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Caitlin Mullarkey
and
Felicia Vulcu
Are you a living creature? Then, congratulations! You’ve got DNA. But how much do you really know about the microscopic molecules that make you unique?
Why is DNA called the “blueprint of life”?
What is a “DNA fingerprint”?
How do scientists clone DNA?
What can DNA teach you about your family history?
Are Genetically Modified Organisms (GMOs) safe?
Is it possible to revive dinosaurs by cloning their DNA?
Read more
Are you a living creature? Then, congratulations! You’ve got DNA. But how much do you really know about the microscopic molecules that make you unique?
Why is DNA called the “blueprint of life”?
What is a “DNA fingerprint”?
How do scientists clone DNA?
What can DNA teach you about your family history?
Are Genetically Modified Organisms (GMOs) safe?
Is it possible to revive dinosaurs by cloning their DNA?
Read more
Are you a living creature? Then, congratulations! You’ve got DNA. But how much do you really know about the microscopic molecules that make you unique?
Why is DNA called the “blueprint of life”?
What is a “DNA fingerprint”?
How do scientists clone DNA?
What can DNA teach you about your family history?
Are Genetically Modified Organisms (GMOs) safe?
Is it possible to revive dinosaurs by cloning their DNA?
DNA Decoded answers these questions and more. If you’re curious about DNA, join Felicia Vulcu and Caitlin Mullarkey, two biochemists from McMaster University, as they explore the structure of DNA, how scientists cracked the genetic code, and what our DNA can tell us about ourselves. Along the way, you’ll learn about the practical techniques that scientists use to analyze our genetic risks, to manipulate DNA, and to develop new treatments for a range of different diseases. Then, step into our virtual lab to perform your own forensic DNA analysis of samples from a crime scene and solve a murder.
Register for this course and see more details by visiting:
OpenCourser.com/course/r8a0jc/dna
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What's inside
Syllabus
Cracking the Genetic Code
In this module, we'll explore the molecular structure of DNA. What is DNA? What are the basic building blocks of DNA? Where can you find DNA within a cell? We'll learn about how James Watson and Francis Crick were able to solve the riddle of the molecular structure of DNA by building on the work of other scientists. Their groundbreaking discovery revealed that four nucleobases (adenine, thymine, cytosine, and guanine) combine with sugar and phosphate molecules to form the familiar double helix of DNA. We'll take a look at how the molecular structure of DNA regulates its functions; for example, how the chemical bonds (covalent and noncovalent) between these molecules allow DNA to "unzip" during replication. Then we'll take a look at how you manage to fit over three billion base pairs into each of your cells. (Here's a hint: Histones, nucleosomes, and chromosomes would be great at packing for a trip!)
Read more
Syllabus
Cracking the Genetic Code
In this module, we'll explore the molecular structure of DNA. What is DNA? What are the basic building blocks of DNA? Where can you find DNA within a cell? We'll learn about how James Watson and Francis Crick were able to solve the riddle of the molecular structure of DNA by building on the work of other scientists. Their groundbreaking discovery revealed that four nucleobases (adenine, thymine, cytosine, and guanine) combine with sugar and phosphate molecules to form the familiar double helix of DNA. We'll take a look at how the molecular structure of DNA regulates its functions; for example, how the chemical bonds (covalent and noncovalent) between these molecules allow DNA to "unzip" during replication. Then we'll take a look at how you manage to fit over three billion base pairs into each of your cells. (Here's a hint: Histones, nucleosomes, and chromosomes would be great at packing for a trip!)
Read more
Traffic lights
Traffic lights
Read about what's good
what should give you pause and
possible dealbreakers
Provides an accessible introduction to the structure and function of DNA, making it a valuable resource for beginners
Taught by two biochemists from McMaster University, ensuring high-quality content and subject matter expertise
Covers practical techniques used in forensic DNA analysis, providing hands-on learning opportunities
Examines the ethical implications of genetic engineering and GMOs, fostering critical thinking and ethical decision-making
Leverages real-world examples and case studies, making the learning experience more engaging and applicable
Provides a comprehensive overview of the field of DNA science, suitable for diverse audiences with varying knowledge levels
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Reviews summary
Engaging introduction to dna and genetics
According to students, DNA Decoded provides a clear and engaging introduction well-suited for beginners and those curious about genetics without prior scientific knowledge. Learners particularly highlight the engaging instructors and the coverage of interesting, real-world topics like forensic DNA analysis, genetic engineering, and personal ancestry. While the course offers a solid foundation, some reviewers note the depth might be limited for those with existing biology backgrounds, and the virtual lab experience, while informative, is a simulation rather than hands-on.
Lab simulation is informative but basic.
"The virtual lab was a neat idea, showing the steps, but it wasn't truly 'hands-on'."
"It was helpful to see the process demonstrated in the virtual lab."
"I understood the concepts from the virtual lab, though it was more of a walkthrough than interactive."
Covers interesting real-world DNA applications.
"Loved learning about the forensic science applications of DNA. It was fascinating!"
"The modules on genetic engineering and GMOs were really informative and well-balanced."
"Discovering how DNA relates to my personal ancestry was a highlight for me."
Provides a solid foundation in DNA basics.
"This course was a perfect starting point for someone like me who knew nothing about DNA."
"It felt like a great introduction to the world of genetics."
"Didn't need any prerequisites; they build everything from the ground up."
Simplifies complex biology concepts effectively.
"The instructors explained complex ideas in a way that was really easy to grasp."
"I found the explanations incredibly clear, even without any prior science background."
"Everything was presented logically and broken down into understandable chunks."
May be too basic or fast depending on background.
"For me, with some biology background, it felt a bit too basic at times."
"I wish they went into slightly more detail on some of the advanced techniques."
"Some parts moved a little fast, requiring rewinding lectures to catch everything."
Activities
Be better prepared
before
your course. Deepen your understanding
during
and
after
it. Supplement your coursework and achieve mastery of the topics covered
in DNA Decoded with these
activities:
Form a study group with classmates
Show steps
Collaborate with peers to discuss course material, share insights, and reinforce learning.
Show steps
-
Identify classmates who are interested in forming a study group
-
Establish regular meeting times and locations
-
Review course materials, discuss concepts, and work on problems together
-
Provide feedback and support to each other
Read 'The Double Helix' by James D. Watson
Show steps
Gain historical perspective on the discovery of DNA's structure and the development of molecular biology.
View
DNA
on Amazon
Show steps
Read molecular biology textbook
Show steps
Review key biological concepts and prepare for more advanced course material.
Browse courses on
Molecular Biology
Show steps
-
Collect any necessary reading materials
-
Break up reading into manageable chunks
-
Read and take notes on assigned chapters
-
Complete any end-of-chapter questions or exercises
Five other activities
Expand to see all activities and additional details
Show all eight activities
Complete Coursera's 'DNA and the Mystery of Life'
Show steps
Reinforce course concepts through interactive tutorials and hands-on activities.
Browse courses on
Molecular Biology
Show steps
-
Create a Coursera account
-
Enroll in the 'DNA and the Mystery of Life'
-
Complete each tutorial in the course
Solve online genetics problems
Show steps
Strengthen problem-solving skills and apply course concepts to real-world scenarios.
Browse courses on
Genetics
Show steps
-
Find a reputable online genetics problem database
-
Select problems at various difficulty levels
-
Work through the problems, checking your answers as you go
-
Review incorrect answers to identify areas for improvement
Develop a DNA replication infographic
Show steps
Enhance understanding of the complex process of DNA replication through visual representation.
Browse courses on
DNA Replication
Show steps
-
Gather information on the steps of DNA replication
-
Design a visually appealing infographic layout
-
Create clear and concise graphics and text to illustrate the process
-
Proofread and finalize the infographic
Contribute to open-source genetic databases
Show steps
Enhance research skills and contribute to the advancement of genetic knowledge by sharing data and collaborating with others.
Browse courses on
Genetics
Show steps
-
Identify reputable open-source genetic databases
-
Explore the databases and identify areas where you can contribute
-
Contribute data, annotations, or other relevant information
-
Collaborate with other contributors to ensure data quality and accuracy
Design a genetic experiment to test a hypothesis
Show steps
Apply course concepts to real-world research by designing and conducting your own genetic experiment.
Browse courses on
Genetics
Show steps
-
Identify a research question and hypothesis
-
Design the experiment, including methods and protocols
-
Obtain necessary materials and resources
-
Conduct the experiment and collect data
-
Analyze the data and draw conclusions
Form a study group with classmates
Show steps
Collaborate with peers to discuss course material, share insights, and reinforce learning.
Show steps
Show steps
Show steps
- Identify classmates who are interested in forming a study group
- Establish regular meeting times and locations
- Review course materials, discuss concepts, and work on problems together
- Provide feedback and support to each other
Read 'The Double Helix' by James D. Watson
Show steps
Gain historical perspective on the discovery of DNA's structure and the development of molecular biology.
View
DNA
on Amazon
Show steps
Show steps
Show steps
Read molecular biology textbook
Show steps
Review key biological concepts and prepare for more advanced course material.
Browse courses on
Molecular Biology
Show steps
Show steps
Show steps
- Collect any necessary reading materials
- Break up reading into manageable chunks
- Read and take notes on assigned chapters
- Complete any end-of-chapter questions or exercises
Five other activities
Expand to see all activities and additional details
Show all eight activities
Complete Coursera's 'DNA and the Mystery of Life'
Show steps
Reinforce course concepts through interactive tutorials and hands-on activities.
Browse courses on
Molecular Biology
Show steps
Show steps
Show steps
- Create a Coursera account
- Enroll in the 'DNA and the Mystery of Life'
- Complete each tutorial in the course
Solve online genetics problems
Show steps
Strengthen problem-solving skills and apply course concepts to real-world scenarios.
Browse courses on
Genetics
Show steps
Show steps
Show steps
- Find a reputable online genetics problem database
- Select problems at various difficulty levels
- Work through the problems, checking your answers as you go
- Review incorrect answers to identify areas for improvement
Develop a DNA replication infographic
Show steps
Enhance understanding of the complex process of DNA replication through visual representation.
Browse courses on
DNA Replication
Show steps
Show steps
Show steps
- Gather information on the steps of DNA replication
- Design a visually appealing infographic layout
- Create clear and concise graphics and text to illustrate the process
- Proofread and finalize the infographic
Contribute to open-source genetic databases
Show steps
Enhance research skills and contribute to the advancement of genetic knowledge by sharing data and collaborating with others.
Browse courses on
Genetics
Show steps
Show steps
Show steps
- Identify reputable open-source genetic databases
- Explore the databases and identify areas where you can contribute
- Contribute data, annotations, or other relevant information
- Collaborate with other contributors to ensure data quality and accuracy
Design a genetic experiment to test a hypothesis
Show steps
Apply course concepts to real-world research by designing and conducting your own genetic experiment.
Browse courses on
Genetics
Show steps
Show steps
Show steps
- Identify a research question and hypothesis
- Design the experiment, including methods and protocols
- Obtain necessary materials and resources
- Conduct the experiment and collect data
- Analyze the data and draw conclusions
Career center
Learners who complete DNA Decoded will develop knowledge and skills
that may be useful to these careers:
Molecular Biologist
Molecular Biologist
Molecular Biologists study the structure and function of molecules in living organisms, with a focus on DNA and RNA. This course, DNA Decoded, delves into the molecular structure of DNA, the process of transcription and translation, and the techniques used to manipulate DNA. For those who wish to succeed in this field, a thorough understanding of these topics is essential, making this course an invaluable resource.
Genetic Engineer
Genetic Engineer
Genetic Engineers use laboratory techniques to alter the DNA of living organisms, opening up new possibilities for medical treatments, agricultural advancements, and industrial applications. This course, DNA Decoded, provides a comprehensive overview of the structure and function of DNA, as well as the techniques used to manipulate it. With this in-depth knowledge, you will be well-prepared to pursue a career in genetic engineering and contribute to the development of innovative technologies that address real-world challenges.
Biochemist
Biochemist
Biochemists study the chemical processes that occur in living organisms. For those who wish to succeed in this field, understanding the structure and function of DNA is essential. This course, DNA Decoded, provides an in-depth exploration of DNA, including its molecular structure, how it replicates, and how it is used to create proteins. With topics that cover everything from the Human Genome Project to genetic engineering, this course could help you build a solid foundation for a career in biochemistry.
Research Scientist
Research Scientist
Research Scientists conduct scientific research to advance our understanding of the world around us. Many research scientists focus on the study of DNA and genetics. This course provides an in-depth exploration of DNA, including its molecular structure, how it replicates, and how it is used to create proteins, providing you with a strong foundation for a career in this field.
Forensic Scientist
Forensic Scientist
Forensic Scientists collect and analyze evidence to help solve crimes. One of the most important tools they use is DNA analysis. This course provides a comprehensive overview of DNA fingerprinting techniques, which can be used to identify suspects and exonerate the innocent. If you are interested in a career in forensic science, this course could give you the knowledge and skills you need to succeed.
Epidemiologist
Epidemiologist
Epidemiologists investigate the causes and patterns of disease in populations, with a focus on identifying risk factors and developing prevention strategies. This course, DNA Decoded, provides an in-depth exploration of DNA, including its molecular structure, how scientists cracked the genetic code, and what our DNA can tell us about ourselves. With a strong understanding of these topics, you will be well-equipped to contribute to the field of epidemiology by studying the genetic basis of disease and developing effective public health interventions.
Biostatistician
Biostatistician
Biostatisticians apply statistical methods to data in the biological sciences to draw meaningful conclusions. This course, DNA Decoded, explores the structure of DNA, how scientists cracked the genetic code, and what our DNA can tell us about ourselves. With this in-depth understanding of DNA and genetics, you will be well-prepared to design and conduct statistical analyses that advance our knowledge in the biological sciences.
Genetic Counselor
Genetic Counselor
Genetic Counselors help individuals and families understand and manage their genetic risks. To be successful in this field, it is essential to have a strong understanding of DNA and genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders. It also covers ethical issues related to genetic testing and counseling. If you are interested in a career as a genetic counselor, this course could provide you with the foundation you need.
Science Teacher
Science Teacher
Science Teachers educate students about the natural world, including the study of DNA and genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders, equipping you with the knowledge you need to effectively teach these concepts to your students.
Veterinarian
Veterinarian
Veterinarians diagnose and treat diseases and injuries in animals. Many animal diseases have a genetic component, so it is important for veterinarians to have a basic understanding of genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders that affect animals, providing you with the foundation you need to succeed in this field.
Wildlife Biologist
Wildlife Biologist
Wildlife Biologists study the behavior, ecology, and conservation of wild animals. Many wildlife species are threatened by habitat loss, climate change, and other environmental factors, which can have a genetic impact on their populations. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders that affect wildlife, equipping you with the knowledge you need to understand and address these threats.
Medical Doctor
Medical Doctor
Medical Doctors diagnose and treat diseases and injuries. Many medical conditions have a genetic component, so it is important for doctors to have a basic understanding of genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders. If you are interested in a career as a medical doctor, this course could provide you with the foundation you need to understand the genetic basis of disease.
Registered Nurse
Registered Nurse
Registered Nurses provide care to patients in a variety of settings. Many medical conditions have a genetic component, so it is important for registered nurses to have a basic understanding of genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders. If you are interested in a career as a registered nurse, this course could provide you with the foundation you need to understand the genetic basis of disease.
Physician Assistant
Physician Assistant
Physician Assistants provide medical care under the supervision of a physician. Many medical conditions have a genetic component, so it is important for physician assistants to have a basic understanding of genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders. If you are interested in a career as a physician assistant, this course could provide you with the foundation you need to understand the genetic basis of disease.
Pharmacist
Pharmacist
Pharmacists dispense medications and provide advice on their use. Many medications have genetic implications, so it is important for pharmacists to have a basic understanding of genetics. This course provides an overview of the basic principles of genetics, as well as information on specific genetic disorders. If you are interested in a career as a pharmacist, this course could provide you with the foundation you need to understand the genetic basis of drug action.
For more career information including salaries, visit:
OpenCourser.com/course/r8a0jc/dna
Reading list
We've selected seven books
that we think will supplement your
learning. Use these to
develop background knowledge, enrich your coursework, and gain a
deeper understanding of the topics covered in
DNA Decoded.
It smoothly integrates biological sciences with genetics to establish a strong foundation for students pursuing genetics.
An authoritative and comprehensive textbook on molecular biology, providing a deep understanding of the fundamental principles.
This well-established textbook on molecular biology provides an in-depth look at the structure and function of DNA and its role in cellular processes. It offers detailed explanations of genetic engineering techniques and their implications.
Provides crucial information for understanding the manipulation of DNA and genetic engineering, including modern research findings.
A comprehensive and up-to-date reference on genes and their role in biological processes.
Covers the principles and applications of recombinant DNA technology, providing a strong foundation in genetic engineering techniques.
A comprehensive guide to human molecular genetics, covering the latest advances in the field and their clinical implications.
For more information about how these books relate to this course, visit:
OpenCourser.com/course/r8a0jc/dna
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Rating
4.8
Effort
Approx. 22 hours
Level
Intermediate
Via
Coursera
Institution
McMaster University
Instructors
Caitlin Mullarkey
Felicia Vulcu
Language
English
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