May 13, 2024
3 minute read
Tumor suppressor genes, often abbreviated to TSGs, are genes that code for proteins that help to prevent or suppress the development of cancer. TSGs do this by controlling cell growth, repairing damaged DNA, and inducing cell death in cells that have sustained irreparable DNA damage. Tumor suppressor genes are vital for maintaining the health and integrity of the genome and preventing the development of cancer.
How do Tumor Suppressor Genes Work?
TSGs work in several ways to prevent cancer. One of the most important functions of TSGs is to control cell growth. TSGs code for proteins that regulate the cell cycle, ensuring that cells only divide when necessary. If TSGs are mutated or deleted, cells may divide uncontrollably, leading to the development of tumors.
In addition to controlling cell growth, TSGs also play a role in repairing damaged DNA. TSGs code for proteins that repair damaged DNA or induce cell death in cells with irreparable DNA damage. If TSGs are mutated or deleted, damaged DNA may not be repaired properly, leading to the accumulation of mutations and the development of cancer.
What Happens When Tumor Suppressor Genes Are Mutated or Deleted?
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Reading list
We've selected five books
that we think will supplement your
learning. Use these to
develop background knowledge, enrich your coursework, and gain a
deeper understanding of the topics covered in
Tumor Suppressor Genes.
Provides a comprehensive overview of the biology of cancer, including the role of tumor suppressor genes in cancer development. Written by a leading expert in the field, this book is an essential resource for students and researchers alike.
Focuses specifically on the role of tumor suppressor genes in cancer development. It covers the latest research on the identification, function, and regulation of tumor suppressor genes. This book is an excellent resource for researchers and clinicians working in the field of cancer biology.
Provides a broad overview of the genetics of cancer, including the role of tumor suppressor genes. It is written in a clear and concise style, making it accessible to a wide range of readers.
Provides a comprehensive overview of the molecular biology of cancer, including the role of tumor suppressor genes. It is written in a clear and concise style, making it accessible to a wide range of readers.
Focuses on the cytogenetic changes that occur in cancer cells. It includes a chapter on the role of tumor suppressor genes in cancer development.
For more information about how these books relate to this course, visit:
OpenCourser.com/topic/ptxmms/tumor
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