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Ralph Lydic, Ph.D. and Helen Baghdoyan, Ph.D.

The objective of this course is to give students the most up-to-date information on the biological, personal, and societal relevance of sleep. Personal relevance is emphasized by the fact that the single best predictor of daytime performance is the quality of the previous night's sleep. The brain actively generates sleep, and the first section of the course is an overview of the neurobiological basis of sleep control. The course provides cellular-level understanding of how sleep deprivation, jet lag, and substances such as alcohol, ,caffeine, and nicotine alter sleep and wakefulness. The second section of the course covers sleep-dependent changes in physiology and sleep disorders medicine. Particular emphasis will be placed on disorders of excessive sleepiness, insomnia, and sleep-dependent changes in autonomic control. Chronic sleep deprivation impairs immune function and may promote obesity. Deaths due to all causes are most frequent between 4:00 and 6:00 a.m., and this second section of the class highlights the relevance of sleep for preventive medicine. The societal relevance of sleep will be considered in the final section of the class. In an increasingly complex and technologically oriented society, operator-error by one individual can have a disastrous negative impact on public health and safety. Fatigue-related performance decrements are known to have contributed as causal factors to nuclear power plant failures, transportation disasters, and medical errors.

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What's inside

Syllabus

Unit 01 - Neurobiology Section: Course Introduction & Neurobiology of Sleep and Wakefulness (Part One) - (Standard Track & Honors Track)
This unit begins with a Course Overview video from Ralph Lydic, Ph.D., followed by the first portion of the Neurobiology of Sleep and Wakefulness lecture, delivered by Helen Baghdoyan, Ph.D. PLEASE NOTE: Only the Course Overview video, and the Getting Started and Syllabus readings are required for students who have chosen to engage in the Standard Track portion of the course content. Standard track students may also bypass all content in units 2, 3, and 4, and instead move directly to unit 5 after viewing the Course Overview video.
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Unit 02 - Neurobiology Section: Neurobiology of Sleep and Wakefulness (Part Two) - (Honors Track)
Unit 2 continues the lecture from Helen Baghdoyan, Ph.D. on the Neurobiology of Sleep and Wakefulness. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification.
Unit 03 - Neurobiology: Mathematical Modeling of Sleep-Wake Regulation - (Honors Track)
Unit 3 continues the Neurobiology section of the content with a lecture from Victoria Booth, Ph.D. on the Mathematical Modeling of Sleep-Wake Regulation. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification.
Unit 04 - Neurobiology: Molecular Biology and Genetics of Sleep - (Honors Track)
Unit 4 closes out the Neurobiology section with a lecture from Chiara Cirelli, Ph.D. on Molecular Biology and the Genetics of Sleep. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification.
Unit 05 - Medicine: Overview of Sleep Medicine - Ronald Chervin, M.D. - (Standard Track)
Unit 5 marks the beginning of the Medicine section of the course. This unit features an overview of Sleep Medicine from Ronald Chervin, M.D.
Unit 06 - Medicine: Disordered Sleep and Breathing Alters Cardiovascular Health - (Standard Track)
Unit 6 continues the Medicine section of the course, featuring a lecture from Helena Schotland, M.D. exploring how Disordered Sleep and Breathing may alter Cardiovascular Health.
Unit 07 - Medicine: Sleep and Psychiatric Disorders - (Standard Track)
Unit 7 further continues the Medicine section of the course with a lecture on the relationship of Sleep and Psychiatric Disorders from Eric Nofzinger, M.D
Unit 08 - Medicine: Insomnia: Causes and Consequences - (Standard Track)
Unit 8 further continues the Medicine section of the course with a lecture from Christopher Drake, Ph.D. on the causes and consequences of Insomnia.
Unit 09 - Medicine: Treatments for Insomnia - (Standard Track)
Unit 9 further continues the Medicine section of the course with a lecture from J. Todd Arendt, Ph.D. on the range of available treatments for Insomnia.
Unit 10 - Medicine: Sleep and Anesthesia - (Standard Track)
Unit 10 brings the Medicine section of the course to a close with a lecture on Sleep and Anesthesia delivered by George Mashour, M.D.
Unit 11 - Society: Circadian Rhythms, Sleep, and Health - (Standard Track)
Unit 11 kicks off the Society section of the course with a lecture on Circadian Rhythms, Sleep, and Health from Theresa Lee, Ph.D.
Unit 12 - Society: Daytime Sleepiness and Sleep Need - Thomas Roth, Ph.D. (Standard Track)
Unit 12 wraps up the final section of the course and the Society section of the content with a lecture on Daytime Sleepiness and Sleep Need by Thomas Roth, Ph.D.

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Examines the most up-to-date information on the biological, personal, and societal impact of sleep
Taught by Ralph Lydic, Ph.D. and Helen Baghdoyan, Ph.D., renowned experts in sleep science
Develops a cellular-level understanding of sleep-related physiology and disorders
Emphasizes the importance of sleep for personal and societal health and safety
Delivers content through a multi-modal format, including videos, readings, and discussions

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Reviews summary

Highly praised sleep science course

Learners say this course on Sleep: Neurobiology, Medicine, and Society is largely positive, engaging, and offers a comprehensive view of sleep research. Well-received lectures cover sleep's neurobiological, medical, and societal aspects. The course is highly recommended for learners of all levels who want to advance their knowledge of sleep.
Course is very detailed and covers wide range of topics related to sleep.
"This course is a complete and wide vision about a very important theme."
"This is a comprehensive course that covers many aspects of sleep in great detail."
"The course is very good, teachers are so prepared and understandable, the arguments are a lot of specific and put me curiosity."
Expert instructors present material clearly and professionally.
"Excellent course - Comprehensive knowledge from experts in a highly digestible format."
"really good - fantastically knowledgeable teachers, evidence based and interesting."
"Outstanding balance of neurobiology and relevant clinical content!!! Way better than my medical school!"
Many learners highly recommend this course to others interested in sleep.
"Amazing course! Loved it."
"This course is one of the best on the Coursera platform."
"I'm a PhD candidate in Neuroscience and I work on the circadian rhythm dysfunctions in Parkinson's Disease. The lectures were very interesting and useful for me and I have learned a lot so far,"
Course requires a significant time commitment, especially for those in Standard Track.
"Unable to take the units I am interested in on the standard track."
"This course is way too technical for people in the Standard Track."
"Was very informative sessions."
Some learners find course material overly technical, especially in neurobiology section.
"The neurobiology section is the only part that is worth the effort, but more importantly than everything else, time."
"Content is too lengthy i.e too many topics and lengthy explanation."
"It’s a bit out of date. Please add some update information."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Sleep: Neurobiology, Medicine, and Society with these activities:
Refine scientific writing skills
Enhance ability to write clear and concise scientific reports
Show steps
  • Review style guide and grammar rules
  • Revise a scientific paper or report
Compile sleep study resources
Gather and organize relevant research materials for future reference
Show steps
  • Search databases for sleep-related studies
  • Review abstracts and select relevant articles
  • Organize articles by topic or research question
Engage in peer discussion
Exchange ideas and learn from diverse perspectives
Browse courses on Sleep Disorders
Show steps
  • Form a study group with classmates
  • Discuss assigned readings and case studies
  • Present research findings to the group
Three other activities
Expand to see all activities and additional details
Show all six activities
Practice insomnia treatment techniques
Develop practical skills in managing sleep disturbances
Show steps
  • Read about different insomnia treatments
  • Practice relaxation exercises before bed
Mentor students or individuals with sleep-related concerns
Reinforce knowledge and develop empathy by guiding others
Browse courses on Sleep Disorders
Show steps
  • Volunteer at a sleep clinic or support group
  • Provide guidance on sleep hygiene and disorder management
Contribute to sleep research
Gain hands-on experience in data collection and analysis
Show steps
  • Identify a research project or contribute to existing studies
  • Collect data using surveys or sleep monitoring devices
  • Analyze and interpret data to contribute to scientific literature

Career center

Learners who complete Sleep: Neurobiology, Medicine, and Society will develop knowledge and skills that may be useful to these careers:
Sleep Technologist
A Sleep Technologist plays a critical role in the diagnosis and treatment of sleep disorders. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the medical and societal implications of sleep disorders. This knowledge will be essential for your success as a Sleep Technologist, as you will need to be able to understand and interpret the results of sleep studies and develop treatment plans for patients with sleep disorders.
Neurologist
Neurologists are medical doctors who specialize in the diagnosis and treatment of disorders of the nervous system, including the brain and spinal cord. This course can help you build a foundation in the neurobiology of sleep and wakefulness, which will be essential for your success as a Neurologist. You will need to be able to understand the complex interactions between the brain and the body, and how these interactions can affect sleep and wakefulness.
Psychiatrist
Psychiatrists are medical doctors who specialize in the diagnosis and treatment of mental disorders. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the relationship between sleep and psychiatric disorders. This knowledge will be essential for your success as a Psychiatrist, as you will need to be able to understand how sleep disorders can affect mental health, and how mental health disorders can affect sleep.
Pediatrician
Pediatricians are medical doctors who specialize in the care of infants, children, and adolescents. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the unique sleep needs of children. This knowledge will be essential for your success as a Pediatrician, as you will need to be able to diagnose and treat sleep disorders in children, and to provide guidance to parents on how to promote healthy sleep habits in their children.
Occupational Therapist
Occupational Therapists help people with disabilities or injuries to regain or improve their ability to perform everyday activities. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the impact of sleep disorders on daily functioning. This knowledge will be essential for your success as an Occupational Therapist, as you will need to be able to assess the impact of sleep disorders on your clients, and to develop treatment plans to help them improve their sleep and overall function.
Pharmacist
Pharmacists are responsible for dispensing medications and providing information about their use. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the effects of medications on sleep. This knowledge will be essential for your success as a Pharmacist, as you will need to be able to advise patients on the potential effects of medications on their sleep, and to recommend non-pharmacological treatments for sleep disorders.
Registered Nurse
Registered Nurses provide care to patients in a variety of settings, including hospitals, clinics, and long-term care facilities. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the assessment and management of sleep disorders. This knowledge will be essential for your success as a Registered Nurse, as you will need to be able to assess and manage sleep disorders in your patients, and to provide education and support to patients and their families.
Social Worker
Social Workers help people to cope with difficult life situations, such as poverty, mental illness, and addiction. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the impact of sleep disorders on mental health and well-being. This knowledge will be essential for your success as a Social Worker, as you will need to be able to assess the impact of sleep disorders on your clients, and to develop treatment plans to help them improve their sleep and overall well-being.
Health Educator
Health Educators develop and implement programs to promote healthy behaviors and prevent disease. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the importance of sleep for overall health and well-being. This knowledge will be essential for your success as a Health Educator, as you will need to be able to educate people about the importance of sleep, and to develop and implement programs to promote healthy sleep habits.
Journalist
Journalists write and report on news and current events. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the societal implications of sleep disorders. This knowledge will be essential for your success as a Journalist, as you will need to be able to write and report on the latest developments in sleep research, and to educate the public about the importance of sleep.
Policy Analyst
Policy Analysts research and analyze public policy issues, and make recommendations for policy changes. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the societal implications of sleep disorders. This knowledge will be essential for your success as a Policy Analyst, as you will need to be able to understand the impact of sleep disorders on public health and safety, and to develop policy recommendations to address these issues.
Teacher
Teachers educate students in a variety of subjects, including science, math, and social studies. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the importance of sleep for learning and memory. This knowledge will be essential for your success as a Teacher, as you will need to be able to understand the impact of sleep on your students' learning, and to create a classroom environment that promotes healthy sleep habits.
Ergonomist
Ergonomists design workspaces and products to be safe and comfortable for users. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the impact of work environment on sleep. This knowledge will be essential for your success as an Ergonomist, as you will need to be able to understand the impact of work environment on sleep, and to design workspaces that promote healthy sleep habits.
Lighting Designer
Lighting Designers design lighting systems for a variety of spaces, including homes, offices, and public buildings. This course can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the impact of light on sleep. This knowledge will be essential for your success as a Lighting Designer, as you will need to be able to understand the impact of light on sleep, and to design lighting systems that promote healthy sleep habits.
Architect
Architects design buildings and other structures. This course may be useful for you as an Architect, as it can help you build a foundation in the neurobiology of sleep and wakefulness, as well as the impact of building design on sleep. This knowledge can be useful for designing buildings that promote healthy sleep habits.

Reading list

We've selected eight books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Sleep: Neurobiology, Medicine, and Society.
Is an extensive reference on sleep medicine, covering the neurobiology and physiology of sleep, sleep disorders, and the treatment of sleep problems. It valuable resource for students and practitioners in the field of sleep medicine. It covers a wide range of topics relevant to the course, including the neurobiology of sleep and wakefulness, sleep disorders medicine, and the societal relevance of sleep.
This handbook provides a comprehensive overview of sleep and sleep disorders. It valuable resource for students and practitioners in the field of sleep medicine.
This handbook provides a comprehensive overview of sleep research and clinical practice. It covers a wide range of topics relevant to the course, including the neurobiology of sleep and wakefulness, sleep disorders medicine, and the societal relevance of sleep.
Provides an overview of behavioral sleep medicine, including the assessment and treatment of sleep disorders. It valuable resource for students and practitioners in the field of sleep medicine.
Provides an overview of the relationship between sleep and health. It valuable resource for students and practitioners in the field of public health.
Provides an overview of the relationship between sleep and society. It valuable resource for students and practitioners in the field of public health.
Provides an overview of the relationship between sleep and aging. It valuable resource for students and practitioners in the field of geriatrics.
Provides an overview of the relationship between sleep and performance. It valuable resource for students and practitioners in the field of sports psychology.

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