well-paced and easy to follow. It's a good option for beginners and those with no prior neuroscience knowledge. Dr. Groh presents complex information with clear explanations and visual aids. The course covers topics such as vision, hearing, touch, and spatial navigation. Note that quizzes can be challenging but help reinforce learning.
The quizzes can be challenging but they help reinforce learning.
"Very interesting, I loved it ! Some concepts might be challenging but it is very well explained with lots of examples and concrete experiments for students to understand well."
"The course is really interesting and enjoyable. I loved the examples from the daily life."
"The supporting book for the course is also a good read."
The course is well-paced and easy to follow.
"I really enjoyed this learning experience. The instructor had a great way of presenting information, and went at a good pace that was comfortable for learning something completely new to me."
"This course represents a good start in order to study space and brain relationship."
The course is accessible to beginners and those with no prior neuroscience knowledge.
"This course was a good start for beginners in neuroscience and spatial cognition at a finer scale."
"This course was exactly the type of learning I was looking for in order to better understand our brain and how it perceives location and language acquisition."
"Great course. I loved Dr Groh and how simple she made it all feel"
The instructor, Dr. Jennifer Groh, is passionate, clear, and engaging.
"Dr Groh was so inspiring, passionate, clear and precise."
"I enjoyed this very rich and interesting course as a psychomotor therapist and a neurosciences lover, it will definitely help me in my career."
"Her ability to clearly communicate dense technical jargon is beyond commendable."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in The Brain and Space with these activities:
Practice using spatial navigation skills
Practicing spatial navigation skills will help you improve your ability to understand and apply the concepts covered in this course.
Show steps
  • Navigate a new neighborhood or city
  • Play a game that requires spatial navigation skills, such as Geocaching or Labyrinth
  • Use a map or GPS device to plan a route
Read 'Making Space: How the Brain Knows Where Things Are'
This book provides a comprehensive overview of the material covered in this course, and will help you better understand the concepts.
Show steps
  • Read one chapter of the book each week
  • Take notes on the main points of each chapter
  • Discuss the book with a classmate or friend
Watch video tutorials on spatial perception
Watching video tutorials will help you visualize the concepts you learn in class and reinforce your understanding.
Browse courses on Spatial Perception
Show steps
  • Find video tutorials online or on platforms like YouTube
  • Watch one or two videos each week
  • Take notes on the main points of each video
Five other activities
Expand to see all activities and additional details
Show all eight activities
Focus on spatial reasoning skills
Reviewing basic spatial reasoning skills will help you strengthen your foundation for this course.
Browse courses on Spatial Perception
Show steps
  • Take a practice quiz on spatial reasoning
  • Play a game that requires spatial reasoning skills, such as Tetris or Minecraft
  • Complete a puzzle that requires spatial reasoning skills, such as a jigsaw puzzle or a maze
Complete practice problems on spatial perception
Completing practice problems will help you improve your spatial perception skills and reinforce the concepts you learn in class.
Browse courses on Spatial Perception
Show steps
  • Find practice problems online or in a textbook
  • Set aside time each week to complete practice problems
  • Check your answers and identify areas where you need improvement
Join a study group or attend a peer tutoring session
Working with other students will help you learn the material more effectively and identify areas where you need improvement.
Show steps
  • Find a study group or peer tutoring session that fits your schedule
  • Attend the study group or peer tutoring session regularly
  • Participate actively in discussions and ask questions
Create a glossary of terms related to spatial perception
Creating a glossary will help you organize and retain the key terms and concepts covered in this course.
Browse courses on Spatial Perception
Show steps
  • Identify the key terms and concepts covered in this course
  • Define each term or concept in your own words
  • Organize the terms and concepts into a glossary
Create a presentation or video explaining a concept related to spatial perception
Creating a presentation or video will help you synthesize and apply your knowledge of spatial perception.
Browse courses on Spatial Perception
Show steps
  • Choose a concept related to spatial perception to explain
  • Research the concept and gather information from different sources
  • Create a presentation or video that explains the concept in a clear and engaging way
  • Share your presentation or video with others

Career center

Learners who complete The Brain and Space will develop knowledge and skills that may be useful to these careers:
Cognitive Psychologist
Cognitive Psychologists study the mental processes involved in acquiring, storing, and using knowledge. Cognitive Psychologists may specialize in a particular area of cognition, such as memory, attention, or language. This course may be useful for those interested in a career as a Cognitive Psychologist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of spatial cognition and memory.
Neuroscientist
Neuroscientists study the nervous system, a complex network of cells, tissues, and organs that work together to control all bodily functions, including thought, emotion, and movement. Neuroscientists may specialize in a particular area of the nervous system, such as the brain, spinal cord, or peripheral nerves. This course may be useful for those interested in a career as a Neuroscientist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of spatial cognition.
Neurologist
Neurologists diagnose and treat diseases of the nervous system, including the brain, spinal cord, and peripheral nerves. Neurologists may specialize in a particular area of neurology, such as epilepsy, stroke, or movement disorders. This course may be useful for those interested in a career as a Neurologist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of spatial cognition and neurological disorders.
Occupational Therapist
Occupational Therapists help people regain or improve their ability to perform everyday activities. Occupational Therapists may work with people of all ages, from infants to the elderly. This course may be useful for those interested in a career as an Occupational Therapist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of motor control and rehabilitation.
Speech-Language Pathologist
Speech-Language Pathologists assess and treat speech, language, and swallowing disorders. Speech-Language Pathologists may work with people of all ages, from infants to the elderly. This course may be useful for those interested in a career as a Speech-Language Pathologist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of speech and language disorders.
Physical Therapist
Physical Therapists help people regain or improve their ability to move. Physical Therapists may work with people of all ages, from infants to the elderly. This course may be useful for those interested in a career as a Physical Therapist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of motor control and rehabilitation.
School Psychologist
School Psychologists help children and adolescents with academic, social, and emotional problems. School Psychologists may work in a variety of settings, including schools, clinics, and hospitals. This course may be useful for those interested in a career as a School Psychologist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of child development and learning.
Rehabilitation Counselor
Rehabilitation Counselors help people with disabilities adjust to and live independently in their communities. Rehabilitation Counselors may work with people of all ages, from children to adults. This course may be useful for those interested in a career as a Rehabilitation Counselor because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of cognitive rehabilitation.
Audiologist
Audiologists assess and treat hearing and balance disorders. Audiologists may work with people of all ages, from infants to the elderly. This course may be useful for those interested in a career as an Audiologist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of hearing and balance disorders.
Optometrist
Optometrists examine eyes and diagnose and treat vision problems. Optometrists may also prescribe eyeglasses and contact lenses. This course may be useful for those interested in a career as an Optometrist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of vision disorders.
Physician Assistant
Physician Assistants are licensed healthcare professionals who work under the supervision of a physician. Physician Assistants may perform a variety of tasks, including taking medical histories, performing physical exams, and prescribing medications. This course may be useful for those interested in a career as a Physician Assistant because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of medical diagnosis and treatment.
Registered Nurse
Registered Nurses provide direct patient care and work under the supervision of a physician. Registered Nurses may work in a variety of settings, including hospitals, clinics, and nursing homes. This course may be useful for those interested in a career as a Registered Nurse because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of patient care.
Market Researcher
Market Researchers conduct research to help businesses understand their customers and markets. Market Researchers may work in a variety of industries, including technology, finance, and healthcare. This course may be useful for those interested in a career as a Market Researcher because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of consumer behavior.
Software Engineer
Software Engineers design, develop, and maintain computer software. Software Engineers may work in a variety of industries, including technology, finance, and healthcare. This course may be useful for those interested in a career as a Software Engineer because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of human-computer interaction.
Data Scientist
Data Scientists collect, analyze, and interpret data to help businesses make informed decisions. Data Scientists may work in a variety of industries, including technology, finance, and healthcare. This course may be useful for those interested in a career as a Data Scientist because it provides a foundation in the neural basis of perception and memory. It would be especially helpful for those interested in studying the neural basis of data analysis and interpretation.

Reading list

We've selected 13 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in The Brain and Space.
Written by the course instructor, this book provides a comprehensive and engaging overview of the neural and cognitive mechanisms underlying spatial cognition.
This advanced text explores the neural and cognitive processes involved in spatial cognition, including navigation and memory.
This comprehensive textbook provides a detailed account of the neural mechanisms underlying spatial navigation, with a particular focus on the role of the hippocampus.
This advanced text explores the neural and cognitive processes involved in learning, with a focus on the role of space in learning processes.
This interdisciplinary text examines the psychological and cognitive aspects of spatial cognition, with a focus on the role of space in memory, navigation, and decision-making.
This advanced text explores the neural and cognitive processes involved in thinking and problem solving, with a focus on the role of spatial cognition in these processes.
This classic text provides a comprehensive overview of visual perception, with a particular focus on the neural mechanisms underlying spatial processing.
This comprehensive textbook covers a broad range of topics in sensation and perception, providing a solid foundation for understanding the neural basis of spatial cognition.
This authoritative reference provides a detailed account of the neural mechanisms underlying auditory perception, including the processing of spatial cues.
This comprehensive handbook provides a detailed account of the field of memory research, including the role of spatial cognition in memory processes.
This comprehensive textbook provides a detailed account of the neural mechanisms underlying attention, with a particular focus on the role of spatial attention.
This comprehensive textbook provides a detailed account of the neural mechanisms underlying memory, including the role of spatial cognition in memory processes.
Provides a detailed overview of the neuroanatomy of the brain, with a particular focus on the neural pathways involved in spatial processing.

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