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Patrick J O'Malley, D.Sc

The course introduces the three key spectroscopic methods used by chemists and biochemists to analyse the molecular and electronic structure of atoms and molecules. These are UV/Visible , Infra-red (IR) and Nuclear Magnetic Resonance (NMR) spectroscopies. The content is presented using short focussed and interactive screencast presentations accompanied by formative quizzes to probe understanding of the key concepts presented. Numerous exercises are provided to facilitate mastery of each topic. A unique virtual spectroscopic laboratory is made available to enable students to measure and analyse spectra online. Assessment is via summative quizzes completed during the course period.

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What's inside

Syllabus

Ultraviolet and Visible Spectroscopy
In this first week we introduce the electromagnetic spectrum and the origin of transitions giving rise to ultraviolet and visible (UV/Vis) spectra. You will learn that electronic transitions are caused by absorption of radiation in the UV/Vis region of the electromagnetic spectrum. The reason for the wavelength and intensity of bands will be described and the colour origin of certain compounds will be discussed. You will also be shown how UV/Vis spectroscopy is performed and you will be able to run and analyse your own spectra. As the final activity in this module you are given a link to view how to obtain a UV/Visible spectrum in the laboratory. Good luck, try and participate in the discussion forums to enhance your learning and don't forget to complete the end of week laboratory quiz which contributes to your final mark.
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Infrared Spectroscopy
In this module we introduce the theory underpinning infrared (IR) spectroscopy and show examples of analysis using the technique. Transitions between the vibrational energy levels of molecules occurs in the infrared region of the electromagnetic spectrum. We start with the theory underlying vibration using the simple harmonic oscillator model. Analysis of more complex molecules is introduced using group frequencies and number of vibrational modes. You will also be shown how to obtain an infrared spectrum and will have an opportunity to run your own spectrum. At the end of this module you are given a link to view how to obtain an infra red spectrum in the laboratory. Don't forget to complete the end of week laboratory quiz which contributes to your final mark for this course.
Nuclear Magnetic Resonance (NMR) Spectroscopy
This week we concentrate on Nuclear Magnetic Resonance (NMR) spectroscopy. Here a magnetic field is used to create energy levels for magnetic nuclei present in a molecule. Transition between these energy levels occurs in the radiofrequency region of the electromagnetic spectrum. The positions of the bands in the observed spectrum is dependent on the shielding of the nuclei by the local electronic structure, giving rise to a parameter known as chemical shift. Bands also display fine structure caused by spin-spin coupling with neighbouring nuclei. Examples on the analysis of NMR spectra for structure determination will be given. As the final activity in this module you are given a link to view how to obtain an NMR spectrum in the laboratory. Don't forget to compete this end of week laboratory quiz which contributes to your final mark.
Final Assessment

Good to know

Know what's good
, what to watch for
, and possible dealbreakers
Teaches students the fundamental concepts of spectroscopy and teaches them how to use their knowledge of spectroscopy to analyze the molecular and electronic structure of atoms and molecules
Utilizes concise video lectures and quizzes to ensure learners' comprehension of the materials
Provides virtual spectroscopic laboratory to enable learners to measure and analyze spectra online

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Reviews summary

Fundamentals of molecular spectroscopy

Learners say this course is a good introduction to the fundamental principles of molecular spectroscopy. It covers the basics of UV, IR, and NMR spectroscopy. The course is well-received by learners and features engaging assignments, such as lab quizzes. The instructor, Patrick O'Malley, is knowledgeable and explains concepts clearly. The course is a great resource for students, researchers, and anyone interested in spectroscopy.
The course includes a variety of helpful resources, such as lecture notes, problem sets, and practice quizzes. These resources help learners to review the material and test their understanding of the concepts.
"notes were really informative and helpful."
"Assignment questions were of a good level."
"The workshop questions were interesting to do using the spectra."
This course is well-structured, with a logical progression of topics. The course covers the fundamentals of molecular spectroscopy in a clear and concise way.
"This course is very useful in learning all the spectroscopic techniques."
"The course was very informative with lot of emphasis given on SI units and its conversion to other metric forms."
"The subject is more useful to my further studies."
The lectures are informative and engaging. The instructor, Dr. O'Malley, is a knowledgeable and experienced teacher who presents the material in a clear and engaging way.
"This course gives a great overview of UV, Visible, Infrared and NMR spectroscopy."
"I learned a lot about the physics behind spectroscopy."
"The explanations are very easy to understand."
The course features a variety of engaging assignments, including lab quizzes and problem sets. These assignments help learners to apply the concepts they learn in the lectures.
"Great course for those who are actually interested in this field well really easy to understand and useful."
"It was really a wonderful course and I got to learn more about the spectroscopy and I thank Coursera for offering this course"
"I found the course very helpful and forms the basis of in depth study."
The course is somewhat limited in depth. It provides a good overview of the fundamentals of molecular spectroscopy, but it does not go into great detail on any one topic.
"It was useful only for already subject known candidates."
"Course is quite outdated and new modified course on this very important topic must be launched with better teaching methods."
"The lectures could have been more clear and planned."
Some learners have reported experiencing technical issues with the course, such as problems with the quizzes or difficulty viewing the videos.
"In initial videos, the coughing was disturbing."
"Very interesting lectures, topics explained pretty clear. But Eng subs are not very good and some practice quizzes have incomplete text."
"Errors in the quices that need to be improved to make it a 5-star course."

Activities

Be better prepared before your course. Deepen your understanding during and after it. Supplement your coursework and achieve mastery of the topics covered in Introduction to Molecular Spectroscopy with these activities:
Review Basic Chemistry Concepts
Reviewing basic chemistry principles will provide a solid foundation for understanding spectroscopic techniques.
Browse courses on Atomic Structure
Show steps
  • Identify areas of weakness in your chemistry knowledge.
  • Find resources such as textbooks, online courses, or tutorials to refresh your understanding.
Review Fundamental Chemistry Concepts
Refresh your foundational chemistry knowledge to support your learning in spectroscopy.
Show steps
  • Review notes or textbooks on basic chemistry concepts.
  • Complete practice problems on atomic structure, molecular bonding, and chemical reactions.
Summarize Infrared Spectroscopy Concepts
Summarizing key infrared spectroscopy concepts will solidify your understanding and improve recall.
Browse courses on Infrared Spectroscopy
Show steps
  • Review infrared spectroscopy principles and applications.
  • Create a summary in your own words, highlighting the most important concepts.
  • Regularly review your summary to reinforce your knowledge.
Nine other activities
Expand to see all activities and additional details
Show all 12 activities
Solve UV/Vis Spectroscopy Problems
Regular practice with UV/Vis spectroscopy problems will enhance your problem-solving skills and reinforce fundamental concepts.
Show steps
  • Identify and gather practice problems and exercises.
  • Attempt to solve the problems on your own.
  • Check your solutions against provided answer keys or consult online resources.
  • Analyze incorrect solutions to identify knowledge gaps.
Practice Spectrophotometry Experiments
Following online tutorials on spectroscopy simulations will provide you hands-on experience in performing experiments and interpreting results.
Browse courses on Spectroscopy
Show steps
  • Find reputable online spectroscopy simulators.
  • Select a tutorial that aligns with your learning objectives.
  • Follow the tutorial instructions to perform virtual experiments.
  • Analyze the data and interpret the results.
  • Compare your findings with expected values and draw conclusions.
Interactive Infrared Spectroscopy Tutorial
Enhance your understanding of infrared spectroscopy through guided tutorials.
Browse courses on Infrared Spectroscopy
Show steps
  • Enroll in an online tutorial platform.
  • Complete interactive modules on IR theory and applications.
  • Practice identifying functional groups using IR spectra.
Virtual Spectroscopic Laboratory Tutorial
Practice your spectroscopic skills in a virtual environment.
Browse courses on Data Analysis
Show steps
  • Access the virtual spectroscopic laboratory.
  • Follow guided instructions to perform spectroscopic experiments.
  • Analyze and interpret the resulting spectra.
Discuss Spectroscopic Techniques
Engaging in discussions with peers will foster collaboration, exchange of ideas, and deepen your understanding of spectroscopy.
Show steps
  • Form or join a study group with fellow students.
  • Choose specific spectroscopic topics for discussion.
  • Prepare for discussions by reviewing the material and formulating questions.
  • Actively participate in the discussions, sharing your insights and listening to others' perspectives.
IR Spectral Interpretation Practice
Strengthen your ability to interpret IR spectra through repetitive exercises.
Browse courses on Infrared Spectroscopy
Show steps
  • Gather a set of IR spectra with known functional groups.
  • Identify and label the characteristic absorption bands.
  • Determine the corresponding functional groups.
NMR Spectroscopy Drill
Reinforce your understanding of NMR spectroscopy through repetitive exercises.
Show steps
  • Set up your NMR simulation software.
  • Practice identifying different nuclei and their corresponding peaks.
  • Determine the chemical shifts of protons and carbons.
  • Analyze the spin-spin coupling patterns.
Contribute to Spectroscopic Database
Apply your knowledge and contribute to a publicly available spectroscopic database.
Show steps
  • Identify an open-source spectroscopy database.
  • Download and explore the database.
  • Analyze spectra to identify missing or incomplete data.
  • Submit corrections and additions to the database.
Spectroscopic Summary Report
Consolidate your learning by creating a comprehensive summary of spectroscopic techniques.
Show steps
  • Review the principles of UV/Visible, IR, and NMR spectroscopy.
  • Identify key applications and limitations of each technique.
  • Write a report that compares and contrasts the spectroscopic methods.

Career center

Learners who complete Introduction to Molecular Spectroscopy will develop knowledge and skills that may be useful to these careers:
Chemistry Teacher
Chemistry teachers develop and deliver lesson plans for chemistry courses at the high school or college level. By enrolling in this course, chemistry teachers can explore spectroscopy in more depth, which can help them provide more engaging and effective instruction to their students. Knowledge of spectroscopic techniques is also valuable when designing and conducting laboratory experiments.
Biochemist
Biochemists study the chemical processes that occur in living organisms. This course can provide a strong foundation for a career as a biochemist, as it introduces the fundamental principles of spectroscopy. Spectroscopic techniques are widely used in biochemistry to analyze the structure and function of biological molecules.
Analytical Chemist
Analytical chemists use chemical techniques to analyze the composition and structure of materials. This course may be useful for analytical chemists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the molecular structure of materials, and this course can help analytical chemists to understand how to use spectroscopic techniques to solve problems in their field.
Materials Scientist
Materials scientists develop and study new materials for use in a variety of applications. This course may be useful for materials scientists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for characterizing the structure and properties of materials, and this course can help materials scientists to understand how to use spectroscopic techniques to solve problems in their field.
Pharmaceutical Chemist
Pharmaceutical chemists develop and test new drugs and medications. This course may be useful for pharmaceutical chemists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the structure and properties of drugs and medications, and this course can help pharmaceutical chemists to understand how to use spectroscopic techniques to solve problems in their field.
Forensic Scientist
Forensic scientists use scientific techniques to analyze evidence in criminal cases. This course may be useful for forensic scientists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of materials, and this course can help forensic scientists to understand how to use spectroscopic techniques to solve problems in their field.
Environmental Scientist
Environmental scientists study the environment and its components. This course may be useful for environmental scientists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of environmental samples, and this course can help environmental scientists to understand how to use spectroscopic techniques to solve problems in their field.
Geochemist
Geochemists study the chemistry of the Earth. This course may be useful for geochemists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of geological samples, and this course can help geochemists to understand how to use spectroscopic techniques to solve problems in their field.
Nuclear Medicine Physician
Nuclear medicine physicians use radioactive substances to diagnose and treat diseases. This course may be useful for nuclear medicine physicians who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of radioactive materials, and this course can help nuclear medicine physicians to understand how to use spectroscopic techniques to solve problems in their field.
Radiologist
Radiologists use imaging techniques to diagnose and treat diseases. This course may be useful for radiologists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of biological tissues, and this course can help radiologists to understand how to use spectroscopic techniques to solve problems in their field.
Medical Physicist
Medical physicists use physics principles to develop and use medical equipment. This course may be useful for medical physicists who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of biological tissues, and this course can help medical physicists to understand how to use spectroscopic techniques to solve problems in their field.
Biomedical Engineer
Biomedical engineers design and develop medical equipment and devices. This course may be useful for biomedical engineers who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of biological tissues, and this course can help biomedical engineers to understand how to use spectroscopic techniques to solve problems in their field.
Chemical Engineer
Chemical engineers design and operate chemical plants and processes. This course may be useful for chemical engineers who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of chemical compounds, and this course can help chemical engineers to understand how to use spectroscopic techniques to solve problems in their field.
Materials Engineer
Materials engineers develop and test new materials for use in a variety of applications. This course may be useful for materials engineers who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for characterizing the structure and properties of materials, and this course can help materials engineers to understand how to use spectroscopic techniques to solve problems in their field.
Mechanical Engineer
Mechanical engineers design and develop mechanical systems and devices. This course may be useful for mechanical engineers who want to learn more about spectroscopic techniques. Spectroscopy is a powerful tool for analyzing the composition of materials, and this course can help mechanical engineers to understand how to use spectroscopic techniques to solve problems in their field.

Reading list

We've selected 16 books that we think will supplement your learning. Use these to develop background knowledge, enrich your coursework, and gain a deeper understanding of the topics covered in Introduction to Molecular Spectroscopy.
Provides a comprehensive overview of molecular spectroscopy, covering topics such as rotational, vibrational, and electronic spectroscopy. It good reference for students and researchers in the field.
Provides a comprehensive overview of infrared spectroscopy, covering topics such as the theory of infrared spectroscopy, instrumentation, and applications. It good resource for students and researchers in the field.
This textbook provides a comprehensive treatment of vibrational spectroscopy, including the underlying theory and applications. It is written in a clear and concise style, with a focus on the molecular approach.
This textbook provides a comprehensive treatment of NMR spectroscopy, including the underlying theory and applications. It is written in a clear and concise style, with a focus on the molecular approach.
Provides a comprehensive treatment of EPR spectroscopy, including the underlying theory and applications. It is written in a clear and concise style, with a focus on the practical aspects of EPR spectroscopy.
Good introduction to the spectroscopy of atoms and molecules, covering the fundamentals of both atomic and molecular spectra. It is particularly useful for a more in-depth understanding of atomic and molecular spectroscopy.
Provides a comprehensive overview of molecular spectroscopy, covering topics such as rotational, vibrational, and electronic spectroscopy. It good resource for students and researchers in the field.
A practical guide to the application of spectroscopic methods in organic chemistry. Covers UV/Vis, IR, NMR, and MS.
This textbook provides an up-to-date and comprehensive treatment of the subject, covering topics ranging from basic principles to advanced applications. It is written in a clear and concise style, with a focus on the practical aspects of spectroscopy.
This textbook provides a comprehensive treatment of molecular spectroscopy, including the underlying quantum chemistry. It is written in a clear and concise style, with a focus on the molecular approach.
A comprehensive overview of spectroscopic methods in organic chemistry, with a focus on IR, NMR, and MS.
A classic textbook on spectroscopy, covering a wide range of spectroscopic methods.
This textbook provides a solid foundation in the fundamentals of physical chemistry, including spectroscopy. It is written in a clear and concise style, with a focus on the molecular approach.
Covers the basics of laser spectroscopy, including topics such as laser sources, optics, and detectors. It good resource for students and researchers in the field.
A popular textbook on spectroscopy, covering a wide range of spectroscopic methods.

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