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Jason Crumpton

In this course, I'll walk you through the four major spectroscopic methods that are covered in Organic Chemistry courses. Each method is covered in detail with background and practice problems for each method. I'll warn you about common stumbling blocks and mental hurdles students normally face, and I'll give you practical problem solving tips and tricks.  You're going to do AWESOME. :) 

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What's inside

Learning objectives

  • Generalized nmr theory via metaphor and visualization (no complex math)
  • Mass spectrometry (ms) (theory and problem solving methods)
  • How to game hydrogen (1h) nmr problems through practical problem solving methods
  • How to game carbon (13c) nmr problems through practical problem solving methods
  • Infrared (ir) spectroscopy (theory and problem solving methods)

Syllabus

IR Spectroscopy - Part I
Electromagnetic Radiation
Bonds as Springs
Anatomy of an IR Spectrum
Read more
Anatomy of an IR spectrum
Common Absorption Regions and Hooke's Law
Alkanes
Alkenes
Alkynes
Comparing Alkanes vs. Alkenes vs. Alkynes
IR Spectroscopy - Part II
Alcohols
Carboxylic acids
Comparing Alcohols vs. Carboxylic acids
Comparing Carboxylic acids vs. Esters
Comparing Esters vs. Ethers
Ketones vs. Alkenes (A surprisingly subtle choice)
Amines
Aldehydes
Mass Spectrometry - Part I
Intro to MS - Theory and Practice
Base Peak vs. Molecular Ion vs. M+1 peak
Identifying Base vs. Molecular vs. M+1 peak
Heterolytic vs. Homolytic Fragmentation
Simple Alkane Fragmentation
Mass of Common Fragments
Fragment Stability and Relative Abundance
Fragment Stability and Common Fragments
Approximating Molecular Formula
12C and 13C isotopes (M and M+1)
A Space Analogy for Isotopic Abundance
Mass Spectrometry - Part II
The Nitrogen Rule
Alkyl Halides (Bromine) - 79Br and 81Br
Alkyl Halides (Chlorine) - 35Cl and 37Cl
Alkyl Halides
Ethers
Ketones and the McLafferty Rearrangement
(Intro, # of Peaks, and Chemical Shifts)
Intro to NMR - Theory and Practice
Anatomy of a NMR Spectrum
Predicting Number of Peaks - CH2 Equivalence
Predicting Number of Peaks - CH3 Equivalence
(VIDEO QUIZ!) Predicting Number of Peaks
Predicting Number of Peaks - Alkenes
Predicting Number of Peaks - Benzene
Predicting Chemical Shifts
(VIDEO QUIZ!) Predicting Chemical Shifts
(COMBO PRACTICE!!) - Chemical Shifts + Number of Peaks
1H NMR - Part II (Integration Values and Splitting)
Integration Values
Integration Practice
(COMBO PRACTICE!!) - Chemical Shifts + Number of Peaks + Integration
Splitting Patterns
Splitting Pattern Practice
(COMBO PRACTICE!!) - ALL SKILLS!
1st Big Structure Prediction (DU introduction)
(VIDEO QUIZ!) 2nd Big Structure Prediction
Exchangeable Protons - (Alcohols, Amines, and Carboxylic acids)
Funky Splitting Patterns - (Propyl groups)
Funky Splitting Patterns - (Alkenes)
Funky Splitting Patterns - (Chiral Carbons)
13C NMR Spectroscopy
Intro to 13C NMR
Predicting Number of Peaks
Chemical Shifts
Integration Values and Splitting
(EXTRA PRACTICE!!) - Challenge Combo Problems
1H NMR + 13C NMR
1H NMR + IR
1H NMR + IR + MS (First Example)
1H NMR + IR + MS (Second Example)
1H NMR + 13C NMR + IR + MS
1H NMR + 13C NMR + IR + MS (FinalExample) :'(

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Develops skills in reading IR spectroscopy, which is standard in the pharmaceutical industry
Taught by Jason Crumpton, who is recognized for their work in organic chemistry
Develops skills in NMR spectroscopy, which is core for chemistry and biochemistry
Develops skills in mass spectrometry, which is key for chemistry and biochemistry
Covers the basics of NMR spectroscopy, which is appropriate for beginners
Covers the basics of MS, IR, and NMR, which is appropriate for beginners

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Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Organic Chemistry: Spectroscopy Master Class with these activities:
NMR Practice Problems
Reinforce your understanding of NMR spectroscopy by solving practice problems.
Show steps
  • Find practice problems online or in textbooks
  • Solve the problems independently
  • Check your answers and identify areas where you need more practice
Mass Spectrometry Practice Problems
Enhance your understanding of mass spectrometry by solving practice problems.
Browse courses on Mass Spectrometry
Show steps
  • Find practice problems online or in textbooks
  • Solve the problems independently
  • Check your answers and identify areas where you need more practice
Guided Tutorials for NMR Interpretation
Following guided tutorials will provide you with additional support and practice in interpreting NMR spectra.
Show steps
  • Find reputable sources that provide tutorials for NMR interpretation.
  • Follow the tutorials step-by-step.
  • Apply the techniques to practice problems.
Seven other activities
Expand to see all activities and additional details
Show all ten activities
Online NMR Tutorials
Expand your knowledge of NMR spectroscopy by exploring online tutorials and resources.
Show steps
  • Search for reputable online tutorials on NMR spectroscopy
  • Watch the tutorials and take notes on key concepts
  • Practice applying the concepts you learned to solve NMR problems
Spectroscopy Drills
Completing drills on MS and IR will help you gain proficiency in these techniques.
Browse courses on Mass Spectrometry
Show steps
  • Practice identifying the molecular ion peak.
  • Interpret fragmentation patterns.
  • Identify functional groups based on IR spectra.
Practice Problems for NMR
Solving practice problems will help solidify your understanding of the theory and methods covered in the course.
Show steps
  • Identify the type of NMR spectroscopy (1H or 13C) you are working with.
  • Determine the number of peaks in the spectrum.
  • Predict the chemical shifts of the protons or carbons.
  • Interpret the splitting patterns.
Create a Study Guide
Summarize key concepts and techniques from the course by creating a comprehensive study guide.
Show steps
  • Identify the main concepts and techniques covered in the course
  • Summarize each concept and technique in a concise and clear manner
  • Organize the study guide logically, using headings and subheadings
Attend a Chemistry Conference
Connect with experts and learn about the latest advancements in spectroscopy by attending a chemistry conference.
Browse courses on Chemistry
Show steps
  • Research upcoming chemistry conferences
  • Register for a conference that aligns with your interests
  • Attend presentations and workshops on spectroscopy
  • Network with other attendees and share knowledge
Volunteer at a Chemistry Lab
Gain practical experience and contribute to the field by volunteering at a chemistry lab.
Browse courses on Chemistry
Show steps
  • Identify chemistry labs in your area that offer volunteer opportunities
  • Contact the lab and inquire about volunteer positions
  • Attend training sessions and learn about the lab's procedures
  • Assist with experiments and data analysis
Tutor Organic Chemistry Students
Enhance your understanding of spectroscopy while helping others learn by tutoring organic chemistry students.
Browse courses on Organic Chemistry
Show steps
  • Identify students who need assistance with organic chemistry
  • Offer your help and schedule tutoring sessions
  • Review organic chemistry concepts and spectroscopy techniques
  • Provide guidance and support to students as they solve problems

Career center

Learners who complete Organic Chemistry: Spectroscopy Master Class will develop knowledge and skills that may be useful to these careers:
Organic Chemist
Organic Chemists study the structure, properties, and reactions of organic compounds. They work in various industries, including pharmaceuticals, chemicals, and materials science. This course is highly relevant for aspiring Organic Chemists, as it provides in-depth knowledge of spectroscopic techniques essential for characterizing and analyzing organic molecules. By mastering these techniques, Organic Chemists can excel in research and development of new drugs, materials, and other products.
Spectroscopist
Spectroscopists specialize in the use of spectroscopy to analyze the structure and properties of matter. They work in various fields, including chemistry, physics, and materials science. Organic Chemistry: Spectroscopy Master Class is a highly specialized course that provides Spectroscopists with advanced knowledge and skills in spectroscopic techniques. By mastering these techniques, Spectroscopists can excel in research and development, contributing to advancements in fields such as drug discovery and materials characterization.
Polymer Chemist
Polymer Chemists research and develop polymers, which are large molecules made up of repeating units. They work in various industries, including plastics, coatings, and adhesives. Organic Chemistry: Spectroscopy Master Class is highly relevant for Polymer Chemists, as it provides in-depth knowledge of spectroscopic techniques used to characterize and analyze polymers. By mastering these techniques, Polymer Chemists can excel in the design and development of new polymeric materials with tailored properties.
Pharmaceutical Chemist
Pharmaceutical Chemists research and develop new drugs and treatments for diseases. They collaborate with other scientists and medical professionals to bring new therapies to market. Organic Chemistry: Spectroscopy Master Class provides a solid foundation for Pharmaceutical Chemists, as it equips them with advanced spectroscopic techniques used in drug discovery and development. By understanding these techniques, Pharmaceutical Chemists can contribute to the design and optimization of new drugs with improved efficacy and safety.
Research Scientist
Research Scientists conduct scientific research to advance knowledge in various fields. They work in academia, government, and industry. Organic Chemistry: Spectroscopy Master Class provides a valuable foundation for Research Scientists, as it enhances their understanding of spectroscopic techniques used to characterize and analyze materials at the molecular level. By mastering these techniques, Research Scientists can contribute to groundbreaking discoveries in fields such as drug development, renewable energy, and environmental science.
Chemistry Teacher
Chemistry Teachers educate students about the fundamental principles and applications of chemistry. This course aligns well with the needs of Chemistry Teachers, as it delves into advanced spectroscopic techniques that are often not covered in undergraduate chemistry curricula. By mastering these techniques, Chemistry Teachers can stay up-to-date with the latest advancements in the field and effectively convey complex chemical concepts to their students.
Physical Chemist
Physical Chemists study the physical properties and behavior of matter. They work in various fields, including materials science, energy, and environmental science. Organic Chemistry: Spectroscopy Master Class provides a valuable foundation for Physical Chemists, as it enhances their understanding of spectroscopic techniques used to probe the structure and dynamics of materials at the molecular level. By mastering these techniques, Physical Chemists can contribute to advancements in fields such as solar energy conversion and battery development.
Materials Scientist
Materials Scientists research and develop new materials with improved properties. They work in various industries, including aerospace, electronics, and healthcare. Understanding spectroscopic techniques is essential for Materials Scientists, as it allows them to characterize the structure and properties of materials at the molecular level. This course provides a comprehensive overview of spectroscopic methods, enabling Materials Scientists to analyze and design materials with tailored properties.
Quality Control Chemist
Quality Control Chemists ensure that products meet quality standards and specifications. They work in various industries, including food, pharmaceuticals, and manufacturing. Organic Chemistry: Spectroscopy Master Class provides a strong foundation for Quality Control Chemists, as it equips them with advanced spectroscopic techniques used to analyze and identify impurities and contaminants in products. By mastering these techniques, Quality Control Chemists can contribute to the production of safe and high-quality products.
Medical Physicist
Medical Physicists apply physics principles to medical diagnosis and treatment. They use advanced imaging techniques, such as MRI and X-rays, to visualize and analyze the human body. Organic Chemistry: Spectroscopy Master Class provides a valuable foundation for Medical Physicists, as it enhances their understanding of spectroscopic techniques used in medical imaging. By mastering these techniques, Medical Physicists can contribute to the development and optimization of diagnostic tools, leading to improved patient care.
Chemical Engineer
Chemical Engineers design and operate chemical plants and processes. They apply principles of chemistry, physics, and mathematics to solve technical problems in industries such as manufacturing, energy, and pharmaceuticals. Understanding spectroscopic techniques is valuable for Chemical Engineers, as it enables them to analyze and optimize chemical processes, ensuring product quality and efficiency. This course provides a solid foundation in spectroscopy, equipping learners with the tools to excel in this field.
Forensic Scientist
Forensic Scientists analyze evidence to aid in criminal investigations. They use scientific methods to examine physical evidence, such as DNA, fingerprints, and trace elements. Organic Chemistry: Spectroscopy Master Class may be useful for aspiring Forensic Scientists, as it provides a strong foundation in spectroscopic techniques used to identify and characterize unknown substances commonly encountered in forensic investigations.
Toxicologist
Toxicologists study the effects of toxic substances on living organisms. They work in various fields, including environmental science, public health, and forensics. Organic Chemistry: Spectroscopy Master Class may be useful for aspiring Toxicologists, as it provides a foundation in spectroscopic techniques used to identify and characterize toxic compounds in environmental samples and biological specimens. This knowledge can support Toxicologists in assessing the risks posed by toxic substances and developing strategies to mitigate their impact.
Biochemist
Biochemists investigate the chemical processes within living organisms. This course may be useful for aspiring Biochemists, as it provides a foundation in spectroscopic techniques commonly used to study the structure and dynamics of biological molecules, such as proteins and nucleic acids. Understanding these techniques is crucial for analyzing and interpreting experimental data in biochemistry research.
Analytical Chemist
Analytical Chemists help organizations identify the composition and structure of materials. They analyze products ranging from food and drugs to fuels and plastics. As an Analytical Chemist, you'll play a key role in quality control, research and development, and forensic investigations. Organic Chemistry: Spectroscopy Master Class may be useful as this course teaches key techniques for characterizing and identifying chemical compounds through spectroscopic analysis. A background in organic chemistry is required for this role.

Reading list

We've selected nine books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Organic Chemistry: Spectroscopy Master Class.
Textbook commonly used at academic institutions and by industry professionals. It provides a comprehensive overview of organic chemistry, including spectroscopy.
Provides a more accessible introduction to spectroscopy, with a focus on the practical aspects of using spectroscopic techniques.
Provides a comprehensive overview of organic spectroscopy, with a focus on the interpretation of spectra.
Provides a more advanced look at spectroscopic methods, with a focus on the applications of spectroscopy in organic chemistry.
Provides a comprehensive overview of NMR spectroscopy, with a focus on the principles and applications of this technique.
Provides a comprehensive overview of infrared spectroscopy, with a focus on the principles and applications of this technique.
Provides a comprehensive overview of applications of absorption spectroscopy of organic compounds.

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